+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

The use of the fluorescein disappearance test in the management of childhood epiphora



The use of the fluorescein disappearance test in the management of childhood epiphora



Orbit 20(3): 181-187



PURPOSE. The fluorescein disappearance test (FDT) is reported to be an objective measure of lacrimal outflow in congenital non-canalisation of the nasolacrimal system. We introduced FDT into our evaluation of children with epiphora to investigate its sensitivity/specificity with regard to symptoms in a prospective study. We also examined the FDT against findings at syringing and probing (S&P) and persistence or resolution of symptoms on follow-up. METHODS. Over a period of 16 months, 88 consecutive children (median age 12 months; range 2.5-192) with epiphora were reviewed and FDT measured at 5 and 10 minutes; 66 FDT were evaluated for inter-observer variation in a masked fashion. S&P were scheduled on the basis of symptoms, abnormal FDT and age "1 year. Normal FDT prompted review. Younger children were observed for natural history and possible resolution with repeat FDT. Equivocal symptoms and normal FDT initiated discharge and telephone review. RESULTS. Inter-observer correlation coefficient = 0.86. Sensitivity/specificity of FDT was 76/76% at 5 minutes and 63/89% at 10 minutes, respectively. In patients under 1 year of age undergoing follow-up (29 patients; 38 eyes) FDT at 10 minutes correctly predicted persistence of symptoms in 65% and resolution in 66% of eyes (follow-up 3-14 months; mean 6); 23 patients (mean age 27 months; range 12-72) underwent S&P with positive surgical findings in 20 (87%). On review, symptoms had improved in 64% eyes (20/31). CONCLUSION. FDT at 5 minutes is an objective measure of symptoms with high inter-observer agreement and agreement with surgical findings. FDT read at 10 minutes may be useful to indicate the persistence or resolution of symptoms and guide patient management.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 047758097

Download citation: RISBibTeXText

PMID: 12045910


Related references

The use of the fluorescein dye disappearance test in the management of childhood epiphora. IOVS 42(4): S31, 2001

The use of the fluorescein disappearance test in the management of childhood epiphora. Orbit 20(3): 181-187, 2001

Fluorescein dye disappearance test in patients with different degrees of epiphora. European Journal of Ophthalmology 12(5): 359-365, 2002

Fluorescein Dye Disappearance Test: A Reliable Test in Assessment of Success After Dacryocystorhinostomy Procedure. Ophthalmic Plastic and Reconstructive Surgery 31(4): 296-299, 2016

The fluorescein disappearance test (FDT): an evaluation of its use in infants. Journal of Pediatric Ophthalmology and Strabismus 28(6): 302-305, 1991

Voluntary blinking and use of 0.25% dye on fluorescein dye disappearance test. Canadian Journal of Ophthalmology. Journal Canadien d'Ophtalmologie 48(2): 99, 2013

Management of childhood epiphora. British Journal of Ophthalmology 89(9): 1123-1126, 2005

Lacrimal drainage function. 2. The fluorescein dye disappearance test. American Journal of Ophthalmology 74(1): 160-162, 1972

The role of nasolacrimal intubation in the management of childhood epiphora. Eye 7: 760-762, 1993

Reliability of fluorescein dye disappearance test in assessment of adults with nasolacrimal duct obstruction. Ophthalmic Plastic and Reconstructive Surgery 29(3): 167-169, 2013

Assessment of tear drainage by fluorescein dye disappearance test after experimental canalicular obstruction. Acta Ophthalmologica. 71(1): 69-72, 1993

Significance of the fluorescein dye disappearance test (FDDT) in the removal of the silicone cannula and prognosis in congenital lacrimal duct obstruction. Ceska a Slovenska Oftalmologie 59(1): 45-51, 2003

Efficacy of probing for children with congenital nasolacrimal duct obstruction: a retrospective study using fluorescein dye disappearance test and lacrimal sac echography. Graefe's Archive for Clinical and Experimental Ophthalmology 247(6): 837-846, 2009

Screening test for pancreatic function simplification of the fluorescein di laurate test by serum fluorescein determinations. Journal of Clinical Chemistry & Clinical Biochemistry 19(8): 745-746, 1981

The natural history of epiphora in childhood. Eye 12: 669-671, 1998