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Section 49

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References:

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Mortazavi, J.; Farahmand, F.; Behzadipour, S.; Yeganeh, A.; Aghighi, M. 2018: A patient specific finite element simulation of intramedullary nailing to predict the displacement of the distal locking hole. Medical Engineering and Physics 55: 34-42
Chen, X.; Sun, P.; Liao, D. 2018: A patient-specific haptic drilling simulator based on virtual reality for dental implant surgery. International Journal of Computer Assisted Radiology and Surgery 13(11): 1861-1870
Pandiyan, B.; Merrill, S.J.; Di Bari, F.; Antonelli, A.; Benvenga, S. 2018: A patient-specific treatment model for Graves' hyperthyroidism. Theoretical Biology and Medical Modelling 15(1): 1
Hengartner, M.P. 2018: A Patient´s Personality: A Frequently Ignored but Important Component in General Medical Practice. Praxis 107(12): 641-647
Shen-Wagner, J.; Wagner, M.; Hughes, A. 2018: A Patient's Perspective: Pairing the Stethoscope with POCUS to Evaluate Acute Dyspnea in the Clinic. Southern Medical Journal 111(7): 401-403
Dale, A.M. 1918: A Patient's Protest. Hospital 65(1696): 208
Anonymous 1913: A Patient's Sanatorium Experiences. Hospital 54(1419): 688
Chen, Y.-L.; Yang, L.-S.; Zhang, H.; Sun, S.-H. 2018: A patient suffered from not only MSI-H colon cancer but also adrenal pheochromocytoma. Kaohsiung Journal of Medical Sciences 34(1): 67-69
Ren, H.; Yang, Y.; Gu, C.; Weng, T.; Yang, H. 2018: A Patient Suffering From Neurodegenerative Disease May Have a Strengthened Fractal Gait Rhythm. IEEE transactions on neural systems and rehabilitation engineering: a publication of the IEEE Engineering in Medicine and Biology Society 26(9): 1765-1772
Koole, P.; Zonnenberg, A.J.J.; Mulder, J. 2019: A patient's view on the location of the temporomandibular joint. Cranio: the Journal of Craniomandibular Practice 37(5): 335-338
Marukawa, D.; Murakami, M.; Shimizu, J.; Koga, C.; Yasuyama, H.; Matsumura, T.; Takata, A.; Kameda, C.; Kawabata, R.; Hirota, M.; Noura, S.; Miwa, H.; Hasegawa, J. 2018: A Patient Underwent Pancreaticoduodenectomy with Reconstruction of Replaced Right Hepatic Artery. Gan to Kagaku Ryoho. Cancer and ChemoTherapy 45(1): 166-168
Rübsam, A.; Pahlitzsch, M.; Pleyer, U. 2019: A patient who lost the sense of hearing and sight. Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 116(5): 462-466
Maruyama, M.; Nakamura, T.; Soeno, T.; Shimazu, M.; Tsutsui, A.; Tajima, H.; Miura, H.; Yamanashi, T.; Satoh, T.; Kumamoto, Y.; Watanabe, M. 2017: A Patient Who Underwent Resection of Liver Metastases after Receiving Systemic Chemotherapy for Advanced Rectal Cancer and Multiple Liver Metastases. Gan to Kagaku Ryoho. Cancer and ChemoTherapy 44(12): 1541-1543
Dindar, G.ök.; Sezikli, M.; Çam, İs.; Turgut, H.T. 2018: A patient with abdominal pain and obstructive jaundice. Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology 29(2): 233-236
Hahn, M.; Roll, S.C. 2016: A patient with acute mania after discontinuation of lithium. Medizinische Monatsschrift für Pharmazeuten 39(9): 385-387
Ota, S.; Haruyama, T.; Ishihara, M.; Natsume, M.; Fukasawa, Y.; Sakamoto, T.; Tanzawa, S.; Usui, R.; Honda, T.; Ichikawa, Y.; Watanabe, K.; Sasajima, Y.; Seki, N. 2018: A Patient with Advanced Gastric Cancer Who Achieved a Long-Term Prognosis by Early Diagnosis of Sister Mary Joseph's Nodule. Case Reports in Oncology 11(1): 11-16
Maher, M.; Roncaroli, F.; Mendoza, N.; Meeran, K.; Canham, N.; Kosicka-Slawinska, M.; Bernhard, B.; Collier, D.; Drummond, J.; Skordilis, K.; Tufton, N.; Gontsarova, A.; Martin, N.; Korbonits, M.ár.; Wernig, F. 2018: A patient with a germline SDHB mutation presenting with an isolated pituitary macroprolactinoma. Endocrinology Diabetes and Metabolism Case Reports 2018
Okumura, A.; Maruyama, K.; Shibata, M.; Kurahashi, H.; Ishii, A.; Numoto, S.; Hirose, S.; Kawai, T.; Iso, M.; Kataoka, S.; Okuno, Y.; Muramatsu, H.; Kojima, S. 2018: A patient with a GNAO1 mutation with decreased spontaneous movements, hypotonia, and dystonic features. Brain and Development 40(10): 926-930
Simabukuro, M.M.; Freitas, C.H.d.A.; Castro, L.H.M. 2015: A patient with a long history of relapsing psychosis and mania presenting with anti-NMDA receptor encephalitis ten years after first episode. Dementia and Neuropsychologia 9(3): 311-314
Oyakawa, T.; Muraoka, N.; Iida, K.; Kusuhara, M.; Naito, T. 2018: A Patient with a Massive Single Cardiac Metastasis of Lung Adenocarcinoma, Diagnosed via a Biopsy. Internal Medicine 57(11): 1637-1640
Au, E.Y.L.; Rosa Duque, J.S.; Lau, C.S.; Chan, E. 2018: A patient with anaphylaxis to diphenhydramine without cross-reactivity to loratadine. Journal of Allergy and Clinical Immunology. in Practice 6(3): 1061-1063
Dillon, J.L.; Cervinski, M.A. 2018: A Patient with an Unexpectedly Low Hemoglobin A1c. Clinical Chemistry 64(8): 1263-1264
Dong, D.; Zhu, T.; Yang, X.; Zhu, J. 2018: A patient with an unusual cyst of the inter-atrial septum and atrial sepal defect. Echocardiography 35(6): 876-879
Valerio, M.; López-Medrano, F.; Regalado-Artamendi, I.; Muñoz, P.; Aguado, J.M.; Bouza, E. 2018: A patient with a rapidly lethal pneumonia after a visit to a touristic area in rural Leon (Spain). Revista Espanola de Quimioterapia: Publicacion Oficial de la Sociedad Espanola de Quimioterapia 31(4): 367-373
Miyamoto, K.; Matsuoka, N.; Ono, S.; Nakamura, S.; Nagaya, K.; Asai, N.; Nishikawa, K.; Ito, Y.; Imai, H. 2019: A patient with arteriovenous fistula of simultaneously performed anastoplasty for excessive blood flow and graft bypass to secure an outflow tract. Journal of Vascular Access 20(1_Suppl): 80-83
Turner, D. 2018: A patient with autonomic imbalance: Treating symptomatic neurogenic orthostatic hypotension. Nurse Practitioner 43(6): 18-22
Watanabe, A.; Fukunari, H.; Kawai, Y.; Aoki, M.; Saito, S.; Umebayashi, Y.; Shitara, K.; Hayashi, T.; Watanabe, G.; Ajioka, H. 2017: A Patient with Basaloid Carcinoma of the Esophagus Removed Surgically after Pre-Operative Chemotherapy who Developed TTP during Post-Operative Chemotherapy. Gan to Kagaku Ryoho. Cancer and ChemoTherapy 44(12): 1110-1113
Ha, J.; Kim, B.; Hahn, S.; Lee, S.-T.; Lyu, C.J.; Choi, J.R. 2018: A patient with B-cell acute lymphoblastic leukemia with PAX5-ETV6 rearrangement with dic(9;12)(p13;p13) identified by chromosomal microarray. Annals of Hematology 97(8): 1505-1507
Lim, S.-Y.; Tan, A.H.; Ahmad-Annuar, A.; Schneider, S.A.; Bee, P.C.; Lim, J.L.; Ramli, N.; Idris, M.I. 2018: A Patient with Beta-Propeller Protein-Associated Neurodegeneration: Treatment with Iron Chelation Therapy. Journal of Movement Disorders 11(2): 89-92
Klaphake, S.; van Dooren, M.F.; Senden, R.E.M.; Hoogeboom, A.J.M.; Wolvius, E.B.; Koudstaal, M.J. 2018: A patient with chromosome 18p deletion and congenital hypoglossia. Clinical Dysmorphology 27(2): 46-48
Gonzalez-Olivares, M.; Moreno-Torres, A.; Navarro-Vidal, B.; Cordoba, S.; Garrido-Rios, A.A.; Ruiz-Giardin, J.M.; Borbujo, J. 2018: A patient with chronic labial oedema and nodular palatal lesions. Clinical and Experimental Dermatology 43(4): 481-484
Sun, Y.; Li, X.; Li, L.; Liu, H.; Xu, Q.; Liu, B. 2017: A patient with chronic myeloid leukemia and situs inversus totalis: A case report. Oncology Letters 14(6): 7425-7430
Wagener, E.D.A.; Souma, N.; Hodakowski, A.; Martinez, C.; Fox, P.; Mehta, R.; O'Brien, M.J.; Bolon, M.; Kulik, L.; Yang, G.-Y.; Isakova, T.; Block, G.A.; Cheung, A.K.; Flessner, M.F.; Fried, L.; Gassman, J.J.; Ix, J.H.; Kusek, J.W.; Raj, D.; Raphael, K.L.; Sprague, S.M.; Wolf, M. 2018: A Patient with CKD Develops Cholestatic Liver Injury During a Clinical Trial. Kidney International Reports 3(1): 5-10
Meng, Z.; Chen, P.; Zang, F.; Liu, Y.; Xu, X.; Su, Y.; Chen, J.; Lin, L.; Zhang, L.; Zhang, T. 2018: A patient with classic biphasic pulmonary blastoma harboring CD74-ROS1 fusion responds to crizotinib. Oncotargets and Therapy 11: 157-161
Wesselius, R.; Schotman, M.; Schotman, M.; Pereira, A.M. 2017: A Patient (46XX) With Congenital Adrenal Hyperplasia and Prostate Cancer: A Case Report. Journal of the Endocrine Society 1(9): 1213-1216
Sarkar, R.; Paul, R.; Roy, D.; Saha, A.; Sau, T.J.; Mondal, J. 2017: A Patient with Dilated Cardiomyopathy and Portal Hypertension: which Beta-Blocker to Use?. Journal of the Association of Physicians of India 65(9): 107
Hassan, M.; Rana, M.; Rahman, N.M. 2018: A Patient with Effusion Undergoing Pleural Biopsy. Chest 154(2): E37-E39
Nanaura, H.; Kataoka, H.; Shima, S.; Iwasa, N.; Eura, N.; Sugie, K.; Mutoh, T.; Ueno, S. 2018: A Patient with Encephalomyeloradiculoneuropathy Exhibiting a Relapsing-Remitting Clinical Course: Correlation of Serum and Cerebrospinal Fluid Anti-Neutral Glycosphingolipids Antibodies with Clinical Relapse. Frontiers in Neurology 9: 206
Van Geffen, M.W.L.; van Niekerk, J.M.; Posthouwer, D. 2018: A patient with fever and skin lesions after vacation in South Africa. Netherlands Journal of Medicine 76(3): 134
Niyyar, V.D.; Lok, C.E. 2018: A Patient with Hemodialysis Access Problems. Clinical Journal of the American Society of Nephrology: Cjasn 13(9): 1410-1412
Thurman, J.M. 2018: A Patient with Hemolytic Uremic Syndrome and Kidney Failure. Clinical Journal of the American Society of Nephrology: Cjasn 13(6): 933-936
Sridharan, M.; Highsmith, W.E.; Kurtin, P.J.; Zimmermann, M.T.; Theis, J.D.; Dasari, S.; Dingli, D. 2018: A Patient with Hereditary ATTR and a Novel AGel p.Ala578Pro Amyloidosis. Mayo Clinic Proceedings 93(11): 1678-1682
Hasebe, H. 2018: A Patient with Left Bundle Branch Block and Persistent Atrial Fibrillation Treated with Cardiac Catheter Ablation and Pharmacologic Cardiac Resynchronization Therapy without the use of an Implantable Cardiac Device. American Journal of Case Reports 19: 123-127
Sato, M.; Kishida, D.; Miyazaki, D.; Sekijima, Y. 2019: A Patient with Limbic Encephalitis Associated with Anti-leucine-rich Glioma-inactivated 1 (LGI1) Antibody Presenting with Slowly Progressive Cognitive Impairment and Fluctuating Striatal Lesions. Internal Medicine 58(2): 287-291
Koike, T.; Kanno, T.; Karino, M.; Sekine, J. 2017: A Patient with Lower Lip Verrucous Carcinoma Treated with a Tongue Flap for Functional and Esthetic Reconstruction. Gan to Kagaku Ryoho. Cancer and ChemoTherapy 44(12): 1936-1938
Ikeda, Y.; Kokai, S.; Ono, T. 2018: A patient with mandibular deviation and 3 mandibular incisors treated with asymmetrically bent improved superelastic nickel-titanium alloy wires. American Journal of Orthodontics and Dentofacial Orthopedics: Official Publication of the American Association of Orthodontists its Constituent Societies and the American Board of Orthodontics 153(1): 131-143
Matrone, A.; Brancatella, A.; Marchetti, P.; Vasile, E.; Boggi, U.; Elisei, R.; Cetani, F.; Marcocci, C.; Vitti, P.; Latrofa, F. 2018: A patient with MEN1 and end-stage chronic kidney disease due to Alport syndrome: Decision making on the eligibility of transplantation. Molecular and Clinical Oncology 8(3): 449-452
Tchernev, G.; Philipov, S.; Chokoeva, A.Atanasova.; Wollina, U.; Lotti, T.; Lozev, I.; Yungareva, I.; Maximov, G.Konstantinov. 2018: A Patient with Multiple Keratinocytic Cancers (MKC): Uncommon Presentation in a Bulgarian Patient. Open Access Macedonian Journal of Medical Sciences 6(1): 120-122
Kotan, D.; Alemdar, M.; Köksal, S.A.ça. 2017: A Patient with Neuro-Behçet's Syndrome Presenting with Peripheral Nerve Involvement. Noro Psikiyatri Arsivi 54(4): 376-378
Lopez Luis, B.A.; Antiga-López, F.J.; Ortiz-Brizuela, E. 2018: A patient with neutropenic fever and intraosseous gas. Qjm: Monthly Journal of the Association of Physicians 111(10): 751-752
Akashi, M.; Tajiri, K.; Wada, A.; Tsuneyama, K.; Kawai, K.; Yasumura, S.; Minemura, M.; Takahara, T.; Sugiyama, T. 2018: A Patient with Non-alcoholic Steatohepatitis Complicated by Multiple Myeloma. Internal Medicine 57(14): 2013-2018
Jungmann, S.; Ludwig, W.-D.; Schönfeld, N.; Blum, T.-G.; Großwendt, C.; Boch, C.; Rehbock, B.; Griff, S.; Schmittel, A.; Bauer, T.T. 2017: A Patient with Non-Hodgkin Lymphoma and Nonspecific Interstitial Pneumonia during Ibrutinib Therapy. Case Reports in Oncological Medicine 2017: 5640186
Patel, K.H.; Reddy, A.V.Guarava.; Eachempati, K.; Muralidhar, S.; Jungele, A. 2018: A Patient with Osteoarthritis Knee and Prior Patella Fracture: Single Stage Fixation and Total Knee Arthroplasty: A Case Report. Journal of Orthopaedic Case Reports 8(1): 67-70
Curtis, S.A.; Curtis, B.R.; Lee, A.I.; Hendrickson, J.E.; Lacy, J.; Podoltsev, N.A. 2018: A patient with oxaliplatin immune-induced syndrome (OIIS) who also developed leucovorin and palonosetron-associated thrombocytopenia. Hematology 23(7): 429-432
Tay, S.H.; Wong, A.S.; Jeyasekharan, A.D. 2018: A patient with pembrolizumab-induced fatal polymyositis. European Journal of Cancer 91: 180-182
Espinola-Klein, C. 2017: A patient with peripheral artery disease. Medizinische Monatsschrift für Pharmazeuten 40(3): 107-108
