EurekaMag.com logo
+ Site Statistics
References:
52,725,316
Abstracts:
28,411,598
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

The value of transvaginal ultrasonographic examination of the uterine cervix in predicting preterm delivery in patients with preterm premature rupture of membranes


Ultrasound in Obstetrics & Gynecology 11(1): 23-29
The value of transvaginal ultrasonographic examination of the uterine cervix in predicting preterm delivery in patients with preterm premature rupture of membranes
The objective of this study was to compare the value of ultrasonographic assessment of the uterine cervix and amniotic fluid tests in the prediction of the interval from admission to delivery in patients with preterm premature rupture of membranes. Ninety-two patients admitted to the hospital for preterm premature rupture of membranes between 24 and 32 weeks of gestation underwent both transabdominal amniocentesis and transvaginal ultrasonographic evaluation of the uterine cervix. Amniotic fluid analyses included cultures for aerobic and anaerobic bacteria, mycoplasmas and ureaplasmas, white blood cell count and glucose and interleukin-6 determinations. The ultrasonographic variables evaluated were cervical length, presence of funneling and cervical index ((funnel length + 1)/cervical length). The outcome measure was the interval from admission to delivery. The median interval from admission to delivery was 4.5 days (range 0-36). An abnormal uterine cervix was associated with a short time interval (cervical length < or = 20 mm, median 2 days, range 0-14 vs. median 6 days, range 0-36; p < or = 0.0001; presence of funneling, median 3 days, range 1-31 vs. median 8 days, range 0-36; p < or = 0.001; cervical index > 0.50, median 2 days, range 0-7 vs. median 8 days, range 1-36; p < or = 0.0001). However, interleukin-6 concentration in the amniotic fluid was the best predictor of the interval from admission to delivery when compared to the ultrasonographic indices and to all the amniotic variables considered. Moreover, when a multiple model was applied, the cervical index significantly and independently improved the performance of interleukin-6 in the prediction of the interval from admission to delivery. These data suggest that the combined use of the amniotic fluid interleukin-6 assay and the cervical index in patients with preterm premature rupture of membranes provides a good prediction of the interval from admission to delivery, thus identifying a subgroup of patients at high risk of imminent delivery.


Accession: 047761106

PMID: 9511192

DOI: 10.1046/j.1469-0705.1998.11010023.x



Related references

The value of fetal fibronectin in cervical and vaginal secretions and of ultrasonographic examination of the uterine cervix in predicting premature delivery for patients with preterm labor and intact membranes. American Journal of Obstetrics & Gynecology 175(5): 1146-1151, 1996

Ultrasonographic examination of the uterine cervix is better than cervical digital examination as a predictor of the likelihood of premature delivery in patients with preterm labor and intact membranes. American Journal of Obstetrics & Gynecology 171(4): 956-964, 1994

Transvaginal ultrasound of the cervix identifies impending delivery in patients with preterm premature rupture of membranes. American Journal of Obstetrics & Gynecology 184(1): S50, January, 2001

Is transvaginal ultrasound a better predictor of preterm premature rupture of membranes or spontaneous preterm delivery in multiple gestations?. American Journal of Obstetrics & Gynecology 189(6 Supplement): S240, September, 2003

Sonographic examination of the uterine cervix is a better predictor of the likelihood of preterm delivery than digital examination of the cervix in preterm labor with intact membranes. American Journal of Obstetrics & Gynecology 170(1 PART 2): 296, 1994

Increased levels of interleukin-6 in cervical secretions and assessment of the uterine cervix by transvaginal ultrasonography predict preterm premature rupture of the membranes. Fetal Diagnosis and Therapy 18(2): 98-104, 2003

Usefulness of maternal serum C-reactive protein with vaginal Ureaplasma urealyticum as a marker for prediction of imminent preterm delivery and chorioamnionitis in patients with preterm labor or preterm premature rupture of membranes. Journal of Perinatal Medicine 43(4): 409-415, 2016

Value of amniotic fluid IL-8 and Annexin A2 in prediction of preterm delivery in preterm labor and preterm premature rupture of membranes. Journal of Reproductive Medicine 59(3-4): 154-160, 2014

Length of the uterine cervix by transvaginal ultrasonography in pregnant women with preterm rupture of membranes. Revista Brasileira de Ginecologia e Obstetricia 26(2): 147-151, 2004

Does transvaginal ultrasound of the cervix predict preterm premature rupture of membranes in a high-risk population?. Ultrasound in Obstetrics & Gynecology 18(3): 223-227, 2001