EurekaMag.com logo
+ Site Statistics
References:
53,623,987
Abstracts:
29,492,080
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Accurate mass measurement for the determination of elemental formula--a tutorial



Accurate mass measurement for the determination of elemental formula--a tutorial



Mass Spectrometry Reviews 25(1): 99-111



The application of accurate mass measurement for the determination of elemental formula has its origin in the 1950s and for many years was only carried out using magnetic sector mass spectrometers. The availability of such measurements was limited due to the cost and complexity of the instrumentation and the need for considerable expertise to acquire and interpret the spectra. In recent years the incredible pace of instrumental development has changed this, particularly with the renaissance of time of flight mass spectrometry. This has resulted in instrumentation capable of making accurate mass measurements in a robust fashion becoming available to most practitioners of (mass spectrometry) MS, without some of the earlier technical challenges and at lower cost. In this review the variety of accurate mass measurement instrumentation and techniques and their relative capabilities are discussed, along with a range of applications requiring the determination of elemental formula.

(PDF same-day service: $19.90)

Accession: 048154187

Download citation: RISBibTeXText

PMID: 16052567

DOI: 10.1002/mas.20058



Related references

Stable isotope incorporation triples the upper mass limit for determination of elemental composition by accurate mass measurement. Journal of the American Society for Mass Spectrometry 11(10): 835-840, 2000

Ultrasonic-assisted enzymatic digestion for total elemental determination and elemental speciation a tutorial. Talanta: 4, 872-884, 2008

Ultrasonic-assisted enzymatic digestion (USAED) for total elemental determination and elemental speciation: a tutorial. Talanta 75(4): 872-884, 2008

Elemental mass spectrometry: a powerful tool for an accurate characterisation at elemental level of quantum dots. Chemical Communications: 3107-3109, 2009

Development of isotope dilution-liquid chromatography/mass spectrometry combined with standard addition techniques for the accurate determination of tocopherols in infant formula. Analytica Chimica Acta 787: 132-139, 2014

Fourier transform ion cyclotron resonance mass spectrometry for the characterisation of kavalactones in the kava plant: elemental formulae confirmation by dual spray accurate mass measurement and structural confirmation by infrared multiphoton dissociation and sustained off-resonance irradiation collision induced dissociation. European Journal of Mass Spectrometry 12(4): 223-233, 2006

Measurement of the top quark mass in the [Formula: see text] and [Formula: see text] channels using [Formula: see text] [Formula: see text] ATLAS data. European Physical Journal. C, Particles and Fields 75(7): 330-330, 2015

Accurate mass measurement by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry. I. Measurement of positive radical ions using porphyrin standard reference materials. Rapid Communications in Mass Spectrometry 24(11): 1629-1635, 2010

Accurate mass measurement by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry. II. Measurement of negative radical ions using porphyrin and fullerene standard reference materials. Rapid Communications in Mass Spectrometry 24(20): 3052-3056, 2010

Simultaneous measurement in mass and mass/mass mode for accurate qualitative and quantitative screening analysis of pharmaceuticals in river water. Journal of Chromatography. A 1256: 80-88, 2012

Flow injection of the lock mass standard for accurate mass measurement in electrospray ionization time-of-flight mass spectrometry coupled with liquid chromatography. Rapid Communications in Mass Spectrometry 17(13): 1383-1388, 2003

Accurate mass measurement at enhanced mass-resolution on a triple quadrupole mass-spectrometer for the identification of a reaction impurity and collisionally-induced fragment ions of cabergoline. Rapid Communications in Mass Spectrometry 17(6): 561-568, 2003

Quantitative determination of total L-carnitine in infant formula, follow-up formula, and raw materials by liquid chromatography with tandem mass spectrometry. Analytical Sciences 30(8): 839-844, 2015

Application of ultra-high-performance liquid chromatography/tandem mass spectrometry for the measurement of vitamin D in infant formula and adult/pediatric nutritional formula: First Action 2011.11. Journal of Aoac International 95(2): 319-321, 2012

Accurate mass determination, quantification and determination of detection limits in liquid chromatography-high-resolution time-of-flight mass spectrometry: challenges and practical solutions. Analytica Chimica Acta 789: 74-82, 2013