+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Evaluation of TNF-alpha, IL-8 and IL-10 transcriptional activity in milk from healthy dairy cows during lactation period

Evaluation of TNF-alpha, IL-8 and IL-10 transcriptional activity in milk from healthy dairy cows during lactation period

Veterinary Research Communications 29(Suppl. 2): 281-284

This study was conducted to measure the levels of normal transcriptional activity of 3 important cytokines (tumour necrosis factor alpha , interleukin 8 and interleukin 10) in milk from healthy cows and to determine the lactation stage-dependent changes in levels of these mediators. 50 second- and third-lactation healthy cows were grouped according to 3 different stages during the lactation cycle: early lactation (n=12); midlactation (n=18) and late lactation (n=20). Samples from early and late lactation periods tended to express lower levels of TNF- alpha and IL-8 than those from midlactation period. The IL-10 expression level in samples from early- and late-lactation tended to be higher than those from midlactation. The levels of cytokines in the 3 lactation groups were insignificantly different. Results showed that there were significant differences in the total profile of the 3 cytokines over the different lactation periods. Significant correlations both between IL-8 and IL-10 in midlactation period and among the 3 cytokines during late-lactation were observed. Cytokine transcription levels were more correlated in the late-lactation as compared with early- and midlactation periods.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 048993131

Download citation: RISBibTeXText

PMID: 16244975

DOI: 10.1007/s11259-005-0062-9

Related references

Evaluation of Acute Phase Proteins in Clinically Healthy Dairy Cows in Perinatal Period and During Lactation. Polish Journal of Veterinary Sciences 19(3): 519-523, 2016

Effects of milk production, season, parity and lactation period on variations of milk urea nitrogen concentration and milk components of Holstein dairy cows. Asian Australasian Journal of Animal Sciences 17(4): 479-484, 2004

Activities of AST, ALT and GGT in clinically healthy dairy cows during lactation and in the dry period. Veterinarski Arhiv 75(1): 67-73, 2005

Phagocytic phenomena in the mammary gland of cows. IV. Ratio of milk and serum opsonophagocytic indices in healthy cows during the first lactation period. Bulletin of the Veterinary Institute in Pulawy 16(3/4): 108-110, 1972

Effects of length of dry period on yields of milk fat and protein, fertility and milk somatic cell score in the subsequent lactation of dairy cows. Journal of Dairy Research 73(2): 154-162, 2006

Effects of feeding conjugated linoleic acids to dairy cows during the transition period and early lactation upon milk and milk component yields. Proceedings Of The Society Of Nutrition Physiology: 64, 2008

Changes in the composition of milk from healthy and mastitic dairy cows during the lactation cycle. Australian Journal of Experimental Agriculture 35(4): 427-436, 1995

Milk production of dairy cows fed wet corn gluten feed during the dry period and lactation. Journal of Dairy Science 89(7): 2608-2617, 2006

Oxytetracycline in the milk of dairy cows with clinical signs of mastitis during the lactation period. Veterinarni Medicina 41(11): 329-333, 1996

Milk production of dairy cows injected with low dose of bovine somatotropin during the transition period and lactation. Journal of Dairy Science 86(Suppl. 1): 296, 2003

Influence of lactation stage, milk fat and age of dairy cows on feed-related evaluation of data from milk recording. Tierarztliche Umschau 51(2): 84-88, 93-95, 1996

Changes in milk proteome and metabolome associated with dry period length, energy balance, and lactation stage in postparturient dairy cows. Journal of Proteome Research 12(7): 3288-3296, 2013

Influence of feeding on dairy cows on the milk composition. I. changes of milk composition during the period of lactation. 1974