+ Site Statistics
References:
52,654,530
Abstracts:
29,560,856
PMIDs:
28,072,755
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Transfer of resistance to 3rd generation cephalosporins and aztreonam in strains of Klebsiella pneumoniae producing extended spectrum beta-lactamases



Transfer of resistance to 3rd generation cephalosporins and aztreonam in strains of Klebsiella pneumoniae producing extended spectrum beta-lactamases



Epidemiologie, Mikrobiologie, Imunologie 48(1): 21-27



The authors demonstrated the transferability of antibiotic resistance genes in nosocomial strains of Klebsiella pneumoniae, isolated from newborn children at the Paediatric University Hospital in Bratislava. Strains were resistant to cefotaxime, ceftazidime and aztreonam. The determinants of resistance (carbenicillin, cephaloridine, cefotaxime, ceftazidime and aztreonam) were transferred to recipient strains of Escherichia coli K-12 and Proteus mirabilis P-38. The transfer of resistance determinant from donor strains was demonstrated by the analysis of the resistance spectrum in transconjugant clones of recipient strains by the method of indirect selection. The ability of production of extended spectrum beta-lactamases (ESBL) was demonstrated by the double disc diffusion test. Synergy between clavulanate and cefotaxime, clavulanate and ceftazidime and/or clavulanate and aztreonam indicated production of ESBL by these strains.

(PDF emailed within 1 workday: $29.90)

Accession: 047815496

Download citation: RISBibTeXText

PMID: 11038673


Related references

Transferable resistance to 3rd generation cephalosporins and aztreonam in strains of Klebsiella pneumoniae producing beta-lactamases with an extended spectrum (ESBL). Epidemiologie Mikrobiologie Imunologie 48(1): 21-27, 1999

Impact of third-generation cephalosporins restriction on the control of an extended-spectrum beta-lactamases producing Klebsiella pneumoniae outbreak in ICU. Abstracts of the Interscience Conference on Antimicrobial Agents & Chemotherapy 36(0): 222, 1996

Increased serum resistance in Klebsiella pneumoniae strains producing extended-spectrum beta-lactamases. Antimicrobial Agents and ChemoTherapy 48(9): 3477-3482, 2004

Novel extended spectrum beta lactamase tem 22 in klebsiella pneumoniae conferring higher resistance to aztreonam than to extended spectrum cephalosporins. Program & Abstracts of the Interscience Conference on Antimicrobial Agents & Chemotherapy 32: 322, 1992

Novel, plasmid-encoded, TEM-derived extended-spectrum beta-lactamase in Klebsiella pneumoniae conferring higher resistance to aztreonam than to extended-spectrum cephalosporins. Antimicrobial Agents and ChemoTherapy 37(9): 2020-2023, 1993

Transfer of resistance to oxy-imino-cephalosporins and of extended-spectrum beta-lactamase productions in Klebsiella pneumoniae strains from infected neonates. Zentralblatt für Bakteriologie 288(1): 75-86, 1998

Characterization of Klebsiella pneumoniae strains producing extended spectrum beta-lactamases and AMPC type beta-lactamases isolated from hospitalized patients in Kerman, Iran. Roumanian Archives of Microbiology and Immunology 71(2): 81-86, 2012

Detection of Klebsiella pneumoniae strains producing extended-spectrum beta-lactamases. Abstracts of the General Meeting of the American Society for Microbiology 98: 134, 1998

Prevalence and antimicrobial resistance of extended-spectrum beta-lactamases-producing Escherichia coli and Klebsiella pneumoniae strains isolated in a university hospital in Split, Croatia. International Microbiology 8(2): 119-124, 2005

Effectiveness of cefpirome on Klebsiella pneumoniae strains producing extended spectrum beta-lactamases (ESBL). Epidemiologie Mikrobiologie Imunologie 47(1): 12-14, 1998

Detection of Klebsiella pneumoniae and Escherichia coli strains producing extended-spectrum beta-lactamases. Journal of Clinical Microbiology 32(3): 691-696, 1994

Strains of Klebsiella pneumoniae producing extended spectrum beta-lactamases, isolated from organ recipients. Transplantation Proceedings 43(8): 3128-3129, 2012

Survey of Klebsiella pneumoniae strains producing extended-spectrum beta-lactamases: prevalence of SHV-12 and SHV-2a in Korea. Journal of Clinical Microbiology 36(5): 1446-1449, 1998

Reduced use of third-generation cephalosporins decreases the acquisition of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae. Infection Control and Hospital Epidemiology 25(10): 832-837, 2004

Survey on antibiotic-resistance of extended-spectrum beta-lactamases producing Klebsiella pneumoniae. Zhongguo Kangshengsu Zazhi 29(4): 235-237, 254, 2004