Akutsu, Y.; Shirai, K.; Takei, A.; Goto, Y.; Aoyama, T.; Watanabe, A.; Imamura, M.; Enokizono, T.; Ohto, T.; Hori, T.; Suzuki, K.; Hayashi, M.; Masumoto, K.; Inoue, K. 2018: A patient with peripheral demyelinating neuropathy, central dysmyelinating leukodystrophy, Waardenburg syndrome, and severe hypoganglionosis associated with a novel SOX10 mutation. American Journal of Medical Genetics. Part a 176(5): 1195-1199
Capps, J.; Nwosu, N.; Baksi, S.; Khalid, S. 2018: A patient with persistent consolidation and a pulmonary mass. Journal of the Royal College of Physicians of Edinburgh 48(2): 124-126
Broccoli, A.; Nanni, L.; Stefoni, V.; Agostinelli, C.; Argnani, L.; Cavo, M.; Zinzani, P.Luigi. 2018: A patient with plasmablastic lymphoma achieving long-term complete remission after thalidomide-dexamethasone induction and double autologous stem cell transplantation: a case report. Bmc Cancer 18(1): 645
Alfishawy, M.; Ali, H.; Daoud, A. 2018: A patient with polycystic kidney disease, hepatic cysts and atrial myxoma. Saudi Journal of Kidney Diseases and Transplantation: An Official Publication of the Saudi Center for Organ Transplantation Saudi Arabia 29(3): 723-727
Dekeyzer, S. 2017: A Patient with Rapidly Progressive Proptosis. Journal of the Belgian Society of Radiology 101(1): 30
Ibrahim, W.; Nakia, H.; Stephen, M.; Bruce, S.; Bryan, W.; William, P. 2019: A Patient With Remote Heparin-Induced Thrombocytopenia and Antiphospholipid Syndrome Requiring Cardiopulmonary Bypass: Do Current Guidelines Apply?. Seminars in Cardiothoracic and Vascular Anesthesia 23(2): 256-260
Ghosn, Y.; Kamareddine, M.H.; Adem, C.; Jabbour, R. 2018: A Patient with Schizencephaly and Agenesis of Corpus Callosum with no Neurological Deficits. Journal of Neurosciences in Rural Practice 9(3): 404-405
Furukawa, H.; Nakamuro, M.; Nakano, H.; Kondo, Y.; Ishikawa, K.; Okubo, Y.; Imano, M.; Yasuda, T.; Kimura, Y.; Imamoto, H.; Shinkai, M.; Yasuda, A.; Shiraishi, O.; Iwama, M.; Kato, H. 2017: A Patient with Scirrhous Gastric Cancer Diagnosed and Resected Subsequently by Laparotomy Examination Due to Difficulty to Take Cancer Specimen by Endoscopic Biopsy. Gan to Kagaku Ryoho. Cancer and ChemoTherapy 44(12): 1077-1079
Cavalcante Pita Neto, I.; Martins Pereira Lucena Franco, J.éf.; Chaves Moreno, E.; Pita, P.; Aurelio Lucchesi Sandrini, F.; Gomes de Alencar Gondim, D. 2018: A Patient with Severe Lower Face Degloving Injury. Journal of Craniofacial Surgery 29(6): E608-E610
Dekeyzer, S. 2017: A Patient with Slowly Progressive Proptosis. Journal of the Belgian Society of Radiology 101(1): 29
Elvenes, J.; Fismen, S.; Lynghaug, G.M.; Bakland, G. 2018: A patient with spondylarthropathy treated with TNF-α inhibitors presenting with clinical findings suspicious of metastatic cancer disease. Rheumatology 57(12): 2246-2248
Chung, H.Jin.; Koh, M.Ju.; Kim, C-Hoon.; Chang, J.Hyun. 2018: A Patient With Submerged Sinonasal Angiosarcoma After Resection of Underlying Organizing Hematoma. Journal of Craniofacial Surgery 29(3): 645-647
Wagner, M.; Raza, W.; Esteves, A.R.; Ryals, S.; Berry, R. 2018: A Patient with Suspicious Oxygen Desaturations at Sleep Onset. Journal of Clinical Sleep Medicine: Jcsm: Official Publication of the American Academy of Sleep Medicine 14(8): 1435-1436
Hosseini, J.; Rahavian, A.; Soleimanzadeh, F. 2019: A Patient with Third Corpus Cavernosum, Severe Penile Ventral Deviation and Partial Peno-scrotal Transposition: First Worldwide Report. Urologia Internationalis 102(4): 492-494
Meštrović, A.; Žaja, I.; Ardalić, Žarko.; Vrebalov-Cindro, P.; Šustić, I.; Puljiz, M.; Bratanić, A.; Bonacin, D. 2018: A Patient with Ulcerative Colitis Complicated by Systemic Vein Thrombosis. Case Reports in Gastroenterology 12(2): 322-326
Figueroa-Jiménez, L.A.; Cabrera-Márquez, A.L.; Báez-Díaz, L.; Cáceres-Perkins, W. 2016: A patient with white blood cell counts more than a million: a diagnostic and therapeutic challenge. El Bisturi 2016: 12-16
Zhao, F.; Tian, W.; Zeng, M.; Xia, J.; Hu, H.; Hao, X.; Han, L.; Liu, H.; He, Y.; Zhu, X.; Liang, L.; Ao, R.; Wei, M.; Deng, L.; Wei, Y. 2017: Apatinib alone or combined with radiotherapy in metastatic prostate cancer: Results from a pilot, multicenter study. Oncotarget 8(67): 110774-110784
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Qiu, H.; Li, J.; Liu, Q.; Tang, M.; Wang, Y. 2018: Apatinib, a novel tyrosine kinase inhibitor, suppresses tumor growth in cervical cancer and synergizes with Paclitaxel. Cell Cycle 17(10): 1235-1244
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Fang, S.; Zhang, M.; Wei, G.; Lu, K.-H. 2018: Apatinib as a third- or further- line treatment in patients with advanced NSCLC harboring wild-type EGFR. Oncotarget 9(6): 7175-7181
Li, F.; Tao, H. 2018: Apatinib as Salvage Therapy for Heavily Pretreated SCLC. Zhongguo Fei Ai Za Zhi 21(7): 565-570
Li, F.; Liao, Z.; Zhang, C.; Zhao, J.; Xing, R.; Teng, S.; Zhang, J.; Yang, Y.; Yang, J. 2018: Apatinib as targeted therapy for sarcoma. Oncotarget 9(36): 24548-24560
Lan, C.-Y.; Wang, Y.; Xiong, Y.; Li, J.-D.; Shen, J.-X.; Li, Y.-F.; Zheng, M.; Zhang, Y.-N.; Feng, Y.-L.; Liu, Q.; Huang, H.-Q.; Huang, X. 2018: Apatinib combined with oral etoposide in patients with platinum-resistant or platinum-refractory ovarian cancer (AEROC): a phase 2, single-arm, prospective study. LANCET. Oncology 19(9): 1239-1246
Liang, L.; Wang, L.; Zhu, P.; Xia, Y.; Qiao, Y.; Hui, K.; Hu, C.; Ren, Y.; Jiang, X. 2017: Apatinib concurrent gemcitabine for controlling malignant ascites in advanced pancreatic cancer patient: A case report. Medicine 96(47): E8725
Hu, T.; Liu, C.; Li, Q.; Xiong, J.; Ma, Y.; Wu, G.; Zhao, Y. 2018: Apatinib + CPT-11 + S-1 for treatment of refractory brain metastases in patient with triple-negative breast cancer: Case report and literature review. Medicine 97(15): E0349
Deng, M.; Zha, J.; Jiang, Z.; Jia, X.; Shi, Y.; Li, P.; Chen, X.L.; Fang, Z.; Du, Z.; Xu, B. 2018: Apatinib exhibits anti-leukemia activity in preclinical models of acute lymphoblastic leukemia. Journal of Translational Medicine 16(1): 47
Yang, C.; Feng, W.; Wu, D. 2018: Apatinib for advanced nonsmall-cell lung cancer: A retrospective case series analysis. Journal of Cancer Research and Therapeutics 14(1): 159-162
Xie, L.; Guo, W.; Wang, Y.; Yan, T.; Ji, T.; Xu, J. 2018: Apatinib for advanced sarcoma: results from multiple institutions' off-label use in China. Bmc Cancer 18(1): 396
Yang, D.; Dai, R.; Zhang, Q.; Fang, P. 2018: Apatinib for heavily treated patients with non-small cell lung cancer: Report of a case series and literature review. Saudi Journal of Biological Sciences 25(5): 888-894
Jin, Z.; Cheng, X.; Feng, H.; Kuang, J.; Yang, W.; Peng, C.; Shen, B.; Qiu, W. 2017: Apatinib Inhibits Angiogenesis Via Suppressing Akt/GSK3β/ANG Signaling Pathway in Anaplastic Thyroid Cancer. Cellular Physiology and Biochemistry: International Journal of Experimental Cellular Physiology Biochemistry and Pharmacology 44(4): 1471-1484
Zheng, B.; Ren, T.; Huang, Y.; Guo, W. 2018: Apatinib inhibits migration and invasion as well as PD-L1 expression in osteosarcoma by targeting STAT3. Biochemical and Biophysical Research Communications 495(2): 1695-1701
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Kong, Y.; Sun, L.; Hou, Z.; Zhang, Y.; Chen, P.; Cui, Y.; Zhu, X.; Song, T.; Li, Q.; Li, H.; Zhang, T.; Qin, L. 2017: Apatinib is effective for treatment of advanced hepatocellular carcinoma. Oncotarget 8(62): 105596-105605
Tian, Y.; Liu, Z.; Zhang, L.; Zhang, J.; Han, X.; Wang, Q.; Cheng, W. 2018: Apatinib-loaded lipid nanobubbles combined with ultrasound-targeted nanobubble destruction for synergistic treatment of HepG2 cells in vitro. Oncotargets and Therapy 11: 4785-4795
Liu, Z.; Ou, W.; Li, N.; Wang, S.-Y. 2018: Apatinib monotherapy for advanced non-small cell lung cancer after the failure of chemotherapy or other targeted therapy. Thoracic Cancer 9(10): 1285-1290
Zhang, H.; Cao, Y.; Chen, Y.; Li, G.; Yu, H. 2018: Apatinib promotes apoptosis of the SMMC-7721 hepatocellular carcinoma cell line via the PI3K/Akt pathway. Oncology Letters 15(4): 5739-5743
Liu, Z.-L.; Jin, B.-J.; Cheng, C.-G.; Zhang, F.-X.; Wang, S.-W.; Wang, Y.; Wu, B. 2017: Apatinib resensitizes cisplatin-resistant non-small cell lung carcinoma A549 cell through reversing multidrug resistance and suppressing ERK signaling pathway. European Review for Medical and Pharmacological Sciences 21(23): 5370-5377
Chen, Y.; Ma, G.; Su, C.; Wu, P.; Wang, H.; Song, X.; Yu, Q.; Zeng, A.; Zhou, S. 2018: Apatinib reverses alectinib resistance by targeting vascular endothelial growth factor receptor 2 and attenuating the oncogenic signaling pathway in echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase fusion gene-positive lung cancer cell lines. Anti-Cancer Drugs 29(10): 935-943
Yang, C.; Qin, S. 2018: Apatinib targets both tumor and endothelial cells in hepatocellular carcinoma. Cancer Medicine 7(9): 4570-4583
Chen, K.; Gao, Y.; Shi, F.; Cao, G.; Bao, J. 2018: Apatinib-treated advanced medullary thyroid carcinoma: a case report. Oncotargets and Therapy 11: 459-463
Yang, L.; Liu, L.; Han, B.; Han, W.; Zhao, M. 2018: Apatinib treatment for KIT- and KDR-amplified angiosarcoma: a case report. Bmc Cancer 18(1): 618
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Ye, C.; Long, Y.; Ji, G.; Li, Q.Q.; Wu, X. 2018: APAtrap: identification and quantification of alternative polyadenylation sites from RNA-seq data. Bioinformatics 34(11): 1841-1849
Hammack, A.; Rihani, R.T.; Black, B.J.; Pancrazio, J.J.; Gnade, B.E. 2018: A patterned polystyrene-based microelectrode array for in vitro neuronal recordings. Biomedical Microdevices 20(2): 48
Hao, T.; Pan, X.; Gu, Z.; Qu, Y.; Weng, H. 2018: A pattern learning-based method for temporal expression extraction and normalization from multi-lingual heterogeneous clinical texts. Bmc Medical Informatics and Decision Making 18(Suppl 1): 22
Lloyd, J.E.; Song, H.J.; Dennis, S.M.; Dunbar, N.; Harris, E.; Harris, M.F. 2018: A paucity of strategies for developing health literate organisations: a systematic review. Plos one 13(4): E0195018
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Kindy, J.; Roer, D.; Wanovich, R.; McMurray, S. 2018: A payer-provider partnership for integrated care of patients receiving dialysis. American Journal of Managed Care 24(4): 204-208
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Qian, Y.; Zhang, Z.; Tian, W.; Wen, L.; Jiang, L. 2018: A Pb2+ ionic gate with enhanced stability and improved sensitivity based on a 4'-aminobenzo-18-crown-6 modified funnel-shaped nanochannel. Faraday Discussions 210: 101-111
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Li, M.; Yang, X.; Lu, X.; Dai, N.; Zhang, S.; Cheng, Y.; Zhang, L.; Yang, Y.; Liu, Y.; Yang, Z.; Wang, D.; Wilson, D.M. 2018: APE1 deficiency promotes cellular senescence and premature aging features. Nucleic Acids Research 46(11): 5664-5677
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McIlwain, D.W.; Fishel, M.L.; Boos, A.; Kelley, M.R.; Jerde, T.J. 2018: APE1/Ref-1 redox-specific inhibition decreases survivin protein levels and induces cell cycle arrest in prostate cancer cells. Oncotarget 9(13): 10962-10977
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Attanasi, M.; Petrosino, M.I.; Guidone, P.I.; Rapino, D.; Comegna, L.; Rossi, N.; Blasetti, A.; Chiarelli, F. 2018: A pediatric case of rhabdomyolysis with acute renal failure due to co-infection with Epstein-Barr virus and Human herpesvirus 6. Archives of Medical Science: Ams 14(1): 254-256
Li, A.W.; Lalor, L.E.; Bellodi Schmidt, F.; Luu, M. 2018: A pediatric case of squamous cell cancer in situ in the setting of sclerodermatous graft-versus-host disease and voriconazole treatment. Pediatric Dermatology 35(3): E165-E169
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Velema, M.S.; Dekkers, T.; Hermus, A.R.M.M.; Timmers, H.J.L.M.; Langenhuijsen, J.; Arntz, M.; Kusters, B.; Eisenhofer, G.; Lenders, J.W.M.; Deinum, J. 2018: A pedunculated aldosterone-producing adenoma drained by an extra vein causing puzzling results of adrenal vein sampling. Clinical Endocrinology 89(2): 242-244
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Kamali-Sadeghian, M.; Bot, P.T.G.; Tukkie, R.; Wellens, H.J.; van Doorn, D.J. 2018: A peek behind the curtain. Netherlands Heart Journal: Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 26(9): 465-466
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Kumar, R.Vinay.; Bhasker, S. 2018: A peek into epidemiology, screening, management of breast cancer in developing countries: Experience from two regional cancer centers in India. Breast Journal 24(3): 422-423
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Thankappan, K.R.; Sathish, T.; Tapp, R.J.; Shaw, J.E.; Lotfaliany, M.; Wolfe, R.; Absetz, P.; Mathews, E.; Aziz, Z.; Williams, E.D.; Fisher, E.B.; Zimmet, P.Z.; Mahal, A.; Balachandran, S.; D'Esposito, F.; Sajeev, P.; Thomas, E.; Oldenburg, B. 2018: A peer-support lifestyle intervention for preventing type 2 diabetes in India: A cluster-randomized controlled trial of the Kerala Diabetes Prevention Program. Plos Medicine 15(6): E1002575
St Clair Russell, J.; Southerland, S.; Huff, E.D.; Thomson, M.; Meyer, K.B.; Lynch, J.R. 2017: A Peer-to-Peer Mentoring Program for In-Center Hemodialysis: A Patient-Centered Quality Improvement Program. Nephrology Nursing Journal: Journal of the American Nephrology Nurses' Association 44(6): 481-496
