+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Aggregation of water-soluble block copolymers in aqueous solutions: recent trends

Aggregation of water-soluble block copolymers in aqueous solutions: recent trends

Advances in Colloid and Interface Science 123-126: 75-96

This review summarizes recent literature and some of our own results on aggregation behavior on water-soluble block copolymers belonging to three different classes viz. hydrophilic-hydrophobic (AB, ABA and BAB) block copolymers, double hydrophilic block copolymers (DHBCs) and ABC triblock copolymers. In the case of amphiphilic copolymers, special attention has been focussed on aggregation of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) triblock copolymers (Pluronics) and their aggregation in aqueous solutions at different temperatures as well as in the presence of various additives. Recent studies based on modern techniques viz. scattering (static and dynamic light scattering and small angle neutron scattering), spectral methods, e.g., fluorescence (static and time resolved), nuclear magnetic resonance and Fourier transform infrared spectroscopies, thermal methods e.g., differential scanning calorimetry and isothermal titration calorimetry, cryotransmission electron microscopy, ultrasonic absorption along with general physical properties like surface tension, viscosity and dye solubilization are summarized. For the DHBCs where one of the blocks is usually a polyion, complex formation by adding oppositely charged ions induces the formation of nanoaggregates. Characterization of such nanoaggregates of polyion complexes of DHBCs and their potential use for incorporation of ionic solutes in the micellar core are reviewed. The formation and characteristics of core-shell-corona micelles of ABC triblock copolymers and their applications as vehicles for controlled drug release are also discussed.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 048199740

Download citation: RISBibTeXText

PMID: 16860770

DOI: 10.1016/j.cis.2006.05.016

Related references

Rheological Properties of Silica Suspensions in Aqueous Solutions of Block Copolymers and Their Water-Soluble Components. Journal of Colloid and Interface Science 241(1): 293-295, 2001

Aggregation behavior of polyether block copolymers with dendritic structure in aqueous solutions. Journal of Dispersion Science and Technology 29(8): 1092-1097, 2008

Dissolution-aggregation behavior of water-soluble nanographites and their adsorptive characteristics for 2-naphthol in aqueous solutions. Journal of Colloid and Interface Science 268(1): 58-62, 2003

The electrostatic co-assembly in non-stoichiometric aqueous mixtures of copolymers composed of one neutral water-soluble and one polyelectrolyte (either positively or negatively charged) block: a dissipative particle dynamics study. Physical Chemistry Chemical Physics 18(24): 16137-16151, 2016

Semipermeable polymer vesicle (PICsome) self-assembled in aqueous medium from a pair of oppositely charged block copolymers: physiologically stable micro-/nanocontainers of water-soluble macromolecules. Journal of the American Chemical Society 128(18): 5988-5989, 2006

Aggregation of rod-coil block copolymers containing rigid polyampholyte blocks in aqueous solution. Journal of the American Chemical Society 129(13): 3832-3833, 2007

Aggregation and self-assembly of amphiphilic block copolymers in aqueous dispersions of carbon nanotubes. Langmuir 24(9): 4625-4632, 2008

Effect of ionic liquids on the aggregation behavior of PEO-PPO-PEO block copolymers in aqueous solution. Journal of Physical Chemistry. B 111(6): 1327-1333, 2007

1H NMR spectroscopic investigations on the micellization and gelation of PEO-PPO-PEO block copolymers in aqueous solutions. Langmuir 23(19): 9596-9605, 2007

Trends in the precipitation and crystallization behavior of supersaturated aqueous solutions of poorly water-soluble drugs assessed using synchrotron radiation. Journal of Pharmaceutical Sciences 104(6): 1981-1992, 2015

Phase behavior of ABC-type triple-hydrophilic block copolymers in aqueous solutions. European Physical Journal. E Soft Matter 39(7): 75, 2016

Rheology of aqueous solutions of polyglycidol-based analogues to pluronic block copolymers. Journal of Physical Chemistry. B 112(7): 1899-1905, 2008

Reversible aggregation of polystyrene-block-poly(2-vinylpyridine)-block-poly(ethylene oxide) block copolymer micelles in acidic aqueous Solutions. Langmuir 21(23): 10783-10790, 2005

Pressure-induced reentrant micellization of amphiphilic block copolymers in dilute aqueous solutions. Journal of Chemical Physics 127(9): 094905, 2007

Supramolecular self-assembly of nonlinear amphiphilic and double hydrophilic block copolymers in aqueous solutions. Macromolecular Rapid Communications 30(18): 1523-1532, 2009