+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

The cost of juvenile-onset recurrent respiratory papillomatosis



The cost of juvenile-onset recurrent respiratory papillomatosis



Archives of Otolaryngology--Head and Neck Surgery 126(8): 935-939



To assess the medical costs and the number of quality-adjusted life years lost owing to juvenile-onset recurrent respiratory papillomatosis (JORRP). We examined hospital and physician charges for JORRP surgical procedures in Maryland in 1994 adjusting for inflation and the cost-charge ratio. Centers for Disease Control and Prevention data on treatment intensity for JORRP were augmented with a review of treatment records for 18 patients with JORRP. Sensitivity analyses were performed. To illustrate the application of our cost estimates, we compare the costs of JORRP to the costs of the surgical procedures that would be necessary to prevent it. We find that the present value at birth of the cost of a single case of JORRP is $201,724 (range, $61,822-$474,334). The annual cost for a single case of JORRP is $57,996 (range, $32,407-$94,114). The annual cost of JORRP in the United States is between $40 million and $123 million depending on the prevalence. Cesarean section (CS) for women with condyloma has been suggested as a potential strategy to prevent JORRP, but its efficacy remains to be determined. Our results suggest that if only 1% of the CSs actually prevented JORRP, this strategy would be a cost-effective means to prevent JORRP. Studies to reduce the uncertainty surrounding the efficacy of CS and the effect of both CS and JORRP on families need to precede consideration of a policy of CS for women with clinically evident genital condyloma. Patients should be kept thoroughly informed about the role of CS for the prevention of JORRP and the nature of the remaining uncertainties.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 047601762

Download citation: RISBibTeXText

PMID: 10922223

DOI: 10.1001/archotol.126.8.935


Related references

Two cases of juvenile-onset and adult-onset recurrent respiratory papillomatosis. Nihon Kokyuki Gakkai Zasshi 49(9): 667-673, 2011

A comparison of risk factors in juvenile-onset and adult-onset recurrent respiratory papillomatosis. Laryngoscope 102(1): 9, 1992

Juvenile-Onset Recurrent Respiratory Papillomatosis. Pediatric Asthma Allergy & Immunology 15(1): 59-62, 2001

Juvenile-onset recurrent respiratory papillomatosis. Advances in Oto-Rhino-Laryngology 73: 105-108, 2012

Recurrent Respiratory Papillomatosis (RRP)-Juvenile Onset. Clinical Medicine. Oncology 2: 481-486, 2008

Risk factors of juvenile onset recurrent respiratory papillomatosis in the lower respiratory tract. Chinese Medical Journal 125(19): 3496-3499, 2012

National registry for juvenile-onset recurrent respiratory papillomatosis. Archives of Otolaryngology--Head and Neck Surgery 129(9): 976-982, 2003

Pathogenesis and treatment of juvenile onset recurrent respiratory papillomatosis. Otolaryngologic Clinics of North America 33(1): 187-207, 2000

Prevalence of dysplasia in juvenile-onset recurrent respiratory papillomatosis. ArchivesofOtolaryngology--HeadandNeckSurgery136(1):7, 2010

Predictors of remission in juvenile-onset recurrent respiratory papillomatosis. Archives of Otolaryngology--Head and Neck Surgery 129(12): 1275-1278, 2003

Operative management of juvenile-onset recurrent respiratory papillomatosis. Operative Techniques in Otolaryngology-Head and Neck Surgery 23(2), 2012

Risk factors for juvenile onset recurrent respiratory papillomatosis. Pediatric Infectious Disease Journal 17(5): 372-376, 1998

Clinical study of juvenile-onset recurrent respiratory papillomatosis. Zhonghua Er Bi Yan Hou Ke Za Zhi 36(6): 458-462, 2001

Survivin expression in juvenile-onset recurrent respiratory papillomatosis. Annals of Otology Rhinology and Laryngology 111(11): 957-961, 2002

Can zinc be an adjuvant therapy for juvenile onset recurrent respiratory papillomatosis?. International Journal of Pediatric Otorhinolaryngology 71(8): 1163-1173, 2007