Chen, S.-L.; Fu, R.-H.; Liao, S.-F.; Liu, S.-P.; Lin, S.-Z.; Wang, Y.-C. 2018: A PEG-Based Hydrogel for Effective Wound Care Management. Cell Transplantation 27(2): 275-284
Lv, C.-Y.; Ding, W.-J.; Wang, Y.-L.; Zhao, Z.-Y.; Li, J.-H.; Chen, Y.; Lv, J. 2018: A PEG-based method for the isolation of urinary exosomes and its application in renal fibrosis diagnostics using cargo miR-29c and miR-21 analysis. International Urology and Nephrology 50(5): 973-982
Li, C.-A.; Ji, W.; Qu, J.; Jing, S.; Gao, F.; Zhu, D.-R. 2018: A PEG/copper(i) halide cluster as an eco-friendly catalytic system for C-N bond formation. Dalton Transactions 47(22): 7463-7470
Cuccio, V.; Gallese, V. 2018: A Peircean account of concepts: grounding abstraction in phylogeny through a comparative neuroscientific perspective. Philosophical Transactions of the Royal Society of London. Series B Biological Sciences 373(1752)
Liu, D.-R.; Hu, W.; Chen, G.-Z. 2018: Apelin-12 exerts neuroprotective effect against ischemia-reperfusion injury by inhibiting JNK and P38MAPK signaling pathway in mouse. European Review for Medical and Pharmacological Sciences 22(12): 3888-3895
Xu, W.; Gao, L.; Li, T.; Zheng, J.; Shao, A.; Zhang, J. 2018: Apelin-13 Alleviates Early Brain Injury after Subarachnoid Hemorrhage via Suppression of Endoplasmic Reticulum Stress-mediated Apoptosis and Blood-Brain Barrier Disruption: Possible Involvement of ATF6/CHOP Pathway. Neuroscience 388: 284-296
Haghparast, E.; Esmaeili-Mahani, S.; Abbasnejad, M.; Sheibani, V. 2018: Apelin-13 ameliorates cognitive impairments in 6-hydroxydopamine-induced substantia nigra lesion in rats. Neuropeptides 68: 28-35
O'Harte, F.P.M.; Parthsarathy, V.; Hogg, C.; Flatt, P.R. 2018: Apelin-13 analogues show potent in vitro and in vivo insulinotropic and glucose lowering actions. Peptides 100: 219-228
Chen, T.; Liu, N.; Xu, G.-M.; Liu, T.-J.; Liu, Y.; Zhou, Y.; Huo, S.-B.; Zhang, K. 2017: Apelin13/APJ promotes proliferation of colon carcinoma by activating Notch3 signaling pathway. Oncotarget 8(60): 101697-101706
Alpua, M.; Turkel, Y.; Dag, E.; Kisa, U. 2018: Apelin-13: a Promising Biomarker for Multiple Sclerosis?. Annals of Indian Academy of Neurology 21(2): 126-129
Jiang, Y.; Liu, H.; Ji, B.; Wang, Z.; Wang, C.; Yang, C.; Pan, Y.; Chen, J.; Cheng, B.; Bai, B. 2018: Apelin‑13 attenuates ER stress‑associated apoptosis induced by MPP+ in SH‑SY5Y cells. International Journal of Molecular Medicine 42(3): 1732-1740
Wu, F.; Qiu, J.; Fan, Y.; Zhang, Q.; Cheng, B.; Wu, Y.; Bai, B. 2018: Apelin-13 attenuates ER stress-mediated neuronal apoptosis by activating Gαi/Gαq-CK2 signaling in ischemic stroke. Experimental Neurology 302: 136-144
Han, X.-F.; Zhang, X.-X.; Liu, K.-M.; Zhang, Q. 2018: Apelin-13 deficiency alters cortical bone geometry, organic bone matrix, and inhibits Wnt/β-catenin signaling. General and Comparative Endocrinology 267: 29-35
Saral, S.; Alkanat, M.; Sumer, A.; Canpolat, S. 2018: Apelin-13 increased food intake with serum ghrelin and leptin levels in male rats. Bratislavske Lekarske Listy 119(1): 47-53
Li, Y.; Bai, Y.-J.; Jiang, Y.-R.; Yu, W.-Z.; Shi, X.; Chen, L.; Feng, J.; Sun, G.-B. 2018: Apelin-13 Is an Early Promoter of Cytoskeleton and Tight Junction in Diabetic Macular Edema via PI-3K/Akt and MAPK/Erk Signaling Pathways. Biomed Research International 2018: 3242574
Tian, S.-W.; Xu, F.; Gui, S.-J. 2018: Apelin-13 reverses memory impairment and depression-like behavior in chronic social defeat stressed rats. Peptides 108: 1-6
Fraga-Silva, R.A.; Seeman, H.; Montecucco, F.; da Silva, A.R.; Burger, F.; Costa-Fraga, F.P.; Anguenot, L.éa.; Mach, F.ço.; Dos Santos, R.A.S.; Stergiopulos, N.; da Silva, R.F. 2018: Apelin-13 treatment enhances the stability of atherosclerotic plaques. European Journal of Clinical Investigation 48(3)
Li, X.; Yu, L.; Gao, J.; Bi, X.; Zhang, J.; Xu, S.; Wang, M.; Chen, M.; Qiu, F.; Fu, G. 2018: Apelin Ameliorates High Glucose-Induced Downregulation of Connexin 43 via AMPK-Dependent Pathway in Neonatal Rat Cardiomyocytes. Aging and Disease 9(1): 66-76
Różycka, M.; Kurowska, P.; Grzesiak, M.łg.; Kotula-Balak, M.łg.; Tworzydło, W.ła.; Rame, C.; Gregoraszczuk, E.; Dupont, J.; Rak, A. 2018: Apelin and apelin receptor at different stages of corpus luteum development and effect of apelin on progesterone secretion and 3β-hydroxysteroid dehydrogenase (3β-HSD) in pigs. Animal Reproduction Science 192: 251-260
Parikh, V.N.; Liu, J.; Shang, C.; Woods, C.; Chang, A.C.; Zhao, M.; Charo, D.N.; Grunwald, Z.; Huang, Y.; Seo, K.; Tsao, P.S.; Bernstein, D.; Ruiz-Lozano, P.; Quertermous, T.; Ashley, E.A. 2018: Apelin and APJ orchestrate complex tissue-specific control of cardiomyocyte hypertrophy and contractility in the hypertrophy-heart failure transition. American Journal of Physiology. Heart and Circulatory Physiology 315(2): H348-H356
Salska, A.; Dziuba, M.ł; Salski, W.; Chizynski, K.; Zielinska, M. 2018: Apelin and Atrial Fibrillation: the Role in the Arrhythmia Recurrence Prognosis. Disease Markers 2018: 5285392
Kuba, K.; Sato, T.; Imai, Y.; Yamaguchi, T. 2019: Apelin and Elabela/Toddler; double ligands for APJ/Apelin receptor in heart development, physiology, and pathology. Peptides 111: 62-70
Yang, R.; Fang, W.; Liang, J.; Lin, C.; Wu, S.; Yan, S.; Hu, C.; Ke, X. 2018: Apelin/APJ axis improves angiotensin II-induced endothelial cell senescence through AMPK/SIRT1 signaling pathway. Archives of Medical Science: Ams 14(4): 725-734
Sekerci, R.; Acar, N.; Tepekoy, F.; Ustunel, I.; Keles-Celik, N. 2018: Apelin/APJ expression in the heart and kidneys of hypertensive rats. Acta Histochemica 120(3): 196-204
Luo, X.; Liu, J.; Zhou, H.; Chen, L. 2018: Apelin/APJ system: a critical regulator of vascular smooth muscle cell. Journal of Cellular Physiology 233(7): 5180-5188
Lv, S.-Y.; Cui, B.; Chen, W.-D.; Wang, Y.-D. 2017: Apelin/APJ system: a key therapeutic target for liver disease. Oncotarget 8(67): 112145-112151
Masoumi, J.; Abbasloui, M.; Parvan, R.; Mohammadnejad, D.; Pavon-Djavid, G.; Barzegari, A.; Abdolalizadeh, J. 2018: Apelin, a promising target for Alzheimer disease prevention and treatment. Neuropeptides 70: 76-86
Wang, C.; Liu, X.; Kong, D.; Qin, X.; Li, Y.; Teng, X.; Huang, X. 2017: Apelin as a novel drug for treating preeclampsia. Experimental and Therapeutic Medicine 14(6): 5917-5923
Chen, R.; Jiang, P.; Liu, L.-Y.; Gao, Y.; Yang, X.-X.; Cai, Z.-C.; Fan, X.-F.; Gong, Y.-S.; Mao, S.-Z. 2017: Apelin attenuates hypoxia induced pulmonary hypertension of mice through regulation of lipid metabolism. Zhongguo Ying Yong Sheng Li Xue Za Zhi 33(6): 493-496
Podgórska, M.; Pietraszek-Gremplewicz, K.; Nowak, D. 2018: Apelin Effects Migration and Invasion Abilities of Colon Cancer Cells. Cells 7(8)
Shin, K.; Kenward, C.; Rainey, J.K. 2017: Apelinergic System Structure and Function. Comprehensive Physiology 8(1): 407-450
Kurowska, P.; Barbe, A.; Różycka, M.; Chmielińska, J.; Dupont, J.; Rak, A. 2018: Apelin in Reproductive Physiology and Pathology of Different Species: a Critical Review. International Journal of Endocrinology 2018: 9170480
Zhang, H.-H.; Wang, Y.-J.; Zheng, C.; Wang, M.-Y.; Zhu, D.-N. 2018: Apelin in the hypothalamic paraventricular nucleus improves cardiac function in surgical trauma rats. Sheng Li Xue Bao: 70(2): 99-105
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Mekoba, B.C.; Turingan, E.M.; Roberts, P.A.; Mason, S.; Willoughby, I.; Taylor, C.; Stivers, A.; Valgus, J. 2018: A pharmacy-led United States Pharmacopeia ( USP ) chapter 800 compliance collaborative at an academic medical center. American Journal of Health-System Pharmacy: Ajhp: Official Journal of the American Society of Health-System Pharmacists 75(10): 627-632
DellaVecchia, M.J.; Claudio, A.M.; Fairclough, J.L. 2017: A pharmacy student's role as a teaching assistant in an undergraduate medicinal chemistry course - Implementation, evaluation, and unexpected opportunities for educational outreach. Currents in Pharmacy Teaching and Learning 9(6): 1080-1090
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Manley, P.E.; Trippett, T.; Smith, A.A.; Macy, M.E.; Leary, S.E.S.; Boklan, J.; Cohen, K.J.; Goldman, S.; Kilburn, L.B.; Dhall, G.; Devin, J.; Herzog, C.E.; Partap, S.; Fauchet, F.; Badreddine, E.; Bernard, J.P.; Chi, S.N. 2018: A phase 1/2 dose-finding, safety, and activity study of cabazitaxel in pediatric patients with refractory solid tumors including tumors of the central nervous system. Pediatric Blood and Cancer 65(9): E27217
Soliman, H.; Khambati, F.; Han, H.S.; Ismail-Khan, R.; Bui, M.M.; Sullivan, D.M.; Antonia, S. 2018: A phase-1/2 study of adenovirus-p53 transduced dendritic cell vaccine in combination with indoximod in metastatic solid tumors and invasive breast cancer. Oncotarget 9(11): 10110-10117
Ikeda, M.; Morimoto, M.; Tajimi, M.; Inoue, K.; Benhadji, K.A.; Lahn, M.M.F.; Sakai, D. 2019: A phase 1b study of transforming growth factor-beta receptor i inhibitor galunisertib in combination with sorafenib in Japanese patients with unresectable hepatocellular carcinoma. Investigational new Drugs 37(1): 118-126
Matei, D.; Ghamande, S.; Roman, L.; Alvarez Secord, A.; Nemunaitis, J.; Markham, M.J.; Nephew, K.P.; Jueliger, S.; Oganesian, A.; Naim, S.; Su, X.Y.; Keer, H.; Azab, M.; Fleming, G.F. 2018: A Phase i Clinical Trial of Guadecitabine and Carboplatin in Platinum-Resistant, Recurrent Ovarian Cancer: Clinical, Pharmacokinetic, and Pharmacodynamic Analyses. Clinical Cancer Research: An Official Journal of the American Association for Cancer Research 24(10): 2285-2293
Ferrarotto, R.; Eckhardt, G.; Patnaik, A.; LoRusso, P.; Faoro, L.; Heymach, J.V.; Kapoun, A.M.; Xu, L.; Munster, P. 2018: A phase i dose-escalation and dose-expansion study of brontictuzumab in subjects with selected solid tumors. Annals of Oncology: Official Journal of the European Society for Medical Oncology 29(7): 1561-1568
King, G.T.; Eaton, K.D.; Beagle, B.R.; Zopf, C.J.; Wong, G.Y.; Krupka, H.I.; Hua, S.Y.; Messersmith, W.A.; El-Khoueiry, A.B. 2018: A phase 1, dose-escalation study of PF-06664178, an anti-Trop-2/Aur0101 antibody-drug conjugate in patients with advanced or metastatic solid tumors. Investigational new Drugs 36(5): 836-847
Greil, R.; Greil-Ressler, S.; Weiss, L.; Schönlieb, C.; Magnes, T.; Radl, B.; Bolger, G.T.; Vcelar, B.; Sordillo, P.P. 2018: A phase 1 dose-escalation study on the safety, tolerability and activity of liposomal curcumin (Lipocurc™) in patients with locally advanced or metastatic cancer. Cancer ChemoTherapy and Pharmacology 82(4): 695-706
Majumdar, S.; Tirona, R.; Mashegu, H.; Desai, J.; Shannon, N.T.; Summar, M.; Cunningham, G.; Darbari, D.; Nickel, R.; Campbell, A.; Barr, F.E. 2019: A phase 1 dose-finding study of intravenous L-citrulline in sickle cell disease: a potential novel therapy for sickle cell pain crisis. British Journal of Haematology 184(4): 634-636
Leong, F.J.; Jain, J.P.; Feng, Y.; Goswami, B.; Stein, D.S. 2018: A phase 1 evaluation of the pharmacokinetic/pharmacodynamic interaction of the anti-malarial agents KAF156 and piperaquine. Malaria Journal 17(1): 7
Carducci, M.; Shaheen, M.; Markman, B.; Hurvitz, S.; Mahadevan, D.; Kotasek, D.; Goodman, O.B.; Rasmussen, E.; Chow, V.; Juan, G.; Friberg, G.R.; Gamelin, E.; Vogl, F.D.; Desai, J. 2018: A phase 1, first-in-human study of AMG 900, an orally administered pan-Aurora kinase inhibitor, in adult patients with advanced solid tumors. Investigational new Drugs 36(6): 1060-1071
Wells, J.A.; Gonzales, C.R.; Berger, B.B.; Gonzalez, V.H.; Sippy, B.D.; Burian, G. 2018: A Phase 1, Open-Label, Dose-Escalation Trial to Investigate Safety and Tolerability of Single Intravitreous Injections of ICON-1 Targeting Tissue Factor in Wet AMD. Ophthalmic Surgery Lasers and Imaging Retina 49(5): 336-345
Dean, E.; Banerji, U.; Schellens, J.H.M.; Krebs, M.G.; Jimenez, B.; van Brummelen, E.; Bailey, C.; Casson, E.; Cripps, D.; Cullberg, M.; Evans, S.; Foxley, A.; Lindemann, J.; Rugman, P.; Taylor, N.; Turner, G.; Yates, J.; Lawrence, P. 2018: A Phase 1, open-label, multicentre study to compare the capsule and tablet formulations of AZD5363 and explore the effect of food on the pharmacokinetic exposure, safety and tolerability of AZD5363 in patients with advanced solid malignancies: OAK. Cancer ChemoTherapy and Pharmacology 81(5): 873-883
Barbee, L.A.; Nayak, S.U.; Blumer, J.L.; OʼRiordan, M.Ann.; Gray, W.; Zenilman, J.M.; Golden, M.R.; Griffiss, J.McLeod. 2018: A Phase 1 Pharmacokinetic and Safety Study of Extended-Duration, High-dose Cefixime for Cephalosporin-resistant Neisseria gonorrhoeae in the Pharynx. Sexually Transmitted Diseases 45(10): 677-683
Armas, D.; Holt, R.J.; Confer, N.F.; Checani, G.C.; Obaidi, M.; Xie, Y.; Brannagan, M. 2018: A Phase 1 Pharmacokinetic Study of Cysteamine Bitartrate Delayed-Release Capsules Following Oral Administration with Orange Juice, Water, or Omeprazole in Cystinosis. Advances in Therapy 35(2): 199-209
