+ Most Popular
Cunninghamia lanceolata plantations in China
Mammalian lairs in paleo ecological studies and palynology
Studies on technological possibilities in utilization of anhydrous milk fat for production of recombined butter-like products
Should right-sided fibroelastomas be operated upon?
Large esophageal lipoma
Apoptosis in the mammalian thymus during normal histogenesis and under various in vitro and in vivo experimental conditions
Poissons characoides nouveaux ou non signales de l'Ilha do Bananal, Bresil
Desensitizing efficacy of Colgate Sensitive Maximum Strength and Fresh Mint Sensodyne dentifrices
Administration of fluid by subcutaneous infusion: revival of a forgotten method
Tundra mosquito control - an impossible dream?
Schizophrenia for primary care providers: how to contribute to the care of a vulnerable patient population
Geochemical pattern analysis; method of describing the Southeastern limestone regional aquifer system
Incidence of low birth weights in a hospital of Mexico City
Graded management intensity of grassland systems for enhancing floristic diversity
Microbiology and biochemistry of cheese and fermented milk
The ember tetra: a new pygmy characid tetra from the Rio das Mortes, Brazil, Hyphessobrycon amandae sp. n. (Pisces, Characoidei)
Risk factors of contrast-induced nephropathy in patients after coronary artery intervention
Renovation of onsite domestic wastewater in a poorly drained soil
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Systolic blood pressure in a population of infants in the first year of life: the Brompton study
Haematological studies in rats fed with metanil yellow
Studies on pasteurellosis. I. A new species of Pasteurella encountered in chronic fowl cholera
Dormancy breaking and germination of Acacia salicina Lindl. seeds
therapy of lupus nephritis. a two-year prospective study

Effects of human milk fortification on morbidity factors in very low birth weights infants

Effects of human milk fortification on morbidity factors in very low birth weights infants

Annals of Saudi Medicine 21(5-6): 292-295

ISSN/ISBN: 0256-4947

PMID: 17261931

The use of human milk as a sole source of nutrients for preterm infants has been the subject of debate in recent years. We studied the morbidity factors associated with hospitalization of very low birth weight (VLBW) infants fed human milk with and without fortification. One hundred VLBW infants were randomly assigned to two groups with stratification for gestation and weight. The control group (n=50; mean birth weight 1239+/-186 g and mean gestation 29.3+/-2.1 wks) was fed human milk only, and in the fortifier group (n=50; mean birth weight 1245+/-191 g and mean gestation 29.5+/-2.1 wks), human milk was enriched with a fortifier after the babies reached a volume of 140 mL/kg/day by the enteral route. Weight was measured twice weekly, biochemical indices of nutritional and bone status and serum electrolytes were obtained weekly, and clinical evidence for sepsis, necrotizing enterocolitis and feeding intolerance was assessed regularly until infants were discharged. Hospital stay was less than 45 days in the majority (94%) of the babies in the fortifier group, whereas the majority (66%) of the babies in the control group stayed for more than 45 days (P<0.01). Low serum phosphorus and raised alkaline phosphatase levels were seen more frequently in the control group without fortification (P<0.01), as well as hyponatremia (P<0.01), late metabolic acidosis of prematurity (P<0.01) and culture-proven sepsis (P<0.05). There was no significant difference in the occurrence of necrotizing enterocolitis between the two groups (P>0.05). Human milk fortification has beneficial effects on the growth of VLBW infants and decreases hospital stay and morbidity associated with prematurity and very low birth weight, with economic and psychological benefits for the parents.

Please choose payment method:

(PDF emailed within 1 workday: $29.90)

Accession: 048909011

Download citation: RISBibTeXText

Related references

Effects of human milk fortification on morbidity factors in very low birth weight infants. Annals of Saudi Medicine 23(1-2): 28-31, 2003

Effects of human milk fortification on morbidity factors in very low birth weight infants. Annals of Saudi Medicine 21(5/6): 292-295, 2001

Randomized trial of human milk cream as a supplement to standard fortification of an exclusive human milk-based diet in infants 750-1250 g birth weight. Journal of Pediatrics 165(5): 915-920, 2014

Individualized fortification of human milk for very low birth weight infants Milk protein and energy analyses for improved nutritional management. Pediatric Research 37(4 Part 2): 316A, 1994

Safety and efficacy of human milk fortification for very-low-birth-weight infants. Nutrition reviews 62(12): 482-489, 2004

Additional Protein Fortification Is Necessary in Extremely Low-Birth-Weight Infants Fed Human Milk. Journal of Pediatric Gastroenterology and Nutrition 63(1): 103-105, 2016

Variability in human milk composition: benefit of individualized fortification in very-low-birth-weight infants. American Journal of Clinical Nutrition 98(2): 529s-535s, 2013

Fortification of human milk in very low birth weight infants (VLBW <1500 g birth weight). Clinics in Perinatology 41(2): 405-421, 2014

Early versus Delayed Human Milk Fortification in Very Low Birth Weight Infants-A Randomized Controlled Trial. Journal of Pediatrics 174: 126-131.E1, 2016

The plasma phenylalanine level in newborn infants of normal and low birth weights fed on human milk. Biologia Neonatorum. Neo-Natal Studies 13(5): 315-324, 1968

The plasma phenylalanine level in newborn infants of normal and low birth weights fed on human milk. Biol. Neonat 13: 315-324, 1969

Simple and rapid macronutrient analysis of human milk for individualized fortification: basis for improved nutritional management of very-low-birth-weight infants?. Journal of Pediatric Gastroenterology and Nutrition 17(3): 283-290, 1993

Post Discharge Formula Fortification of Maternal Human Milk of Very Low Birth Weight Preterm Infants: An Introduction of a Feeding Protocol in a University Hospital. Pediatric reports 8(3): 6632, 2016

Morbidity and mortality among infants with birth weights of 1000 grams or less. Pediatric Research 16(4 Part 2): 289A, 1982

Interdisciplinary assessment of morbidity of infants with birth weights 950 grams. Pediatric Research 12(4 Part 2): 374, 1978