EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Diagnostic value of 64-slice multi-detector row cardiac CTA in symptomatic patients



Diagnostic value of 64-slice multi-detector row cardiac CTA in symptomatic patients



European Radiology 17(3): 603-609



Cardiac multi-detector-row computed tomography (MDCT) angiography has shown high levels of sensitivity and especially negative predictive value regarding the diagnosis of coronary artery disease (CAD). This study was designed to determine the value of a 64-slice-MDCT scanner in comparison to invasive coronary angiography for the detection of CAD in a population of symptomatic patients. Fifty-one patients with suspected CAD underwent conventional coronary angiography and ECG-gated cardiac 64-slice-MDCT angiography with a rotation time of 330 ms, a collimation of 64x0.6 mm and a slice thickness of 0.75 mm. Blinded patient- and segment-based analysis was performed for the detection of stenoses >or=70% of the vessel lumen. 95% of all coronary segments were assessable by MDCT angiography. Patient-based (segment-based) analysis revealed a sensitivity of 97.8% (86.7%), specificity of 50% (95.2%), positive predictive value of 93.6% (75.2%) and negative predictive value of 75% (97.7%). Inter-rater agreement revealed a kappa-value of 0.558 (0.722). In this symptomatic patient group a 64-slice-MDCT scanner shows good agreement on a segment-based analysis but only moderate agreement on a patient-based analysis. The diagnostic accuracy of 64-slice-MDCT coronary angiography is negatively influenced by the high pre-test probability of this symptomatic patient collective.

(PDF emailed within 0-6 h: $19.90)

Accession: 048780078

Download citation: RISBibTeXText

PMID: 17008986

DOI: 10.1007/s00330-006-0429-5



Related references

Diagnostic accuracy of 320-slice multi-detector computed tomography in patients with coronary artery bypass grafts. European Heart Journal 34(Suppl 1): P5349-P5349, 2013

64 Slice multi-detector row cardiac CT. Emergency Radiology 16(1): 1-10, 2008

Diagnostic accuracy of low-dose 256-slice multi-detector coronary CT angiography using iterative reconstruction in patients with suspected coronary artery disease. European Radiology 24(1): 3-11, 2014

Diagnostic Accuracy of a 64-Slice Multi-Detector CT Scan in the Preoperative Evaluation of Periampullary Neoplasms. Journal of Clinical Medicine 7(5): -, 2018

Limited diagnostic yield of non-invasive coronary angiography by 16-slice multi-detector spiral computed tomography in routine patients referred for evaluation of coronary artery disease. European Heart Journal 26(19): 1987-1992, 2005

Diagnostic evaluation of the craniocervical vascular system with a 16-slice multi-detector row spiral CT. Protocols and first experiences. Der Radiologe 42(9): 728-732, 2002

Diagnostic value of cardiac multi-detector computed tomography for detection of subclinical atherosclerosis in asymptomatic diabetic patients. European Heart Journal 34(Suppl 1): P5332-P5332, 2013

Incidental non-cardiac findings of a coronary angiography with a 128-slice multi-detector CT scanner: should we only concentrate on the heart?. Korean Journal of Radiology 11(1): 60-68, 2010

Assessment of left atrial volume and function in patients with permanent atrial fibrillation: comparison of cardiac magnetic resonance imaging, 320-slice multi-detector computed tomography, and transthoracic echocardiography. European Heart Journal Cardiovascular Imaging 15(5): 532-540, 2014

Analysis of cardiac dimensions, mass and function in heart transplant recipients using 64-slice multi-detector computed tomography. Journal of Heart and Lung Transplantation 26(5): 478-484, 2007

Diagnostic techniques for multi-slice cardiac CT. Nihon Hoshasen Gijutsu Gakkai Zasshi 62(6): 804-810, 2006

Utility of 320-slice multi-detector computed tomography for the diagnosis and evaluation of cardiac structures in a patient with a double-chambered right ventricle. Circulation Journal 75(11): 2711-2713, 2012

Performance evaluation of a multi-slice CT system with 16-slice detector and increased gantry rotation speed for isotropic submillimeter imaging of the heart. Herz 28(1): 7-19, 2003

Cochlear Implant Electrode Localization Using an Ultra-High Resolution Scan Mode on Conventional 64-Slice and New Generation 192-Slice Multi-Detector Computed Tomography. Otology & Neurotology 38(7): 978-984, 2017

Noninvasive imaging of cardiac venous anatomy with 64-slice multi-slice computed tomography and noninvasive assessment of left ventricular dyssynchrony by 3-dimensional tissue synchronization imaging in patients with heart failure scheduled for cardiac resynchronization therapy. American Journal of Cardiology 101(7): 1023-1029, 2008