Sahasrabudhe, V.; Saur, D.; Matschke, K.; Terra, S.G.; Hickman, A.; Huyghe, I.; Shi, H.; Cutler, D.L. 2018: A Phase 1, Randomized, Placebo- and Active-Controlled Crossover Study to Determine the Effect of Single-Dose Ertugliflozin on QTc Interval in Healthy Volunteers. Clinical Pharmacology in Drug Development 7(5): 513-523
Vandell, A.G.; Inoue, S.; Dennie, J.; Nagasawa, Y.; Gajee, R.; Pav, J.; Zhang, G.; Zamora, C.; Masuda, N.; Senaldi, G. 2018: Phase 1 Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Oral Doses of DS-2969b, a Novel GyrB Inhibitor, in Healthy Subjects. Antimicrobial Agents and ChemoTherapy 62(5)
Harding, J.J.; Do, R.K.; Dika, I.E.; Hollywood, E.; Uhlitskykh, K.; Valentino, E.; Wan, P.; Hamilton, C.; Feng, X.; Johnston, A.; Bomalaski, J.; Li, C.-F.; O'Reilly, E.M.; Abou-Alfa, G.K. 2018: A phase 1 study of ADI-PEG 20 and modified FOLFOX6 in patients with advanced hepatocellular carcinoma and other gastrointestinal malignancies. Cancer ChemoTherapy and Pharmacology 82(3): 429-440
Marasco, S.F.; Tutungi, E.; Vallance, S.A.; Udy, A.A.; Negri, J.C.; Zimmet, A.D.; McGiffin, D.C.; Pellegrino, V.A.; Moshinsky, R.A. 2018: A Phase 1 Study of a Novel Bidirectional Perfusion Cannula in Patients Undergoing Femoral Cannulation for Cardiac Surgery. Innovations 13(2): 97-103
Heiblig, M.ël.; Elhamri, M.; Thomas, X.; Plesa, A.; Raffoux, E.; Hayette, S. 2018: A phase 1 study of chemosensitization with plerixafor plus G-CSF in adults with relapsed acute myeloid leukemia. Leukemia Research 72: 7-11
Redner, R.L.; Beumer, J.H.; Kropf, P.; Agha, M.; Boyiadzis, M.; Dorritie, K.; Farah, R.; Hou, J-Zhao.; Im, A.; Lim, S.H.; Raptis, A.; Sehgal, A.; Christner, S.M.; Normolle, D.; Johnson, D.E. 2018: A phase-1 study of dasatinib plus all-trans retinoic acid in acute myeloid leukemia. Leukemia and Lymphoma 59(11): 2595-2601
Schafer, E.S.; Rau, R.E.; Berg, S.; Liu, X.; Minard, C.G.; D'Adamo, D.; Scott, R.; Reyderman, L.; Martinez, G.; Devarajan, S.; Reid, J.M.; Fox, E.; Weigel, B.J.; Blaney, S.M. 2018: A phase 1 study of eribulin mesylate (E7389), a novel microtubule-targeting chemotherapeutic agent, in children with refractory or recurrent solid tumors: a Children's Oncology Group Phase 1 Consortium study (ADVL1314). Pediatric Blood and Cancer 65(8): E27066
Ujjani, C.; Wang, H.; Skarbnik, A.; Trivedi, N.; Ramzi, P.; Khan, N.; Cheson, B.D. 2018: A phase 1 study of lenalidomide and ibrutinib in combination with rituximab in relapsed and refractory CLL. Blood Advances 2(7): 762-768
Vey, N.; Karlin, L.; Sadot-Lebouvier, S.; Broussais, F.; Berton-Rigaud, D.; Rey, J.ér.ôm.; Charbonnier, A.; Marie, D.; André, P.; Paturel, C.; Zerbib, R.; Bennouna, J.; Salles, G.; Gonçalves, A. 2018: A phase 1 study of lirilumab (antibody against killer immunoglobulin-like receptor antibody KIR2D; IPH2102) in patients with solid tumors and hematologic malignancies. Oncotarget 9(25): 17675-17688
Ali, S.O.; Yu, X.Q.; Robbie, G.J.; Wu, Y.; Shoemaker, K.; Yu, L.; DiGiandomenico, A.; Keller, A.E.; Anude, C.; Hernandez-Illas, M.; Bellamy, T.; Falloon, J.; Dubovsky, F.; Jafri, H.S. 2019: Phase 1 study of MEDI3902, an investigational anti-Pseudomonas aeruginosa PcrV and Psl bispecific human monoclonal antibody, in healthy adults. Clinical Microbiology and Infection: the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 25(5): 629.E1-629.E6
Van der Biessen, D.A.J.; Gietema, J.A.; de Jonge, M.J.A.; Desar, I.M.E.; den Hollander, M.W.; Dudley, M.; Dunbar, M.; Hetman, R.; Serpenti, C.; Xiong, H.; Mittapalli, R.K.; Timms, K.M.; Ansell, P.; Ratajczak, C.K.; Shepherd, S.P.; van Herpen, C.M.L. 2018: A phase 1 study of PARP-inhibitor ABT-767 in advanced solid tumors with BRCA1/2 mutations and high-grade serous ovarian, fallopian tube, or primary peritoneal cancer. Investigational new Drugs 36(5): 828-835
Jackson, L.A.; Rupp, R.; Papadimitriou, A.; Wallace, D.; Raanan, M.; Moss, K.J. 2018: A phase 1 study of safety and immunogenicity following intradermal administration of a tetravalent dengue vaccine candidate. Vaccine 36(27): 3976-3983
Cohen-Barak, O.; Weiss, S.; Rasamoelisolo, M.; Faulhaber, N.; Yeung, P.P.; Loupe, P.S.; Yoon, E.; Gandhi, M.D.; Spiegelstein, O.; Aycardi, E. 2018: A phase 1 study to assess the pharmacokinetics, safety, and tolerability of fremanezumab doses (225 mg, 675 mg and 900 mg) in Japanese and Caucasian healthy subjects. Cephalalgia: An International Journal of Headache 38(13): 1960-1971
Lues, I.; Weber, F.; Meyer, A.; Bühring, U.; Hoffmann, T.; Kühn-Wache, K.; Manhart, S.; Heiser, U.; Pokorny, R.; Chiesa, J.; Glund, K. 2015: A phase 1 study to evaluate the safety and pharmacokinetics of PQ912, a glutaminyl cyclase inhibitor, in healthy subjects. Alzheimer's and Dementia 1(3): 182-195
Aslostovar, L.; Boyd, A.L.; Almakadi, M.; Collins, T.J.; Leong, D.P.; Tirona, R.G.; Kim, R.B.; Julian, J.A.; Xenocostas, A.; Leber, B.; Levine, M.N.; Foley, R.; Bhatia, M. 2018: A phase 1 trial evaluating thioridazine in combination with cytarabine in patients with acute myeloid leukemia. Blood Advances 2(15): 1935-1945
Schmitz-Winnenthal, F.H.; Hohmann, N.; Schmidt, T.; Podola, L.; Friedrich, T.; Lubenau, H.; Springer, M.; Wieckowski, Sébastien.; Breiner, K.M.; Mikus, G.; Büchler, M.W.; Keller, A-Valerie.; Koc, R.; Springfeld, C.; Knebel, P.; Bucur, M.; Grenacher, L.; Haefeli, W.E.; Beckhove, P. 2018: A phase 1 trial extension to assess immunologic efficacy and safety of prime-boost vaccination with VXM01, an oral T cell vaccine against VEGFR2, in patients with advanced pancreatic cancer. Oncoimmunology 7(4): E1303584
Green, D.S.; Nunes, A.T.; David-Ocampo, V.; Ekwede, I.B.; Houston, N.D.; Highfill, S.L.; Khuu, H.; Stroncek, D.F.; Steinberg, S.M.; Zoon, K.C.; Annunziata, C.M. 2018: A Phase 1 trial of autologous monocytes stimulated ex vivo with Sylatron® (Peginterferon alfa-2b) and Actimmune® (Interferon gamma-1b) for intra-peritoneal administration in recurrent ovarian cancer. Journal of Translational Medicine 16(1): 196
Fehniger, T.A.; Miller, J.S.; Stuart, R.K.; Cooley, S.; Salhotra, A.; Curtsinger, J.; Westervelt, P.; DiPersio, J.F.; Hillman, T.M.; Silver, N.; Szarek, M.; Gorelik, L.; Lowdell, M.W.; Rowinsky, E. 2018: A Phase 1 Trial of CNDO-109-Activated Natural Killer Cells in Patients with High-Risk Acute Myeloid Leukemia. Biology of Blood and Marrow Transplantation: Journal of the American Society for Blood and Marrow Transplantation 24(8): 1581-1589
Phillips, T.; Barr, P.M.; Park, S.I.; Kolibaba, K.; Caimi, P.F.; Chhabra, S.; Kingsley, E.C.; Boyd, T.; Chen, R.; Carret, A.-S.; Gartner, E.M.; Li, H.; Yu, C.; Smith, D.C. 2019: A phase 1 trial of SGN-CD70A in patients with CD70-positive diffuse large B cell lymphoma and mantle cell lymphoma. Investigational new Drugs 37(2): 297-306
Stein, E.M.; Walter, R.B.; Erba, H.P.; Fathi, A.T.; Advani, A.S.; Lancet, J.E.; Ravandi, F.; Kovacsovics, T.; DeAngelo, D.J.; Bixby, D.; Faderl, S.; Jillella, A.P.; Ho, P.A.; O'Meara, M.M.; Zhao, B.; Biddle-Snead, C.; Stein, A.S. 2018: A phase 1 trial of vadastuximab talirine as monotherapy in patients with CD33-positive acute myeloid leukemia. Blood 131(4): 387-396
Fathi, A.T.; Erba, H.P.; Lancet, J.E.; Stein, E.M.; Ravandi, F.; Faderl, S.; Walter, R.B.; Advani, A.S.; DeAngelo, D.J.; Kovacsovics, T.J.; Jillella, A.; Bixby, D.; Levy, M.Y.; O'Meara, M.M.; Ho, P.A.; Voellinger, J.; Stein, A.S. 2018: A phase 1 trial of vadastuximab talirine combined with hypomethylating agents in patients with CD33-positive AML. Blood 132(11): 1125-1133
Kindy, M.; Lupinacci, P.; Chau, R.; Shum, T.; Ko, D. 2017: A Phase 2A randomized, double-blind, placebo-controlled pilot trial of GM604 in patients with Amyotrophic Lateral Sclerosis (ALS Protocol GALS-001) and a single compassionate patient treatment (Protocol GALS-C). F1000research 6: 230
Obiero, C.W.; Ndiaye, A.G.W.; Sciré, A.S.; Kaunyangi, B.M.; Marchetti, E.; Gone, A.M.; Schütte, L.D.; Riccucci, D.; Auerbach, J.; Saul, A.; Martin, L.B.; Bejon, P.; Njuguna, P.; Podda, A. 2017: A Phase 2a Randomized Study to Evaluate the Safety and Immunogenicity of the 1790GAHB Generalized Modules for Membrane Antigen Vaccine against Shigella sonnei Administered Intramuscularly to Adults from a Shigellosis-Endemic Country. Frontiers in Immunology 8: 1884
Kollmeier, A.P.; Barnathan, E.S.; O'Brien, C.; Chen, B.; Xia, Y.K.; Zhou, B.; Loza, M.J.; Silkoff, P.E.; Ge, M.; Thurmond, R.L. 2018: A phase 2a study of toreforant, a histamine H4 receptor antagonist, in eosinophilic asthma. Annals of Allergy Asthma and Immunology: Official Publication of the American College of Allergy Asthma and Immunology 121(5): 568-574
Fullerton, T.; Binneman, B.; David, W.; Delnomdedieu, M.; Kupiec, J.; Lockwood, P.; Mancuso, J.; Miceli, J.; Bell, J. 2018: A Phase 2 clinical trial of PF-05212377 (SAM-760) in subjects with mild to moderate Alzheimer's disease with existing neuropsychiatric symptoms on a stable daily dose of donepezil. Alzheimer's Research and Therapy 10(1): 38
Elewski, B.E.; Kircik, L.H.; Stasko, N.; De Leon, E.; Enloe, C.; Durham, T.; Maeda-Chubachi, T. 2018: A Phase 2, Controlled, Dose-Ranging Study of SB208, an Investigational Topical Nitric Oxide-Releasing Drug, for the Treatment of Tinea Pedis. Journal of Drugs in Dermatology: Jdd 17(8): 888-893
Vincenti, F.; Fervenza, F.C.; Campbell, K.N.; Diaz, M.; Gesualdo, L.; Nelson, P.; Praga, M.; Radhakrishnan, J.; Sellin, L.; Singh, A.; Thornley-Brown, D.; Veronese, F.V.ís.; Accomando, B.; Engstrand, S.; Ledbetter, S.; Lin, J.; Neylan, J.; Tumlin, J. 2017: A Phase 2, Double-Blind, Placebo-Controlled, Randomized Study of Fresolimumab in Patients with Steroid-Resistant Primary Focal Segmental Glomerulosclerosis. Kidney International Reports 2(5): 800-810
Trnĕný, M.; Verhoef, G.; Dyer, M.J.; Ben Yehuda, D.; Patti, C.; Canales, M.; Lopez, A.és.; Awan, F.T.; Montgomery, P.G.; Janikova, A.; Barbui, A.M.; Sulek, K.; Terol, M.J.; Radford, J.; Guidetti, A.; Di Nicola, M.; Siraudin, L.; Hatteville, L.; Schwab, S.; Oprea, C.; Gianni, A.M. 2018: A phase Ii multicenter study of the anti-CD19 antibody drug conjugate coltuximab ravtansine (SAR3419) in patients with relapsed or refractory diffuse large B-cell lymphoma previously treated with rituximab-based immunotherapy. Haematologica 103(8): 1351-1358
Gault, L.M.; Ritchie, C.W.; Robieson, W.Z.; Pritchett, Y.; Othman, A.A.; Lenz, R.A. 2015: A phase 2 randomized, controlled trial of the α7 agonist ABT-126 in mild-to-moderate Alzheimer's dementia. Alzheimer's and Dementia 1(1): 81-90
Brand, S.R.; Degenhardt, T.P.; Person, K.; Sobel, J.D.; Nyirjesy, P.; Schotzinger, R.J.; Tavakkol, A. 2018: A phase 2, randomized, double-blind, placebo-controlled, dose-ranging study to evaluate the efficacy and safety of orally administered VT-1161 in the treatment of recurrent vulvovaginal candidiasis. American Journal of Obstetrics and Gynecology 218(6): 624.E1-624.E9
Schreiber, S.; Siegel, C.A.; Friedenberg, K.A.; Younes, Z.H.; Seidler, U.; Bhandari, B.R.; Wang, K.; Wendt, E.; McKevitt, M.; Zhao, S.; Sundy, J.S.; Lee, S.D.; Loftus, E.V. 2018: A Phase 2, Randomized, Placebo-Controlled Study Evaluating Matrix Metalloproteinase-9 Inhibitor, Andecaliximab, in Patients with Moderately to Severely Active Crohn's Disease. Journal of Crohn's and Colitis 12(9): 1014-1020
Katz, J.E.; Molina, M.L.; Clavijo, R.; Prakash, N.Soodana.; Ramasamy, R. 2018: A Phase 2 Randomized Trial To Evaluate Different Dose Regimens of Low-intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction: Clinical Trial Update. European Urology Focus 4(3): 336-337
Yadav, B.S.; Sharma, S.C. 2018: A Phase 2 Study of 2 Weeks of Adjuvant Whole Breast/Chest Wall and/or Regional Nodal Radiation Therapy for Patients with Breast Cancer. International Journal of Radiation Oncology Biology Physics 100(4): 874-881
Nakano, T.; Sumino, S.; Takanami, Y.; Mitsuya, N.; Nakatome, K. 2018: A phase 2 study of a combined diphtheria-tetanus-acellular pertussis vaccine with a Sabin-derived inactivated poliovirus vaccine in children. Human Vaccines and Immunotherapeutics 14(12): 2940-2949
Kumagai, H.; Kusaba, H.; Yamanaka, T.; Nio, K.; Inadomi, K.; Takayoshi, K.; Ito, M.; Tamura, S.; Makiyama, A.; Makiyama, C.; Hirano, G.; Shibata, Y.; Shirakawa, T.; Mitsugi, K.; Ariyama, H.; Esaki, T.; Akashi, K.; Baba, E. 2018: A phase 2 study of fosaprepitant combined with high-dose dexamethasone for Japanese cancer patients receiving highly emetogenic chemotherapy. Medicine 97(25): E11042
O'Donnell, E.K.; Laubach, J.P.; Yee, A.J.; Chen, T.; Huff, C.A.; Basile, F.G.; Wade, P.M.; Paba-Prada, C.E.; Ghobrial, I.M.; Schlossman, R.L.; Burke, J.N.; Harrington, C.C.; Lively, K.J.; Lyons, H.F.; Munshi, N.C.; Anderson, K.C.; Trippa, L.; Richardson, P.G.; Raje, N.S. 2018: A phase 2 study of modified lenalidomide, bortezomib and dexamethasone in transplant-ineligible multiple myeloma. British Journal of Haematology 182(2): 222-230
Chen, C.I.; Paul, H.; Le, L.W.; Wei, E.N.; Snitzler, S.; Wang, T.; Levina, O.; Kakar, S.; Lau, A.; Queau, M.; Johnston, J.B.; Smith, D.A.; Trudel, S. 2019: A phase 2 study of ofatumumab (Arzerra ® ) in combination with a pan-AKT inhibitor (afuresertib) in previously treated patients with chronic lymphocytic leukemia (CLL). Leukemia and Lymphoma 60(1): 92-100
