+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Cost-effective use of rapid diagnostic techniques in the treatment and prevention of viral respiratory infections

Cost-effective use of rapid diagnostic techniques in the treatment and prevention of viral respiratory infections

Pediatric Annals 34(1): 24-31

The most cost-effective current use of rapid respiratory virus diagnostics is through highly sensitive and specific molecular assays (mostly PCR-based) in the hospital setting or for chronically ill or immunocompromised outpatients. Specifically, this cost savings is the result of preventing hospitalization or decreasing length of hospitalization, decreasing unnecessary testing and procedures, directing specific therapy, and reducing unnecessary antibiotic use. Equally important is community surveillance by informing physicians rapidly what agents are in the community. Important ongoing issues regarding the cost-effective use of these assays include the cost of reagents or machinery, reimbursement for testing, the need for reliable commercial reagents, the need for open platforms that can respond to new "emerging" or "reemerging" agents, and the need for proficiency panels to share between laboratories. Rapid molecular diagnostic assays for the detection of respiratory viruses have moved into the mainstream of clinical testing. These assays already play important roles in select populations and clinical situations for critical patient management. In addition, there are numerous clinical scenarios where the use of these assays should have a positive cost/benefit ratio. Further work needs to be done to demonstrate this benefit to society. Further development of multiplex assays and decreasing the cost of testing will help improve the benefit of these assays to clinical care. Work is underway on large multiplex molecular assays with high sensitivity and specificity that will be able to be used in an outpatient setting both because of speed and low cost. The future holds great potential for physicians. who soon may be able to answer the age-old question, "Doc, what do I have?" with more than, "You probably have a virus."

(PDF 0-2 workdays service: $29.90)

Accession: 048675248

Download citation: RISBibTeXText

PMID: 15693213

Related references

Comparison of rapid diagnostic techniques for respiratory syncytial and influenza A virus respiratory infections in young children. Journal of Clinical Microbiology 31(9): 2286-2290, 1993

Rapid diagnostic methods for acute viral respiratory infections. Enfermedades Infecciosas Y Microbiologia Clinica 34(6): 329-330, 2016

Techniques used for the diagnostic of upper and lower respiratory tract viral infections. La Revue du Praticien 57(17): 1876-1882, 2007

Cost-effectiveness of rapid diagnosis of viral respiratory tract infections in pediatric patients. Journal of Clinical Microbiology 35(6): 1579-1581, 1997

Viral, mycoplasmal and chlamydial lower respiratory tract infections in Hong Kong: cost and diagnostic value of serology. British Journal of Biomedical Science 51(1): 9-13, 1994

Modern diagnostic preparations required for the rapid discovery and recognition of the pathogens of respiratory viral infections. Anon Probl Etiol , Diagnost , Profilakt I Kliniki Respiratorn Virusn (Problems Of The Etiology, Diagnosis, Prophylaxis, And Clinical Aspects Of Respiratory Viral Infections ) Leningrad, Ussr From Ref Zh Biol No 85-92, 1969

Rapid diagnostic techniques in the etiological diagnosis of lower respiratory tract infections in children. Journal of Communicable Diseases 20(3): 226-231, 1988

Rapid point of care diagnostic tests for viral and bacterial respiratory tract infections--needs, advances, and future prospects. Lancet. Infectious Diseases 14(11): 1123-1135, 2015

Cost-effective treatment of lower respiratory tract infections. Pharmacoeconomics 10(1): 36-58, 1996

Viral infections of the respiratory tract: prevention and treatment. International Journal of Antimicrobial Agents 4(1): 1-22, 1994

Prevention and treatment of respiratory viral infections in children. Delaware Medical Journal 43(11): 315-319, 1971

Viral infections of respiratory tract Their treatment and prevention. 1946

Viral infections of respiratory tract; their treatment and prevention. Journal of the American Medical Association 132(9): 487-493, 2014

Surveillance of respiratory viral infections by rapid immunofluorescence diagnosis, with emphasis on the epidemiological development of respiratory syncytial virus infections. Journal of Hygiene 94(3): 349-356, 1985

The Use Of Cycloferon For The Treatment And Prevention Of Influenza And Acute Respiratory Viral Infections. Klinicheskaia Meditsina 93(3): 57-63, 2015