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A novel method for measuring the bending rigidity of model lipid membranes by simulating tethers



A novel method for measuring the bending rigidity of model lipid membranes by simulating tethers



Journal of Chemical Physics 125(20): 204905-204905



The tensile force along a cylindrical lipid bilayer tube is proportional to the membrane's bending modulus and inversely proportional to the tube radius. We show that this relation, which is experimentally exploited to measure bending rigidities, can be applied with even greater ease in computer simulations. Using a coarse-grained bilayer model we efficiently obtain bending rigidities that compare very well with complementary measurements based on an analysis of thermal undulation modes. We furthermore illustrate that no deviations from simple quadratic continuum theory occur up to a radius of curvature comparable to the bilayer thickness.

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Accession: 048096196

Download citation: RISBibTeXText

PMID: 17144738

DOI: 10.1063/1.2372761



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