Barata, P.; Cooney, M.; Tyler, A.; Wright, J.; Dreicer, R.; Garcia, J.A. 2018: A phase 2 study of OSI-906 (linsitinib, an insulin-like growth factor receptor-1 inhibitor) in patients with asymptomatic or mildly symptomatic (non-opioid requiring) metastatic castrate resistant prostate cancer (CRPC). Investigational new Drugs 36(3): 451-457
Chari, A.; Cho, H.J.; Dhadwal, A.; Morgan, G.; La, L.; Zarychta, K.; Catamero, D.; Florendo, E.; Stevens, N.; Verina, D.; Chan, E.; Leshchenko, V.; Laganà, A.; Perumal, D.; Mei, A.H.-C.; Tung, K.; Fukui, J.; Jagannath, S.; Parekh, S. 2017: A phase 2 study of panobinostat with lenalidomide and weekly dexamethasone in myeloma. Blood Advances 1(19): 1575-1583
Sonbol, M.Bassam.; Hilal, T.; Dueck, A.C.; Rosenthal, A.C.; Conley, C.R.; Kosiorek, H.E.; Ginos, B.F.; Gano, K.M.; Nichols, C.S.; Leis, J.F.; Johnston, P.B.; Habermann, T.M.; Northfelt, D.W.; Bergsagel, P.Leif.; Inwards, D.J.; Witzig, T.E.; Ansell, S.M.; Reeder, C.B. 2018: A phase 2 study of rituximab, cyclophosphamide, bortezomib and dexamethasone (R-CyBorD) in relapsed low grade and mantle cell lymphoma. Leukemia and Lymphoma 59(9): 2128-2134
Pishvaian, M.J.; Slack, R.S.; Jiang, W.; He, A.R.; Hwang, J.J.; Hankin, A.; Dorsch-Vogel, K.; Kukadiya, D.; Weiner, L.M.; Marshall, J.L.; Brody, J.R. 2018: A phase 2 study of the PARP inhibitor veliparib plus temozolomide in patients with heavily pretreated metastatic colorectal cancer. Cancer 124(11): 2337-2346
Ramanathan, R.K.; Weiss, G.J.; Posner, R.G.; Rajeshkumar, N.V.; Jameson, G.; Aziz, M.; Hoering, A.; Bolejack, V.; Maitra, A.; Fulk, M.; Stites, E.C.; Hlavacek, W.S.; Gatalica, Z.; Xiu, J.; Hidalgo, M.; Von Hoff, D.D.; Barrett, M.T. 2017: A phase 2 trial of personalized cytotoxic therapy based on tumor immunohistochemistry in previously treated metastatic pancreatic cancer patients. Journal of Gastrointestinal Oncology 8(6): 925-935
Kanakura, Y.; Shirasugi, Y.; Yamaguchi, H.; Koike, M.; Chou, T.; Okamoto, S.; Achenbach, H.; Wu, J.; Nakaseko, C. 2018: A phase 3b, multicenter, open-label extension study of the long-term safety of anagrelide in Japanese adults with essential thrombocythemia. International Journal of Hematology 108(5): 491-498
Holland, T.L.; O'Riordan, W.; McManus, A.; Shin, E.; Borghei, A.; File, T.M.; Wilcox, M.H.; Torres, A.; Dryden, M.; Lodise, T.; Oguri, T.; Corey, G.R.; McLeroth, P.; Shukla, R.; Huang, D.B. 2018: A Phase 3, Randomized, Double-Blind, Multicenter Study to Evaluate the Safety and Efficacy of Intravenous Iclaprim versus Vancomycin for Treatment of Acute Bacterial Skin and Skin Structure Infections Suspected or Confirmed to be Due to Gram-Positive Pathogens (REVIVE-2 Study). Antimicrobial Agents and ChemoTherapy 62(5)
Ye, D.; Huang, Y.; Zhou, F.; Xie, K.; Matveev, V.; Li, C.; Alexeev, B.; Tian, Y.; Qiu, M.; Li, H.; Zhou, T.; De Porre, P.; Yu, M.; Naini, V.; Liang, H.; Wu, Z.; Sun, Y. 2017: A phase 3, double-blind, randomized placebo-controlled efficacy and safety study of abiraterone acetate in chemotherapy-naïve patients with mCRPC in China, Malaysia, Thailand and Russia. Asian Journal of Urology 4(2): 75-85
Durgam, S.; Chen, C.; Migliore, R.; Prakash, C.; Edwards, J.; Findling, R.L. 2018: A Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of Vilazodone in Adolescents with Major Depressive Disorder. Paediatric Drugs 20(4): 353-363
Deeb, L.C.; Dulude, H.él.èn.; Guzman, C.B.; Zhang, S.; Reiner, B.J.; Piché, C.A.; Pradhan, S.; Zhang, X.M. 2018: A phase 3 multicenter, open-label, prospective study designed to evaluate the effectiveness and ease of use of nasal glucagon in the treatment of moderate and severe hypoglycemia in children and adolescents with type 1 diabetes in the home or school setting. Pediatric Diabetes 19(5): 1007-1013
Chavoustie, S.E.; Gersten, J.K.; Samuel, M.J.; Schwebke, J.R. 2018: A Phase 3, Multicenter, Prospective, Open-Label Study to Evaluate the Safety of a Single Dose of Secnidazole 2 g for the Treatment of Women and Postmenarchal Adolescent Girls with Bacterial Vaginosis. Journal of Women's Health 27(4): 492-497
Huang, D.B.; O'Riordan, W.; Overcash, J.S.; Heller, B.; Amin, F.; File, T.M.; Wilcox, M.H.; Torres, A.; Dryden, M.; Holland, T.L.; McLeroth, P.; Shukla, R.; Corey, G.R. 2018: A Phase 3, Randomized, Double-Blind, Multicenter Study to Evaluate the Safety and Efficacy of Intravenous Iclaprim Vs Vancomycin for the Treatment of Acute Bacterial Skin and Skin Structure Infections Suspected or Confirmed to be Due to Gram-Positive Pathogens: REVIVE-1. Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 66(8): 1222-1229
Lewiecki, E.M.; Blicharski, T.; Goemaere, S.; Lippuner, K.; Meisner, P.D.; Miller, P.D.; Miyauchi, A.; Maddox, J.; Chen, L.; Horlait, S. 2018: A Phase IIi Randomized Placebo-Controlled Trial to Evaluate Efficacy and Safety of Romosozumab in Men with Osteoporosis. Journal of Clinical Endocrinology and Metabolism 103(9): 3183-3193
Benjamin, D.K.; Kaufman, D.A.; Hope, W.W.; Smith, P.B.; Arrieta, A.; Manzoni, P.; Kovanda, L.L.; Lademacher, C.; Isaacson, B.; Jednachowski, D.; Wu, C.; Kaibara, A.; Walsh, T.J. 2018: A Phase 3 Study of Micafungin Versus Amphotericin B Deoxycholate in Infants with Invasive Candidiasis. Pediatric Infectious Disease Journal 37(10): 992-998
Niihara, Y.; Miller, S.T.; Kanter, J.; Lanzkron, S.; Smith, W.R.; Hsu, L.L.; Gordeuk, V.R.; Viswanathan, K.; Sarnaik, S.; Osunkwo, I.; Guillaume, E.; Sadanandan, S.; Sieger, L.; Lasky, J.L.; Panosyan, E.H.; Blake, O.A.; New, T.N.; Bellevue, R.; Tran, L.T.; Razon, R.L.; Stark, C.W.; Neumayr, L.D.; Vichinsky, E.P.; O'Neal, P.; Haynes, J.; Labotka, R.; Sharon, B.; McMahon, L.; Kruse-Jarres, R.; Kerr, J.; Moulton, T.; Hassell, K.; Dunbar, L.; Hussein, A.; Woods, G.; Osarogiagbon, R.; Goyal-Khemka, M.; Ferber, A.; Iyer, R.; Smith, M.; Majumdar, S.; Raj, A.; Puthenveetil, G.; Bryant, P.; Abdul Rashid, N.; Ikeda, A. 2018: A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. New England Journal of Medicine 379(3): 226-235
Kern, R.C.; Stolovitzky, J.P.; Silvers, S.L.; Singh, A.; Lee, J.T.; Yen, D.M.; Iloreta, A.M.C.; Langford, F.P.J.; Karanfilov, B.; Matheny, K.E.; Stambaugh, J.W.; Gawlicka, A.K. 2018: A phase 3 trial of mometasone furoate sinus implants for chronic sinusitis with recurrent nasal polyps. International Forum of Allergy and Rhinology 8(4): 471-481
Ella, R.; Bobba, R.; Muralidhar, S.; Babji, S.; Vadrevu, K.Mohan.; Bhan, M.Kishan. 2018: A Phase 4, multicentre, randomized, single-blind clinical trial to evaluate the immunogenicity of the live, attenuated, oral rotavirus vaccine (116E), ROTAVAC®, administered simultaneously with or without the buffering agent in healthy infants in India. Human Vaccines and Immunotherapeutics 14(7): 1791-1799
Shin, J.; Koh, Y.; Yoon, S.H.; Cho, J.-Y.; Kim, D.-Y.; Lee, K.-H.; Kim, H.-J.; Ahn, J.-S.; Kim, Y.-K.; Park, J.; Sohn, S.-K.; Moon, J.H.; Lee, Y.J.; Yoon, S.; Lee, J.-O.; Cheong, J.-W.; Kim, K.H.; Kim, S.-H.; Kim, H.-G.; Kim, H.; Nam, S.-H.; Do, Y.R.; Park, S.-G.; Park, S.K.; Bae, S.H.; Song, H.H.; Shin, D.-Y.; Oh, D.; Kim, M.K.; Jung, C.W.; Park, S.; Kim, I. 2018: A phase 4 study of nilotinib in Korean patients with Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase: ENESTKorea. Cancer Medicine 7(5): 1814-1823
Dodick, D.W. 2018: A Phase-by-Phase Review of Migraine Pathophysiology. Headache 58(Suppl 1): 4-16
Wang, N.; Kocher, G.; Provatas, N. 2018: A phase-field-crystal alloy model for late-stage solidification studies involving the interaction of solid, liquid and gas phases. Philosophical Transactions. Series a Mathematical Physical and Engineering Sciences 376(2113)
Ueno, H.; Kondo, S.; Yoshikawa, S.; Inoue, K.; Andre, V.ér.; Tajimi, M.; Murakami, H. 2018: A phase i and pharmacokinetic study of taladegib, a Smoothened inhibitor, in Japanese patients with advanced solid tumors. Investigational new Drugs 36(4): 647-656
Subramaniam, D.S.; Liu, S.V.; Crawford, J.; Kramer, J.; Thompson, J.; Wang, H.; Giaccone, G. 2018: A Phase Ib/Ii Study of Ganetespib with Doxorubicin in Advanced Solid Tumors Including Relapsed-Refractory Small Cell Lung Cancer. Frontiers in Oncology 8: 64
Beatty, G.L.; Shahda, S.; Beck, T.; Uppal, N.; Cohen, S.J.; Donehower, R.; Gabayan, A.E.; Assad, A.; Switzky, J.; Zhen, H.; Von Hoff, D.D. 2019: A Phase Ib/Ii Study of the JAK1 Inhibitor, Itacitinib, plus nab-Paclitaxel and Gemcitabine in Advanced Solid Tumors. Oncologist 24(1): 14-E10
Kelly, C.M.; Shoushtari, A.N.; Qin, L.-X.; D'Angelo, S.P.; Dickson, M.A.; Gounder, M.M.; Keohan, M.L.; Mcfadyen, C.; Sjoberg, A.; Singer, S.; DeMatteo, R.P.; Hwang, S.; Heinemann, M.H.; Francis, J.H.; Antonescu, C.R.; Chi, P.; Tap, W.D. 2019: A phase Ib study of BGJ398, a pan-FGFR kinase inhibitor in combination with imatinib in patients with advanced gastrointestinal stromal tumor. Investigational new Drugs 37(2): 282-290
Bauer, T.M.; Patel, M.R.; Forero-Torres, A.; George, T.J.; Assad, A.; Du, Y.; Hurwitz, H. 2018: A Phase Ib study of ruxolitinib + gemcitabine ± nab-paclitaxel in patients with advanced solid tumors. Oncotargets and Therapy 11: 2399-2407
Ruiz-Borrego, M.; Jimenez, B.ña.; Antolín, S.; García-Saenz, J.A.; Corral, J.ús.; Jerez, Y.; Trigo, J.é; Urruticoechea, A.; Colom, H.; Gonzalo, N.; Muñoz, C.; Benito, S.; Caballero, R.ía.; Bezares, S.; Carrasco, E.; Rojo, F.; Martín, M. 2019: A phase Ib study of sonidegib (LDE225), an oral small molecule inhibitor of smoothened or Hedgehog pathway, in combination with docetaxel in triple negative advanced breast cancer patients: GEICAM/2012-12 (EDALINE) study. Investigational new Drugs 37(1): 98-108
Méndez, E.; Rodriguez, C.P.; Kao, M.C.; Raju, S.; Diab, A.; Harbison, R.A.; Konnick, E.Q.; Mugundu, G.M.; Santana-Davila, R.; Martins, R.; Futran, N.D.; Chow, L.Q.M. 2018: A Phase i Clinical Trial of AZD1775 in Combination with Neoadjuvant Weekly Docetaxel and Cisplatin before Definitive Therapy in Head and Neck Squamous Cell Carcinoma. Clinical Cancer Research: An Official Journal of the American Association for Cancer Research 24(12): 2740-2748
Stemmer, S.M.; Benjaminov, O.; Silverman, M.H.; Sandler, U.; Purim, O.; Sender, N.; Meir, C.; Oren-Apoteker, P.; Ohana, J.; Devary, Y. 2018: A phase i clinical trial of dTCApFs, a derivative of a novel human hormone peptide, for the treatment of advanced/metastatic solid tumors. Molecular and Clinical Oncology 8(1): 22-29
Hirooka, Y.; Kasuya, H.; Ishikawa, T.; Kawashima, H.; Ohno, E.; Villalobos, I.B.; Naoe, Y.; Ichinose, T.; Koyama, N.; Tanaka, M.; Kodera, Y.; Goto, H. 2018: A Phase i clinical trial of EUS-guided intratumoral injection of the oncolytic virus, HF10 for unresectable locally advanced pancreatic cancer. Bmc Cancer 18(1): 596
Hijikata, Y.; Okazaki, T.; Tanaka, Y.; Murahashi, M.; Yamada, Y.; Yamada, K.; Takahashi, A.; Inoue, H.; Kishimoto, J.; Nakanishi, Y.; Oda, Y.; Nakamura, Y.; Tani, K. 2018: A phase i clinical trial of RNF43 peptide-related immune cell therapy combined with low-dose cyclophosphamide in patients with advanced solid tumors. Plos one 13(1): E0187878
Predina, J.D.; Newton, A.D.; Keating, J.; Dunbar, A.; Connolly, C.; Baldassari, M.; Mizelle, J.; Xia, L.; Deshpande, C.; Kucharczuk, J.; Low, P.S.; Singhal, S. 2018: A Phase i Clinical Trial of Targeted Intraoperative Molecular Imaging for Pulmonary Adenocarcinomas. Annals of Thoracic Surgery 105(3): 901-908
Brown, D.; Daniels, K.; Pichereau, S.; Sand, M. 2018: A Phase IC Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Cognitive Outcomes of Bi 409306 in Patients with Mild-to-Moderate Schizophrenia. Neurology and Therapy 7(1): 129-139
Foss, F.M.; Parker, T. 2018: A Phase i Dose-Escalation Study of Clofarabine in Patients with Relapsed or Refractory Low-Grade or Intermediate-Grade B-Cell or T-Cell Lymphoma. Oncologist 23(4): 397-E30
Sahin, U.; Schuler, M.; Richly, H.; Bauer, S.; Krilova, A.; Dechow, T.; Jerling, M.; Utsch, M.; Rohde, C.; Dhaene, K.; Huber, C.; Türeci, Öz. 2018: A phase i dose-escalation study of IMAB362 (Zolbetuximab) in patients with advanced gastric and gastro-oesophageal junction cancer. European Journal of Cancer 100: 17-26
Davis, S.Lindsey.; Eckhardt, S.Gail.; Diamond, J.R.; Messersmith, W.A.; Dasari, A.; Weekes, C.D.; Lieu, C.H.; Kane, M.; Choon Tan, A.; Pitts, T.M.; Leong, S. 2018: A Phase I Dose-Escalation Study of Linsitinib (OSI-906), a Small-Molecule Dual Insulin-Like Growth Factor-1 Receptor/Insulin Receptor Kinase Inhibitor, in Combination with Irinotecan in Patients with Advanced Cancer. Oncologist 23(12): 1409-E140
Shabason, J.E.; Chen, J.; Apisarnthanarax, S.; Damjanov, N.; Giantonio, B.; Loaiza-Bonilla, A.; O'Dwyer, P.J.; O'Hara, M.; Reiss, K.A.; Teitelbaum, U.; Wissel, P.; Drebin, J.A.; Vollmer, C.; Kochman, M.; Mick, R.; Vergara, N.; Jhala, N.; Doucette, A.; Lukens, J.N.; Plastaras, J.P.; Metz, J.M.; Ben-Josef, E. 2018: A phase i dose escalation trial of nab-paclitaxel and fixed dose radiation in patients with unresectable or borderline resectable pancreatic cancer. Cancer ChemoTherapy and Pharmacology 81(3): 609-614
Mercier, C.; Dirix, P.; Meijnders, P.; Vermeulen, P.; Van Laere, S.; Debois, H.; Huget, P.; Verellen, D. 2018: A phase i dose-escalation trial of stereotactic ablative body radiotherapy for non-spine bone and lymph node metastases (DESTROY-trial). Radiation Oncology 13(1): 152
