+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Clinical study of lymph node metastatic pattern of thoracic esophageal squamous carcinoma



Clinical study of lymph node metastatic pattern of thoracic esophageal squamous carcinoma



Di 1 Jun Yi Da Xue Xue Bao 25(5): 573-574



To analyze the patterns of lymph node metastases of thoracic esophageal carcinoma and define the adequate range of lymph node dissection. The clinical data of 217 patients with esophageal carcinoma undergoing radical surgical resection of the lymph nodes in three regions were retrospectively analyzed. Lymph node metastases were found in 136 of the 217 patients (62.6%) and skip metastases of the lymph nodes in 12 patients (5.5%). In 3 989 lymph nodes desected, metastases were identified in 454 lymph nodes (11.38%). The rates of lymph node metastasis were 31.7%, 21.2% and 12.1% in the neck, thoracic mediastinum and abdominal cavity, respectively, in upper thoracic esophageal carcinoma, 21.9%, 30.5% and 15.6% in middle thoracic carcinoma, and 9.75%, 12.7% and 34.5% in lower thoracic carcinoma. The degree of tumor differentiation, depth of tumor invasion and lymphatic vessel invasion were factors influencing lymph node metastases (P<0.05). Because of the upward, downward and skip metastasis of esophageal carcinoma cells to the lymph nodes, the operable patients with thoracic esophagus carcinoma should receive radical desection of the lymph nodes in the 3 regions to promote the patients' survival.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 048557287

Download citation: RISBibTeXText

PMID: 15897141


Related references

Impact of the pattern of lymph node metastasis on the clinical target volume in radiotherapy for thoracic esophageal squamous cell carcinoma. Zhonghua Zhong Liu Za Zhi 32(3): 225-228, 2010

Precise delineation of clinical target volume for crossing-segments thoracic esophageal squamous cell carcinoma based on the pattern of lymph node metastases. Journal of Thoracic Disease 7(12): 2313-2320, 2015

Pattern of lymph node metastases and its implication in radiotherapeutic clinical target volume in patients with thoracic esophageal squamous cell carcinoma: A report of 1077 cases. RadioTherapy and Oncology 95(2): 229-233, 2010

Pattern of lymph node metastasis in thoracic esophageal squamous cell carcinoma with poor differentiation. Molecular and Clinical Oncology 8(6): 760-766, 2018

Analysis of early lymph node metastasis pattern and prognosis in thoracic esophageal squamous cell carcinoma. Zhonghua Wei Chang Wai Ke Za Zhi 17(9): 884-887, 2014

The pattern of cervical lymph node metastasis in thoracic esophageal squamous cell carcinoma may affect the target decision for definitive radiotherapy. RadioTherapy and Oncology 123(3): 382-386, 2017

A strategy for supraclavicular lymph node dissection using recurrent laryngeal nerve lymph node status in thoracic esophageal squamous cell carcinoma. Annals of Thoracic Surgery 95(6): 1930-1937, 2013

Cervical lymph node metastasis classified as regional nodal staging in thoracic esophageal squamous cell carcinoma after radical esophagectomy and three-field lymph node dissection. Bmc Surgery 14: 110, 2014

Clinical outcomes and selection conditions of three-field lymph node dissection for thoracic esophageal squamous cell carcinoma. Zhonghua Zhong Liu Za Zhi 34(3): 212-215, 2012

Prediction of lymph node metastatic status in superficial esophageal squamous cell carcinoma using an assessment model combining clinical characteristics and pathologic results: A retrospective cohort study. International Journal of Surgery 66: 53-61, 2019

Comparison of survival and recurrence pattern between two-field and three-field lymph node dissections for upper thoracic esophageal squamous cell carcinoma. Journal of Thoracic Oncology 5(5): 707-712, 2010

Can common hepatic artery lymph node dissection be safely omitted in surgery for clinical T1N thoracic esophageal squamous cell carcinoma?. 2012

Experimental study of lymph node metastasis in thoracic esophageal carcinoma--regarding lymph node metastasis and changes in lymphatic flow by ultrafine charcoal in rabbit esophageal carcinoma model. Nihon Geka Gakkai Zasshi 93(5): 462-474, 1992

Clinical study on lymph node metastatic recurrence in patients with N0 esophageal squamous cell cancer. Diseases of the Esophagus 24(3): 182-188, 2011

Can common hepatic artery lymph node dissection be safely omitted in surgery for clinical T1N0 thoracic esophageal squamous cell carcinoma?. Diseases of the Esophagus 26(3): 272-275, 2013