+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Childhood Helicobacter pylori infection, clinical presentations, endoscopic, histologic features and results of treatment

Childhood Helicobacter pylori infection, clinical presentations, endoscopic, histologic features and results of treatment

Journal of the Medical Association of Thailand 86 Suppl 3(): S600-S604

To study childhood Helicobacter pylori infection concerning the clinical presentations, endoscopic, histologic features and results of treatment. A retrospective study conducted at the Gastroenterology and Nutrition Unit, Queen Sirikit National Institute of Child Health (QSNICH) was done from January 1993 to December 2002. All patients presented with recurrent abdominal pain, upper GI bleeding (non-variceal bleeding) chronic vomiting and dyspeptic symptoms who underwent upper GI endoscopy were included in this study. Positive urease test verified by biopsied specimens from the gastric antrum and body and/or finding the organisms from the specimens were the criteria for diagnosis of H. pylori infection. Clinical presentations, endoscopic, histologic features and results of treatment in H. pylori infected cases were described. A total of 144 patients who underwent upper GI endoscopy were included in the study. 22 out of 144 cases proved to be infected by H. pylori. Ages ranged from 2.6 to 14 years (mean age 9 years). The male/female ratio was 1:1.2. Vomiting and epigastric pain were the leading symptoms. Endoscopic findings were divided into inflammation in the stomach 12 cases, both stomach and duodenum 6 cases and duodenal ulcer 4 cases. Nodular hyperplasia of gastric antrum was found in 8 out of 22 cases. Histologic evidence of chronic gastritis was present in 12 cases, chronic gastroduodenitis 6 cases and chronic duodenitis in duodenal ulcer cases. Treatment regimen consisted of one H2 blocker (ranitidine) initially which was changed to omeprazole in 2001 combined with 2 antibiotics (amoxycillin and metronidazole) for 14 days. This study group represented middle and low income groups from around Bangkok and many parts of Thailand. The prevalence of H. pylori infection in the present study was 15.3 per cent which reflects that H. pylori infection is a common health problem in Thailand. However, because this was only a descriptive study, the authors cannot specify the association between symptoms, endoscopic findings, histologic features and disease.

(PDF emailed within 1 workday: $29.90)

Accession: 048507090

Download citation: RISBibTeXText

PMID: 14700155

Related references

Influence of different Helicobacter pylori genotypes upon clinical, endoscopic and morphologic presentations of chronic gastroduodenal pathology in childhood and adolescence. Pediatriya (Moscow) 86(5): 28-32, 2007

Helicobacter pylori infection in children: clinical, endoscopic, and histologic correlations. Journal of Pediatric Gastroenterology and Nutrition 14(4): 420-425, 1992

Helicobacter pylori infection in 409 pediatric patients with dyspepsia or immunodeficiency clinical and endoscopic features. Gastroenterology 102(4 PART 2): A79, 1992

Endoscopic and clinical features of gastric ulcers in Japanese patients with or without Helicobacter pylori infection who were using NSAIDs or low-dose aspirin. Journal of Gastroenterology 47(8): 904-911, 2013

Pathology of Helicobacter pylori infection: Histologic features. Stomach & Intestine 31(8): 945-950, 1996

Anti-Helicobacter pylori immunoglobulin G (IgG) and IgA antibody responses and the value of clinical presentations in diagnosis of H. pylori infection in patients with precancerous lesions. World Journal of Gastroenterology 9(4): 755-758, 2003

Endoscopic and histologic findings of gastric mucosa in children with and without Helicobacter pylori infection. Helicobacter 8(4): 459, August, 2003

Endoscopic and histologic analysis of gastric mucosa-associated lymphoid tissue in children with Helicobacter pylori infection. Journal of Pediatric Gastroenterology and Nutrition 57(3): 298-304, 2014

Endoscopic, histologic and microbiologic evaluation of upper abdominal pain with special reference to Helicobacter pylori infection. Indian Pediatrics 33(11): 905-909, 1996

Helicobacter pylori infection in childhood revealed by hematemesis: endoscopic and pathologic patterns. La Tunisie Medicale 85(11): 930-934, 2009

Clinical, endoscopic and histologic aspects of chronic Helicobacter pylori gastritis in Côte d'Ivoire: study of 102 patients. Bulletin de la Societe de Pathologie Exotique 94(1): 5-7, 2001

Clinical and histologic predictors of Helicobacter pylori infection recurrence. Journal of Clinical Gastroenterology 31(1): 38-41, 2000

Consideration of Helicobacter pylori infection in childhood: Immune response, endoscopic and morphological findings. Acta Paediatrica Japonica 37(5): 551-556, 1995

Diagnostic utility of invasive tests and serology for the diagnosis of Helicobacter pylori infection in different clinical presentations. Archives of Medical Research 37(1): 123-128, 2005