Swystun, V.; Green, F.H.Y.; Dennis, J.H.; Rampakakis, E.; Lalli, G.; Fadayomi, M.; Chiu, A.; Shrestha, G.; El Shahat, S.G.; Nelson, D.E.; El Mays, T.Y.; Pieron, C.A.; Leigh, R. 2018: A phase IIa proof-of-concept, placebo-controlled, randomized, double-blind, crossover, single-dose clinical trial of a new class of bronchodilator for acute asthma. Trials 19(1): 321
Alamgeer, M.; Neil Watkins, D.; Banakh, I.; Kumar, B.; Gough, D.J.; Markman, B.; Ganju, V. 2018: A phase IIa study of HA-irinotecan, formulation of hyaluronic acid and irinotecan targeting CD44 in extensive-stage small cell lung cancer. Investigational new Drugs 36(2): 288-298
Bao, T.; Seidman, A.D.; Piulson, L.; Vertosick, E.; Chen, X.; Vickers, A.J.; Blinder, V.S.; Zhi, W.I.; Li, Q.; Vahdat, L.T.; Dickler, M.N.; Robson, M.E.; Mao, J.J. 2018: A phase IIA trial of acupuncture to reduce chemotherapy-induced peripheral neuropathy severity during neoadjuvant or adjuvant weekly paclitaxel chemotherapy in breast cancer patients. European Journal of Cancer 101: 12-19
Gold, J.; Marta, M.; Meier, U.C.; Christensen, T.; Miller, D.; Altmann, D.; Holden, D.; Bianchi, L.; Adiutori, R.; MacManus, D.; Yousry, T.; Schmierer, K.; Turner, B.; Giovannoni, G. 2018: A phase II baseline versus treatment study to determine the efficacy of raltegravir (Isentress) in preventing progression of relapsing remitting multiple sclerosis as determined by gadolinium-enhanced MRI: The INSPIRE study. Multiple Sclerosis and Related Disorders 24: 123-128
Kerwin, E.M.; Spangenthal, S.; Kollar, C.; St Rose, E.; Reisner, C. 2018: A phase IIb randomized, chronic-dosing, incomplete block, cross-over study of glycopyrronium, delivered via metered dose inhaler, compared with a placebo and an active control in patients with moderate-to-severe COPD. Respiratory Research 19(1): 38
Sundar, R.; Rha, S.Y.; Yamaue, H.; Katsuda, M.; Kono, K.; Kim, H.S.; Kim, C.; Mimura, K.; Kua, L.-F.; Yong, W.P. 2018: A phase I/Ib study of OTSGC-A24 combined peptide vaccine in advanced gastric cancer. Bmc Cancer 18(1): 332
Wu, F.; Zhang, S.; Xiong, A.; Gao, G.; Li, W.; Cai, W.; Su, C.; Chen, X.; Zhou, F.; Zhao, J.; Ren, S.; Zhou, C. 2018: A Phase Ii Clinical Trial of Apatinib in Pretreated Advanced Non-squamous Non-small-cell Lung Cancer. Clinical Lung Cancer 19(6): E831-E842
Tsai, S.; Christians, K.K.; George, B.; Ritch, P.S.; Dua, K.; Khan, A.; Mackinnon, A.C.; Tolat, P.; Ahmad, S.A.; Hall, W.A.; Erickson, B.A.; Evans, D.B. 2018: A Phase Ii Clinical Trial of Molecular Profiled Neoadjuvant Therapy for Localized Pancreatic Ductal Adenocarcinoma. Annals of Surgery 268(4): 610-619
Diamond, J.R.; Eckhardt, S.G.; Pitts, T.M.; van Bokhoven, A.; Aisner, D.; Gustafson, D.L.; Capasso, A.; Sams, S.; Kabos, P.; Zolman, K.; Colvin, T.; Elias, A.D.; Storniolo, A.M.; Schneider, B.P.; Gao, D.; Tentler, J.J.; Borges, V.F.; Miller, K.D. 2018: A phase Ii clinical trial of the Aurora and angiogenic kinase inhibitor ENMD-2076 for previously treated, advanced, or metastatic triple-negative breast cancer. Breast Cancer Research: Bcr 20(1): 82
Chan, J.K.; Brady, W.; Monk, B.J.; Brown, J.; Shahin, M.S.; Rose, P.G.; Kim, J.-H.; Secord, A.A.; Walker, J.L.; Gershenson, D.M. 2018: A phase Ii evaluation of sunitinib in the treatment of persistent or recurrent clear cell ovarian carcinoma: An NRG Oncology/Gynecologic Oncology Group Study (GOG-254). Gynecologic Oncology 150(2): 247-252
Enblad, G.; Karlsson, H.; Gammelgård, G.; Wenthe, J.; Lövgren, T.; Amini, R.M.; Wikstrom, K.I.; Essand, M.; Savoldo, B.; Hallböök, H.; Höglund, M.; Dotti, G.; Brenner, M.K.; Hagberg, H.; Loskog, A. 2018: A Phase I/IIa Trial Using CD19-Targeted Third-Generation CAR T Cells for Lymphoma and Leukemia. Clinical Cancer Research: An Official Journal of the American Association for Cancer Research 24(24): 6185-6194
Boelaert, M.; Mukendi, D.; Bottieau, E.; Kalo Lilo, J.R.; Verdonck, K.; Minikulu, L.; Barbé, B.; Gillet, P.; Yansouni, C.éd.P.; Chappuis, F.ço.; Lutumba, P. 2018: A Phase IIi Diagnostic Accuracy Study of a Rapid Diagnostic Test for Diagnosis of Second-Stage Human African Trypanosomiasis in the Democratic Republic of the Congo. Ebiomedicine 27: 11-17
San-Miguel, J.ús.F.; Echeveste Gutierrez, M.-A.ón.; Špicka, I.; Mateos, M.ía.-V.; Song, K.; Craig, M.D.; Bladé, J.; Hájek, R.; Chen, C.; Di Bacco, A.; Estevam, J.; Gupta, N.; Byrne, C.; Lu, V.; van de Velde, H.; Lonial, S. 2018: A phase I/Ii dose-escalation study investigating all-oral ixazomib-melphalan-prednisone induction followed by single-agent ixazomib maintenance in transplant-ineligible newly diagnosed multiple myeloma. Haematologica 103(9): 1518-1526
Jordan, S.C.; Choi, J.; Aubert, O.; Haas, M.; Loupy, A.; Huang, E.; Peng, A.; Kim, I.; Louie, S.; Ammerman, N.; Najjar, R.; Puliyanda, D.; Vo, A. 2018: A phase I/II, double-blind, placebo-controlled study assessing safety and efficacy of C1 esterase inhibitor for prevention of delayed graft function in deceased donor kidney transplant recipients. American Journal of Transplantation: Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons 18(12): 2955-2964
Carpenter, P.A.; Logan, B.R.; Lee, S.J.; Weisdorf, D.J.; Johnston, L.; Costa, L.J.; Kitko, C.L.; Bolaños-Meade, J.; Sarantopoulos, S.; Alousi, A.M.; Abhyankar, S.; Waller, E.K.; Mendizabal, A.; Zhu, J.; O'Brien, K.A.; Lazaryan, A.; Wu, J.; Nemecek, E.R.; Pavletic, S.Z.; Cutler, C.S.; Horowitz, M.M.; Arora, M. 2018: A phase II/IIi randomized, multicenter trial of prednisone/sirolimus versus prednisone/ sirolimus/calcineurin inhibitor for the treatment of chronic graft-versus-host disease: BMT CTN 0801. Haematologica 103(11): 1915-1924
Hong, S.J.; Jeong, H.S.; Ahn, J.C.; Cha, D.-H.; Won, K.H.; Kim, W.; Cho, S.K.; Kim, S.-Y.; Yoo, B.-S.; Sung, K.C.; Rha, S.-W.; Shin, J.-H.; Han, K.R.; Chung, W.S.; Hyon, M.S.; Lee, H.C.; Bae, J.-H.; Rhee, M.-Y.; Kwan, J.; Jeon, D.W.; Yoo, K.D.; Kim, H.-S. 2018: A Phase III, Multicenter, Randomized, Double-blind, Active Comparator Clinical Trial to Compare the Efficacy and Safety of Combination Therapy with Ezetimibe and Rosuvastatin Versus Rosuvastatin Monotherapy in Patients with Hypercholesterolemia: I-ROSETTE (Ildong Rosuvastatin and Ezetimibe for Hypercholesterolemia) Randomized Controlled Trial. Clinical Therapeutics 40(2): 226-241.E4
Rakugi, H.; Shimizu, K.; Nishiyama, Y.; Sano, Y.; Umeda, Y. 2018: A phase III, open-label, multicenter study to evaluate the safety and efficacy of long-term triple combination therapy with azilsartan, amlodipine, and hydrochlorothiazide in patients with essential hypertension. Blood Pressure 27(3): 125-133
Marlow, R.; Kuriyakose, S.; Mesaros, N.; Han, H.H.; Tomlinson, R.; Faust, S.N.; Snape, M.D.; Pollard, A.J.; Finn, A. 2018: A phase III, open-label, randomised multicentre study to evaluate the immunogenicity and safety of a booster dose of two different reduced antigen diphtheria-tetanus-acellular pertussis-polio vaccines, when co-administered with measles-mumps-rubella vaccine in 3 and 4-year-old healthy children in the UK. Vaccine 36(17): 2300-2306
Sculier, J.-P.; Lafitte, J.-J.; Berghmans, T.; Meert, A.-P.; Scherpereel, A.; Roelandts, M.; Van Cutsem, O.; Colinet, B.; Bonduelle, Y.; Giner, V.; Paesmans, M.; Leclercq, N.; Van Houtte, P. 2018: A phase IIi randomised study comparing concomitant radiochemotherapy with cisplatin and docetaxel as induction versus consolidation treatment in patients with locally advanced unresectable non-small cell lung cancer. Lung Cancer 117: 32-37
Gómez-Aguayo, F.; Paczka, J.é A.; Leñero-Córdova, R.én.; Jiménez-Román, J.ús.; Davila-Villarreal, J.; Hartleben, C.; Baiza-Durán, L.; Olvera-Montaño, O.; García-Velez, F.; Muñoz-Villegas, P. 2018: A Phase IIi Randomized Clinical Trial of a 0.5% Timolol + 0.2% Brimonidine + 2.0% Dorzolamide Fixed Combination, Preservative-Free Ophthalmic Solution vs. 0.5% Timolol + 0.2% Brimonidine + 2.0% Dorzolamide Fixed Combination in Patients with Controlled Primary Open-Angle Glaucoma. Ophthalmology and Therapy 7(1): 145-156
Ahmadi, H.; Jamshidi, A.R.; Gharibdoost, F.; Mahmoudi, M.; Rastkari, N.; Mostafaei, S.; Fattahi, M.J.; Vojdanian, M.; Cuzzocrea, S.; Rehm, B.H.A.; Matsuo, H.; Hosseini, M.; Aghazadeh, Z.; Mortazavi-Jahromi, S.S.; Mirshafiey, A. 2018: A phase I/Ii randomized, controlled, clinical trial for assessment of the efficacy and safety of β-D-mannuronic acid in rheumatoid arthritis patients. Inflammopharmacology 26(3): 737-745
Ostrowitzki, S.; Lasser, R.A.; Dorflinger, E.; Scheltens, P.; Barkhof, F.; Nikolcheva, T.; Ashford, E.; Retout, S.; Hofmann, C.; Delmar, P.; Klein, G.; Andjelkovic, M.; Dubois, B.; Boada, M.è; Blennow, K.; Santarelli, L.; Fontoura, P. 2017: A phase IIi randomized trial of gantenerumab in prodromal Alzheimer's disease. Alzheimer's Research and Therapy 9(1): 95
Pivot, X.; Bondarenko, I.; Nowecki, Z.; Dvorkin, M.; Trishkina, E.; Ahn, J-H.; Im, S-A.; Sarosiek, T.; Chatterjee, S.; Wojtukiewicz, M.Z.; Shparyk, Y.; Moiseyenko, V.; Bello, M.; Semiglazov, V.; Lee, Y.; Lim, J. 2018: A phase III study comparing SB3 (a proposed trastuzumab biosimilar) and trastuzumab reference product in HER2-positive early breast cancer treated with neoadjuvant-adjuvant treatment: Final safety, immunogenicity and survival results. European Journal of Cancer 93: 19-27
Rex, D.K.; Bhandari, R.; Desta, T.; DeMicco, M.P.; Schaeffer, C.; Etzkorn, K.; Barish, C.F.; Pruitt, R.; Cash, B.D.; Quirk, D.; Tiongco, F.; Sullivan, S.; Bernstein, D. 2018: A phase IIi study evaluating the efficacy and safety of remimazolam (CNS 7056) compared with placebo and midazolam in patients undergoing colonoscopy. Gastrointestinal Endoscopy 88(3): 427-437.E6
Ri, M.; Suzuki, K.; Iida, S.; Hatake, K.; Chou, T.; Taniwaki, M.; Watanabe, N.; Tsukamoto, T. 2018: A Phase I/Ii Study for Dose-finding, and to Investigate the Safety, Pharmacokinetics and Preliminary Efficacy of NK012, an SN-38-Incorporating Macromolecular Polymeric Micelle, in Patients with Multiple Myeloma. Internal Medicine 57(7): 939-946
Sekimizu, M.; Osumi, T.; Fukano, R.; Koga, Y.; Kada, A.; Saito, A.M.; Mori, T. 2018: A Phase I/Ii Study of Crizotinib for Recurrent or Refractory Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma and a Phase i Study of Crizotinib for Recurrent or Refractory Neuroblastoma : Study Protocol for a Multicenter Single-arm Open-label Trial. Acta Medica Okayama 72(4): 431-436
Tanaka, Y.; Ueda, Y.; Nakagawa, S.; Matsuzaki, S.; Kobayashi, E.; Shiki, Y.; Nishio, Y.; Takemura, M.; Yamamoto, T.; Sawada, K.; Tomimatsu, T.; Yoshino, K.; Kimura, T. 2018: A phase I/II study of GLIF combination chemotherapy for taxane/platinum-refractory/resistant endometrial cancer (GOGO-EM2). Cancer ChemoTherapy and Pharmacology 82(4): 585-592
Martínez-Cuadrón, D.; Boluda, B.; Martínez, P.; Bergua, J.; Rodríguez-Veiga, R.; Esteve, J.; Vives, S.; Serrano, J.; Vidriales, B.; Salamero, O.; Cordón, L.; Sempere, A.; Jiménez-Ubieto, A.; Prieto-Delgado, J.; Díaz-Beyá, M.; Garrido, A.; Benavente, C.; Pérez-Simón, J.é A.; Moscardó, F.; Sanz, M.A.; Montesinos, P. 2018: A phase I-Ii study of plerixafor in combination with fludarabine, idarubicin, cytarabine, and G-CSF (PLERIFLAG regimen) for the treatment of patients with the first early-relapsed or refractory acute myeloid leukemia. Annals of Hematology 97(5): 763-772
Chen, T.W.-W.; Yeh, D.-C.; Chao, T.-Y.; Lin, C.-H.; Chow, L.W.-C.; Chang, D.-Y.; Hsieh, Y.-Y.; Huang, S.-M.; Cheng, A.-L.; Lu, Y.-S.; Consortium, T.B.C. 2018: A Phase I/Ii study of the combination of lapatinib and oral vinorelbine in HER2-positive metastatic breast cancer. Japanese Journal of Clinical Oncology 48(3): 242-247
Monga, V.; Swami, U.; Tanas, M.; Bossler, A.; Mott, S.L.; Smith, B.J.; Milhem, M. 2018: A Phase I/Ii Study Targeting Angiogenesis Using Bevacizumab Combined with Chemotherapy and a Histone Deacetylase Inhibitor (Valproic Acid) in Advanced Sarcomas. Cancers 10(2)
Lee, K-Wook.; Maeng, C.Hoon.; Kim, T-You.; Zang, D.Young.; Kim, Y.Hong.; Hwang, I.Gyu.; Oh, S.Cheul.; Chung, J.Seop.; Song, H.Suk.; Kim, J.Won.; Jeong, S.Jin.; Cho, J.Yong. 2019: A Phase III Study to Compare the Efficacy and Safety of Paclitaxel Versus Irinotecan in Patients with Metastatic or Recurrent Gastric Cancer Who Failed in First-line Therapy (KCSG ST10-01). Oncologist 24(1): 18-E24
Tamiya, A.; Morimoto, M.; Fukuda, S.; Naoki, Y.; Ibe, T.; Okishio, K.; Goto, H.; Yoshii, A.; Kita, T.; Nogami, N.; Fujita, Y.; Atagi, S. 2018: A phase I/Ii trial of pemetrexed plus radiotherapy in elderly patients with locally advanced non-small cell lung cancer. Investigational new Drugs 36(4): 667-673
Medeiros, B.C.; Tanaka, T.N.; Balaian, L.; Bashey, A.; Guzdar, A.; Li, H.; Messer, K.; Ball, E.D. 2018: A Phase I/Ii Trial of the Combination of Azacitidine and Gemtuzumab Ozogamicin for Treatment of Relapsed Acute Myeloid Leukemia. Clinical Lymphoma Myeloma and Leukemia 18(5): 346-352.E5
Kimura, K.; Iwamoto, M.; Tanaka, S.; Yamamoto, D.; Yoshidome, K.; Ogura, H.; Terasawa, R.; Matsunami, N.; Takahashi, Y.; Nitta, T.; Morimoto, T.; Fujioka, H.; Kawaguchi, K.; Uchiyama, K. 2018: A phase II, multicenter, single-arm trial of eribulin as first- or second-line chemotherapy for HER2-negative advanced or metastatic breast cancer: evaluation of efficacy, safety, and patient-reported outcomes. Cancer ChemoTherapy and Pharmacology 81(5): 923-933
Mrowietz, U.; Kedem, T.H.; Keynan, R.; Eini, M.; Tamarkin, D.; Rom, D.; Shirvan, M. 2018: A Phase II, Randomized, Double-Blind Clinical Study Evaluating the Safety, Tolerability, and Efficacy of a Topical Minocycline Foam, FMX103, for the Treatment of Facial Papulopustular Rosacea. American Journal of Clinical Dermatology 19(3): 427-436
Klotz, L.; Loblaw, A.; Siemens, R.; Ouellette, P.; Kapoor, A.; Kebabdjian, M.; Zhang, L.; Saad, F. 2018: A Phase II, Randomized, Multicenter Study Comparing 10 Months versus 4 Months of Degarelix Therapy in Prolonging the Off Treatment Interval in Men with Localized Prostate Cancer Receiving Intermittent Androgen Deprivation Therapy for Biochemical Recurrence following Radical Local Therapy. Journal of Urology 200(2): 335-343
Kalimuddin, S.; Wijaya, L.; Chan, Y.F.Z.; Wong, A.W.L.; Oh, H.M.L.; Wang, L.-F.; Kassim, J.A.; Zhao, J.; Shi, Z.; Low, J.G. 2017: A phase Ii randomized study to determine the safety and immunogenicity of the novel PIKA rabies vaccine containing the PIKA adjuvant using an accelerated regimen. Vaccine 35(51): 7127-7132
Huang, P.-W.; Lin, C.-Y.; Hsieh, C.-H.; Hsu, C.-L.; Fan, K.-H.; Huang, S.-F.; Liao, C.-T.; Ng, S.-K.; Yen, T.-C.; Chang, J.T.-C.; Wang, H.-M. 2018: A phase Ii randomized trial comparing neoadjuvant chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in advanced squamous cell carcinoma of the pharynx or larynx. Biomedical Journal 41(2): 129-136
Santa-Maria, C.A.; Bardia, A.; Blackford, A.L.; Snyder, C.; Connolly, R.M.; Fetting, J.H.; Hayes, D.F.; Jeter, S.C.; Miller, R.S.; Nguyen, A.; Quinlan, K.; Rosner, G.L.; Slater, S.; Storniolo, A.Maria.; Wolff, A.C.; Zorzi, J.; Henry, N.Lynn.; Stearns, V. 2018: A phase II study evaluating the efficacy of zoledronic acid in prevention of aromatase inhibitor-associated musculoskeletal symptoms: the ZAP trial. Breast Cancer Research and Treatment 171(1): 121-129
Takekuma, M.; Shimokawa, M.; Nishio, S.; Omi, H.; Tabata, T.; Takei, Y.; Nasu, K.; Takahashi, Y.; Toyota, S.; Ichikawa, Y.; Arakawa, A.; Ito, F.; Tsubamoto, H.; Mori, T.; Hirashima, Y.; Ito, K. 2018: Phase Ii study of adjuvant chemotherapy with paclitaxel and nedaplatin for uterine cervical cancer with lymph node metastasis. Cancer Science 109(5): 1602-1608
Miao, M.; Deng, G.; Luo, S.; Zhou, J.; Chen, L.; Yang, J.; He, J.; Li, J.; Yao, J.; Tan, S.; Tang, J. 2018: A phase Ii study of apatinib in patients with recurrent epithelial ovarian cancer. Gynecologic Oncology 148(2): 286-290
Matsuda, C.; Honda, M.; Tanaka, C.; Kondo, K.; Takahashi, T.; Kosugi, C.; Tokunaga, Y.; Takemoto, H.; Kim, H.Min.; Sakamoto, J.; Oba, K.; Mishima, H. 2018: A phase II study of bevacizumab and irinotecan plus alternate-day S-1 as a second-line therapy in patients with metastatic colorectal cancer: the AIRS study. Cancer ChemoTherapy and Pharmacology 81(6): 1035-1041
Takashina, T.; Asahina, H.; Oizumi, S.; Yamada, N.; Harada, M.; Takamura, K.; Yokouchi, H.; Harada, T.; Honjo, O.; Ogi, T.; Morikawa, N.; Kinoshita, I.; Honda, R.; Nakano, K.; Kanazawa, K.; Amano, T.; Dosaka-Akita, H.; Isobe, H.; Nishimura, M. 2018: A phase Ii study of carboplatin, pemetrexed, and bevacizumab followed by erlotinib and bevacizumab maintenance for non-squamous non-small cell lung cancer with wild-type EGFR (HOT1101). International Journal of Clinical Oncology 23(6): 1060-1069
Lee, H.J.; Badillo, M.; Romaguera, J.; Wang, M. 2019: A phase Ii study of carfilzomib in the treatment of relapsed/refractory mantle cell lymphoma. British Journal of Haematology 184(3): 460-462
Chen, E.Y.; Blanke, C.D.; Haller, D.G.; Benson, A.B.; Dragovich, T.; Lenz, H-Josef.; Robles, C.; Li, H.; Mori, M.; Mattek, N.; Sanborn, R.E.; Lopez, C.D. 2018: A Phase II Study of Celecoxib With Irinotecan, 5-Fluorouracil, and Leucovorin in Patients With Previously Untreated Advanced or Metastatic Colorectal Cancer. American Journal of Clinical Oncology 41(12): 1193-1198
Mooradian, M.J.; Reuben, A.; Prieto, P.A.; Hazar-Rethinam, M.; Frederick, D.T.; Nadres, B.; Piris, A.; Juneja, V.; Cooper, Z.A.; Sharpe, A.H.; Corcoran, R.B.; Flaherty, K.T.; Lawrence, D.P.; Wargo, J.A.; Sullivan, R.J. 2018: A phase II study of combined therapy with a BRAF inhibitor (vemurafenib) and interleukin-2 (aldesleukin) in patients with metastatic melanoma. Oncoimmunology 7(5): E1423172
Aghajanian, C.; Filiaci, V.; Dizon, D.S.; Carlson, J.W.; Powell, M.A.; Secord, A.A.; Tewari, K.S.; Bender, D.P.; O'Malley, D.M.; Stuckey, A.; Gao, J.; Dao, F.; Soslow, R.A.; Lankes, H.A.; Moore, K.; Levine, D.A. 2018: A phase Ii study of frontline paclitaxel/carboplatin/bevacizumab, paclitaxel/carboplatin/temsirolimus, or ixabepilone/carboplatin/bevacizumab in advanced/recurrent endometrial cancer. Gynecologic Oncology 150(2): 274-281
Yokota, T.; Hamauchi, S.; Yoshida, Y.; Yurikusa, T.; Suzuki, M.; Yamashita, A.; Ogawa, H.; Onoe, T.; Mori, K.; Onitsuka, T. 2018: A phase Ii study of HMB/Arg/Gln against oral mucositis induced by chemoradiotherapy for patients with head and neck cancer. Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer 26(9): 3241-3248
Kondo, R.; Watanabe, S.; Shoji, S.; Ichikawa, K.; Abe, T.; Baba, J.; Tanaka, J.; Tsukada, H.; Terada, M.; Sato, K.; Maruyama, Y.; Makino, M.; Hirata, A.; Tanaka, H.; Koya, T.; Yoshizawa, H.; Kikuchi, T. 2018: A Phase II Study of Irinotecan for Patients with Previously Treated Small-Cell Lung Cancer. Oncology 94(4): 223-232
Ozaka, M.; Ishii, H.; Sato, T.; Ueno, M.; Ikeda, M.; Uesugi, K.; Sata, N.; Miyashita, K.; Mizuno, N.; Tsuji, K.; Okusaka, T.; Furuse, J. 2018: A phase Ii study of modified FOLFIRINOX for chemotherapy-naïve patients with metastatic pancreatic cancer. Cancer ChemoTherapy and Pharmacology 81(6): 1017-1023
Bando, H.; Shimodaira, H.; Fujitani, K.; Takashima, A.; Yamaguchi, K.; Nakayama, N.; Takahashi, T.; Oki, E.; Azuma, M.; Nishina, T.; Hironaka, S.; Komatsu, Y.; Shitara, K. 2018: A phase Ii study of nab-paclitaxel in combination with ramucirumab in patients with previously treated advanced gastric cancer. European Journal of Cancer 91: 86-91
Mahalingam, D.; Goel, S.; Aparo, S.; Patel Arora, S.; Noronha, N.; Tran, H.; Chakrabarty, R.; Selvaggi, G.; Gutierrez, A.; Coffey, M.; Nawrocki, S.T.; Nuovo, G.; Mita, M.M. 2018: A Phase Ii Study of Pelareorep (REOLYSIN®) in Combination with Gemcitabine for Patients with Advanced Pancreatic Adenocarcinoma. Cancers 10(6)
Lisberg, A.; Cummings, A.; Goldman, J.W.; Bornazyan, K.; Reese, N.; Wang, T.; Coluzzi, P.; Ledezma, B.; Mendenhall, M.; Hunt, J.; Wolf, B.; Jones, B.; Madrigal, J.; Horton, J.; Spiegel, M.; Carroll, J.; Gukasyan, J.; Williams, T.; Sauer, L.; Wells, C.; Hardy, A.; Linares, P.; Lim, C.; Ma, L.; Adame, C.; Garon, E.B. 2018: A Phase Ii Study of Pembrolizumab in EGFR-Mutant, PD-L1+, Tyrosine Kinase Inhibitor Naïve Patients with Advanced NSCLC. Journal of Thoracic Oncology: Official Publication of the International Association for the Study of Lung Cancer 13(8): 1138-1145
Gbolahan, O.B.; Porter, R.F.; Salter, J.T.; Yiannoutsos, C.; Burns, M.; Chiorean, E.G.; Loehrer, P.J. 2018: A Phase Ii Study of Pemetrexed in Patients with Recurrent Thymoma and Thymic Carcinoma. Journal of Thoracic Oncology: Official Publication of the International Association for the Study of Lung Cancer 13(12): 1940-1948
Modi, D.; Al-Kadhimi, Z.; Chen, W.; Jang, H.; Deol, A.; Ayash, L.; Bhutani, D.; Alavi, A.; Ratanatharathorn, V.; Uberti, J.P. 2018: A phase Ii study of tacrolimus and thymoglobulin as graft-versus-host-disease prophylaxis in related donor allogeneic hematopoietic cell transplantation. American Journal of Hematology 93(4): E96-E98
Dunn, L.A.; Fury, M.G.; Xiao, H.; Baxi, S.S.; Sherman, E.J.; Korte, S.; Pfister, C.; Haque, S.; Katabi, N.; Ho, A.L.; Pfister, D.G. 2018: A phase Ii study of temsirolimus added to low-dose weekly carboplatin and paclitaxel for patients with recurrent and/or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC). Annals of Oncology: Official Journal of the European Society for Medical Oncology 29(7): 1606
Graham, L.; Banda, K.; Torres, A.; Carver, B.S.; Chen, Y.; Pisano, K.; Shelkey, G.; Curley, T.; Scher, H.I.; Lotan, T.L.; Hsieh, A.C.; Rathkopf, D.E. 2018: A phase Ii study of the dual mTOR inhibitor MLN0128 in patients with metastatic castration resistant prostate cancer. Investigational new Drugs 36(3): 458-467
Yam, C.; Murthy, R.K.; Valero, V.; Szklaruk, J.; Shroff, G.S.; Stalzer, C.J.; Buzdar, A.U.; Murray, J.L.; Yang, W.; Hortobagyi, G.N.; Moulder, S.L.; Arun, B. 2018: A phase Ii study of tipifarnib and gemcitabine in metastatic breast cancer. Investigational new Drugs 36(2): 299-306
Hotta, K.; Aoe, K.; Kozuki, T.; Ohashi, K.; Ninomiya, K.; Ichihara, E.; Kubo, T.; Ninomiya, T.; Chikamori, K.; Harada, D.; Nogami, N.; Hirata, T.; Hinotsu, S.; Toyooka, S.; Kiura, K. 2018: A Phase Ii Study of Trastuzumab Emtansine in HER2-Positive Non-Small Cell Lung Cancer. Journal of Thoracic Oncology: Official Publication of the International Association for the Study of Lung Cancer 13(2): 273-279
Hirbe, A.C.; Jennings, J.; Saad, N.; Giardina, J.D.; Tao, Y.; Luo, J.; Berry, S.; Toeniskoetter, J.; Van Tine, B.A. 2018: A Phase Ii Study of Tumor Ablation in Patients with Metastatic Sarcoma Stable on Chemotherapy. Oncologist 23(7): 760-E76
López, L.; Vélez, I.án.; Asela, C.; Cruz, C.; Alves, F.; Robledo, S.; Arana, B. 2018: A phase Ii study to evaluate the safety and efficacy of topical 3% amphotericin B cream (Anfoleish) for the treatment of uncomplicated cutaneous leishmaniasis in Colombia. Plos Neglected Tropical Diseases 12(7): E0006653
Korzeniowski, M.A.; Crook, J.M.; Bowes, D.; Gaztañaga, M.; Ots, A.; Jazwal, J.; Rose, J.; Tétreault-Laflamme, A.; Pilote, L.; Halperin, R.; Kim, D.; Petrik, D.; Araujo, C.; Bachand, F. 2018: A Phase II trial of 8 weeks of degarelix for prostate volume reduction: Efficacy and hormonal recovery. BrachyTherapy 17(3): 530-536
Yazbeck, V.; Shafer, D.; Perkins, E.B.; Coppola, D.; Sokol, L.; Richards, K.L.; Shea, T.; Ruan, J.; Parekh, S.; Strair, R.; Flowers, C.; Morgan, D.; Kmieciak, M.; Bose, P.; Kimball, A.; Badros, A.Z.; Baz, R.; Lin, H.-Y.; Zhao, X.; Reich, R.R.; Tombes, M.B.; Shrader, E.; Sankala, H.; Roberts, J.D.; Sullivan, D.; Grant, S.; Holkova, B. 2018: A Phase Ii Trial of Bortezomib and Vorinostat in Mantle Cell Lymphoma and Diffuse Large B-cell Lymphoma. Clinical Lymphoma Myeloma and Leukemia 18(9): 569-575.E1
Nishikawa, K.; Tsuburaya, A.; Yoshikawa, T.; Takahashi, M.; Tanabe, K.; Yamaguchi, K.; Yoshino, S.; Namikawa, T.; Aoyama, T.; Rino, Y.; Kawada, J.; Tsuji, A.; Taira, K.; Kimura, Y.; Kodera, Y.; Hirashima, Y.; Yabusaki, H.; Hirabayashi, N.; Fujitani, K.; Miyashita, Y.; Morita, S.; Sakamoto, J. 2018: A phase Ii trial of capecitabine plus cisplatin (XP) for patients with advanced gastric cancer with early relapse after S-1 adjuvant therapy: XParTS-i trial. Gastric Cancer: Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 21(5): 811-818
Kuyama, S.; Ochi, N.; Bessho, A.; Hotta, K.; Ikeda, G.; Kishino, D.; Kubo, T.; Harada, D.; Fujimoto, N.; Nakanishi, M.; Umeno, T.; Okada, T.; Chikamori, K.; Yamagishi, T.; Ohashi, K.; Ichihara, E.; Takigawa, N.; Tanimoto, M.; Kiura, K. 2017: A phase Ii trial of carboplatin plus S-1 for elderly patients with advanced non-small-cell lung cancer with wild-type epidermal growth factor receptor: the Okayama Lung Cancer Study Group Trial 1202. Lung Cancer 112: 188-194
Xia, Y.; Li, Y.-H.; Chen, Y.; Liu, Q.; Zhang, J.-H.; Deng, J.-Y.; Ai, T.-S.; Zhu, H.-T.; Badakhshi, H.; Zhao, K.-L. 2018: A phase Ii trial of concurrent chemoradiotherapy with weekly paclitaxel and carboplatin in advanced oesophageal carcinoma. International Journal of Clinical Oncology 23(3): 458-465
Fujimoto, N.; Aoe, K.; Kozuki, T.; Oze, I.; Kato, K.; Kishimoto, T.; Hotta, K. 2018: A Phase Ii Trial of First-Line Combination Chemotherapy with Cisplatin, Pemetrexed, and Nivolumab for Unresectable Malignant Pleural Mesothelioma: a Study Protocol. Clinical Lung Cancer 19(5): E705-E707
Saito, K.; Isayama, H.; Sakamoto, Y.; Nakai, Y.; Ishigaki, K.; Tanaka, M.; Watadani, T.; Arita, J.; Takahara, N.; Mizuno, S.; Kogure, H.; Ijichi, H.; Tateishi, K.; Tada, M.; Hasegawa, K.; Fukayama, M.; Kokudo, N.; Koike, K. 2018: A phase Ii trial of gemcitabine, S-1 and LV combination (GSL) neoadjuvant chemotherapy for patients with borderline resectable and locally advanced pancreatic cancer. Medical Oncology 35(7): 100
Tanaka, I.; Kawada, K.; Morise, M.; Hase, T.; Hayashi, H.; Sokai, A.; Fukatsu, A.; Kondo, M.; Nomura, F.; Hasegawa, Y. 2018: A phase Ii trial of Ifosfamide combination with recommended supportive therapy for recurrent SCLC in second-line and heavily treated setting. Cancer ChemoTherapy and Pharmacology 81(2): 339-345
Nishio, S.; Shimokawa, M.; Tasaki, K.; Nasu, H.; Yoshimitsu, T.; Matsukuma, K.; Terada, A.; Tsuda, N.; Kawano, K.; Ushijima, K. 2018: A phase II trial of irinotecan in patients with advanced or recurrent endometrial cancer and correlation with biomarker analysis. Gynecologic Oncology 150(3): 432-437
Droller, M.J. 2000: A phase Ii trial of methotrexate, cisplatin, 5-fluorouracil, and leucovorin in the treatment of invasive and metastatic urothelial carcinoma. Journal of Urology 163(5): 1601
Mehnert, J.M.; Silk, A.W.; Lee, J.H.; Dudek, L.; Jeong, B.-S.; Li, J.; Schenkel, J.M.; Sadimin, E.; Kane, M.; Lin, H.; Shih, W.J.; Zloza, A.; Chen, S.; Goydos, J.S. 2018: A phase Ii trial of riluzole, an antagonist of metabotropic glutamate receptor 1 (GRM1) signaling, in patients with advanced melanoma. Pigment Cell and Melanoma Research 31(4): 534-540
Torka, P.; Patel, P.; Tan, W.; Wilding, G.; Bhat, S.A.; Czuczman, M.S.; Lee, K.P.; Deeb, G.; Neppalli, V.; Mavis, C.; Wallace, P.; Hernandez-Ilizaliturri, F.J. 2018: A Phase Ii Trial of Rituximab Combined with Pegfilgrastim in Patients with Indolent B-cell Non-Hodgkin Lymphoma. Clinical Lymphoma Myeloma and Leukemia 18(1): E51-E60
Lee, D.-W.; Lee, K.-H.; Kim, H.-J.; Kim, T.-Y.; Kim, J.-S.; Han, S.-W.; Oh, D.-Y.; Kim, J.H.; Im, S.-A.; Kim, T.-Y. 2018: A phase Ii trial of S-1 and oxaliplatin in patients with advanced hepatocellular carcinoma. Bmc Cancer 18(1): 252
Wei, X.X.; Siegel, A.P.; Aggarwal, R.; Lin, A.M.; Friedlander, T.W.; Fong, L.; Kim, W.; Louttit, M.; Chang, E.; Zhang, L.; Ryan, C.J. 2018: A Phase Ii Trial of Selinexor, an Oral Selective Inhibitor of Nuclear Export Compound, in Abiraterone- and/or Enzalutamide-Refractory Metastatic Castration-Resistant Prostate Cancer. Oncologist 23(6): 656-E64
D'Adamo, D.R.; Dickson, M.A.; Keohan, M.L.; Carvajal, R.D.; Hensley, M.L.; Hirst, C.M.; Ezeoke, M.O.; Ahn, L.; Qin, L.-X.; Antonescu, C.R.; Lefkowitz, R.A.; Maki, R.G.; Schwartz, G.K.; Tap, W.D. 2019: A Phase Ii Trial of Sorafenib and Dacarbazine for Leiomyosarcoma, Synovial Sarcoma, and Malignant Peripheral Nerve Sheath Tumors. Oncologist 24(6): 857-863
Park, Y.H.; Lee, K.-H.; Sohn, J.H.; Lee, K.S.; Jung, K.H.; Kim, J.-H.; Lee, K.H.; Ahn, J.S.; Kim, T.-Y.; Kim, G.M.; Park, I.H.; Kim, S.-B.; Kim, S.H.; Han, H.S.; Im, Y.-H.; Ahn, J.-H.; Kim, J.-Y.; Kang, J.; Im, S.-A. 2018: A phase Ii trial of the pan-HER inhibitor poziotinib, in patients with HER2-positive metastatic breast cancer who had received at least two prior HER2-directed regimens: results of the NOV120101-203 trial. International Journal of Cancer 143(12): 3240-3247
Munemoto, Y.; Kanda, M.; Oba, K.; Kim, H.M.; Takemoto, H.; Denda, T.; Nagata, N.; Takano, N.; Fukunaga, M.; Kataoka, M.; Tokunaga, Y.; Sakamoto, J.; Mishima, H. 2018: A phase Ii trial to evaluate the efficacy of panitumumab combined with fluorouracil-based chemotherapy for metastatic colorectal cancer: the PF trial. Cancer ChemoTherapy and Pharmacology 81(5): 829-838
Dinner, S.; Dunn, T.J.; Price, E.; Coutré, S.E.; Gotlib, J.; Berube, C.; Kaufman, G.P.; Medeiros, B.C.; Liedtke, M. 2018: A phase I, open-label, dose-escalation study of amrubicin in combination with lenalidomide and weekly dexamethasone in previously treated adults with relapsed or refractory multiple myeloma. International Journal of Hematology 108(3): 267-273
Li, Y.; Liu, L.; Huang, L.; Wang, X.; Hoffmann, M.; Reyes, J.; Palmisano, M.; Zhou, S. 2018: A Phase I, open-label, randomized, crossover study in healthy subjects to evaluate the bioavailability of, and the food effect on, a pomalidomide oral liquid suspension. Clinical Pharmacology: Advances and Applications 10: 89-99
Miyatake, D.; Nakada, N.; Takada, A.; Kato, K.; Taniuchi, Y.; Katashima, M.; Sawamoto, T. 2018: A phase I, open-label, single-dose micro tracer mass balance study of 14C-labeled ASP7991 in healthy Japanese male subjects using accelerator mass spectrometry. Drug Metabolism and Pharmacokinetics 33(2): 118-124
Hussein, J.; Zewdie, M.; Yamuah, L.; Bedru, A.; Abebe, M.; Dagnew, A.F.; Chanyalew, M.; Yohannes, A.G.; Ahmed, J.; Engers, H.; Doherty, T.M.; Bang, P.; Kromann, I.; Hoff, S.ør.T.; Aseffa, A. 2018: A phase I, open-label trial on the safety and immunogenicity of the adjuvanted tuberculosis subunit vaccine H1/IC31® in people living in a TB-endemic area. Trials 19(1): 24
Aghajanian, C.; Bell-McGuinn, K.M.; Burris, H.A.; Siu, L.L.; Stayner, L.-A.; Wheler, J.J.; Hong, D.S.; Kurkjian, C.; Pant, S.; Santiago-Walker, A.; Gauvin, J.L.; Antal, J.M.; Opalinska, J.B.; Morris, S.R.; Infante, J.R. 2018: A phase I, open-label, two-stage study to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of the oral AKT inhibitor GSK2141795 in patients with solid tumors. Investigational new Drugs 36(6): 1016-1025
Malik, L.; Zwiebel, A.; Cooper, J. 2018: A phase i pharmacokinetic and pharmacodynamic study of GTI-2040 in combination with gemcitabine in patients with solid tumors. Cancer ChemoTherapy and Pharmacology 82(3): 533-539
Leroux-Roels, G.; Lattanzi, M.; Solis, C.Dovali.; Contorni, M.; Costantini, M.; Moraschini, L.; Bardelli, M.; Bertholet, S.; Borgogni, E.; Buricchi, F.; Cantisani, R.; Faenzi, E.; Finco, O.; Leuzzi, R.; Pizza, M.; Rosa, D.; Schiavetti, F.; Seubert, A.; Spensieri, F.; Volpini, G.; Zedda, L.; Giudice, G.Del.; Galgani, I. 2018: A phase I, randomized, controlled, dose-ranging study of investigational acellular pertussis (aP) and reduced tetanus-diphtheria-acellular pertussis (TdaP) booster vaccines in adults. Human Vaccines and Immunotherapeutics 14(1): 45-58
Schaffler, K.; He, W.; Passier, P.; Tracy, K.; Fakhoury, A.; Paul, J. 2018: A Phase I, Randomized, Double-Blind, Laser-Evoked Potential Study to Evaluate the Analgesic/Antihyperalgesic Effect of ASP9226, a State-Dependent N-Type Voltage-Gated Calcium Channel Inhibitor, in Healthy Male Subjects. Pain Medicine 19(11): 2246-2255
Yen, C.-J.; Kim, T.-Y.; Feng, Y.-H.; Chao, Y.; Lin, D.-Y.; Ryoo, B.-Y.; Huang, D.C.-L.; Schnell, D.; Hocke, J.; Loembé, A.èn.-B.; Cheng, A.-L. 2018: A Phase I/Randomized Phase Ii Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of Nintedanib versus Sorafenib in Asian Patients with Advanced Hepatocellular Carcinoma. Liver Cancer 7(2): 165-178
Cheung, T.T.; Yan Chiu, J.W.; Yuen, M.F.; Ling Lam, K.S.; Yung Cheung, B.M.; Feng, H.-P.; Yeh, W.W.; Wang, J.; Li, W.; Zhao, X.M.; Wang, Z.; Mu, S. 2018: A Phase I, Single- and Multiple-dose Study to Evaluate the Pharmacokinetics of Elbasvir and Grazoprevir in Healthy Chinese Participants. Clinical Therapeutics 40(5): 719-732.E1
Tempfer, C.B.; Giger-Pabst, U.; Seebacher, V.; Petersen, M.; Dogan, A.; Rezniczek, G.ün.A. 2018: A phase I, single-arm, open-label, dose escalation study of intraperitoneal cisplatin and doxorubicin in patients with recurrent ovarian cancer and peritoneal carcinomatosis. Gynecologic Oncology 150(1): 23-30
Dennie, J.; Vandell, A.G.; Inoue, S.; Gajee, R.; Pav, J.; Zhang, G.; Zamora, C.; Masuda, N.; Uchiyama, M.; Yamada, M.; Senaldi, G. 2018: A Phase I, Single-Ascending-Dose Study in Healthy Subjects to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DS-2969b, a Novel GyrB Inhibitor. Journal of Clinical Pharmacology 58(12): 1557-1565
Yanagimoto, H.; Toyokawa, H.; Sakai, D.; Wada, H.; Satoi, S.; Yamamoto, T.; Nagano, H.; Toyoda, M.; Ajiki, T.; Satake, H.; Tsuji, A.; Miyamoto, A.; Tsujie, M.; Takemura, S.; Yanagihara, K.; Ioka, T. 2018: A phase I study for adjuvant chemotherapy of gemcitabine plus S-1 in patients with biliary tract cancer undergoing curative resection without major hepatectomy (KHBO1202). Cancer ChemoTherapy and Pharmacology 81(3): 461-468
Tanaka, H.; Taima, K.; Tanaka, Y.; Itoga, M.; Ishioka, Y.; Nakagawa, H.; Baba, K.; Hasegawa, Y.; Takanashi, S.; Tasaka, S. 2018: A phase i study of afatinib for patients aged 75 or older with advanced non-small cell lung cancer harboring EGFR mutations. Medical Oncology 35(3): 34
White, P.C.; Adhikari, S.; Grishman, E.K.; Sumpter, K.M. 2018: A phase i study of anti-inflammatory therapy with rilonacept in adolescents and adults with type 1 diabetes mellitus. Pediatric Diabetes 19(4): 788-793
Pardee, T.S.; Anderson, R.G.; Pladna, K.M.; Isom, S.; Ghiraldeli, L.P.; Miller, L.D.; Chou, J.W.; Jin, G.; Zhang, W.; Ellis, L.R.; Berenzon, D.; Howard, D.S.; Hurd, D.D.; Manuel, M.; Dralle, S.; Lyerly, S.; Powell, B.L. 2018: A Phase i Study of CPI-613 in Combination with High-Dose Cytarabine and Mitoxantrone for Relapsed or Refractory Acute Myeloid Leukemia. Clinical Cancer Research: An Official Journal of the American Association for Cancer Research 24(9): 2060-2073
Meehan, R.; Kummar, S.; Do, K.; O'Sullivan Coyne, G.; Juwara, L.; Zlott, J.; Rubinstein, L.; Doroshow, J.H.; Chen, A.P. 2018: A Phase i Study of Ganetespib and Ziv-Aflibercept in Patients with Advanced Carcinomas and Sarcomas. Oncologist 23(11): 1269-E125
Saitoh, J.-I.; Shirai, K.; Abe, T.; Kubo, N.; Ebara, T.; Ohno, T.; Minato, K.; Saito, R.; Yamada, M.; Nakano, T. 2018: A Phase i Study of Hypofractionated Carbon-ion Radiotherapy for Stage IIi Non-small Cell Lung Cancer. Anticancer Research 38(2): 885-891
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Wood, P.J.; Strong, R.; McArthur, G.A.; Michael, M.; Algar, E.; Muscat, A.; Rigby, L.; Ferguson, M.; Ashley, D.M. 2018: A phase i study of panobinostat in pediatric patients with refractory solid tumors, including CNS tumors. Cancer ChemoTherapy and Pharmacology 82(3): 493-503
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Yang, S-Hung.; Shao, Y-Yun.; Lin, C-Chi.; Kuo, S-Hsin.; Cheng, A-Lii.; Yeh, K-Huei. 2018: A Phase I Study of S-1-based Concurrent Chemoradiotherapy Followed by Gemcitabine and S-1 in Metastatic Pancreatic Adenocarcinoma. Anticancer Research 38(8): 4805-4812
Wang, A.Y.; Weiner, H.; Green, M.; Chang, H.; Fulton, N.; Larson, R.A.; Odenike, O.; Artz, A.S.; Bishop, M.R.; Godley, L.A.; Thirman, M.J.; Kosuri, S.; Churpek, J.E.; Curran, E.; Pettit, K.; Stock, W.; Liu, H. 2018: A phase i study of selinexor in combination with high-dose cytarabine and mitoxantrone for remission induction in patients with acute myeloid leukemia. Journal of Hematology and Oncology 11(1): 4
Allison, M.; Hale, C. 2018: A Phase i Study of the Pharmacokinetics and Pharmacodynamics of Intranasal Doxylamine in Subjects with Chronic Intermittent Sleep Impairment. Drugs in R&d 18(2): 129-136
Gurrell, R.; Duvvuri, S.; Sun, P.; DeMartinis, N. 2018: A Phase i Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Novel Dopamine D1 Receptor Partial Agonist, PF-06669571, in Subjects with Idiopathic Parkinson's Disease. Clinical Drug Investigation 38(6): 509-517
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Ninomiya, T.; Nogami, N.; Kozuki, T.; Harada, D.; Kubo, T.; Ohashi, K.; Kuyama, S.; Kudo, K.; Bessho, A.; Fukamatsu, N.; Fujimoto, N.; Aoe, K.; Shibayama, T.; Sugimoto, K.; Takigawa, N.; Hotta, K.; Kiura, K. 2018: A phase i trial of afatinib and bevacizumab in chemo-naïve patients with advanced non-small-cell lung cancer harboring EGFR mutations: Okayama Lung Cancer Study Group Trial 1404. Lung Cancer 115: 103-108
Lee, V.; Wang, J.; Zahurak, M.; Gootjes, E.; Verheul, H.M.; Parkinson, R.; Kerner, Z.; Sharma, A.; Rosner, G.; De Jesus-Acosta, A.; Laheru, D.; Le, D.T.; Oganesian, A.; Lilly, E.; Brown, T.; Jones, P.; Baylin, S.; Ahuja, N.; Azad, N. 2018: A Phase I Trial of a Guadecitabine (SGI-110) and Irinotecan in Metastatic Colorectal Cancer Patients Previously Exposed to Irinotecan. Clinical Cancer Research: An Official Journal of the American Association for Cancer Research 24(24): 6160-6167
El-Khoueiry, A.B.; O'Donnell, R.; Semrad, T.J.; Mack, P.; Blanchard, S.; Bahary, N.; Jiang, Y.; Yen, Y.; Wright, J.; Chen, H.; Lenz, H.-J.; Gandara, D.R. 2018: A phase i trial of escalating doses of cixutumumab (IMC-A12) and sorafenib in the treatment of advanced hepatocellular carcinoma. Cancer ChemoTherapy and Pharmacology 81(5): 957-963
Williams, B.A.; Law, A.D.; Routy, B.; denHollander, N.; Gupta, V.; Wang, X.-H.; Chaboureau, A.él.; Viswanathan, S.; Keating, A. 2017: A phase i trial of NK-92 cells for refractory hematological malignancies relapsing after autologous hematopoietic cell transplantation shows safety and evidence of efficacy. Oncotarget 8(51): 89256-89268
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Vlahovic, G.; Meadows, K.L.; Hatch, A.J.; Jia, J.; Nixon, A.B.; Uronis, H.E.; Morse, M.A.; Selim, M.A.; Crawford, J.; Riedel, R.F.; Zafar, S.Y.; Howard, L.A.; O'Neill, M.; Meadows, J.J.; Haley, S.T.; Arrowood, C.C.; Rushing, C.; Pang, H.; Hurwitz, H.I. 2018: A Phase i Trial of the IGF-1R Antibody Ganitumab (AMG 479) in Combination with Everolimus (RAD001) and Panitumumab in Patients with Advanced Cancer. Oncologist 23(7): 782-790
Liu, S.V.; Groshen, S.G.; Kelly, K.; Reckamp, K.L.; Belani, C.; Synold, T.W.; Goldkorn, A.; Gitlitz, B.J.; Cristea, M.C.; Gong, I.-Y.; Semrad, T.J.; Xu, Y.; Xu, T.; Koczywas, M.; Gandara, D.R.; Newman, E.M. 2018: A phase i trial of topotecan plus tivantinib in patients with advanced solid tumors. Cancer ChemoTherapy and Pharmacology 82(4): 723-732
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Frenck, R.W.; Baqar, S.; Alexander, W.; Dickey, M.; McNeal, M.; El-Khorazaty, J.; Baughman, H.; Hoeper, A.; Barnoy, S.; Suvarnapunya, A.E.; Kaminski, R.W.; Venkatesan, M.M. 2018: A Phase i trial to evaluate the safety and immunogenicity of WRSs2 and WRSs3; two live oral candidate vaccines against Shigella sonnei. Vaccine 36(32 Part B): 4880-4889
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