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Evaluation of body weight as a predictive factor for transvenous ventricular defibrillation characteristics

Evaluation of body weight as a predictive factor for transvenous ventricular defibrillation characteristics

Europace 6(1): 21-24

To investigate the correlation between body weight and defibrillation threshold (DFT) for transvenous lead systems using a porcine model. Twenty-eight pigs were anaesthetised and DFTs assessed in single and dual coil configurations using a four-reversal binary search method. DFT was correlated with body weight in the RV --> Can and RV --> SVC + Can configurations. A Pearson correlation coefficient and a two-sided p-value were calculated. A positive correlation exists between body weight and DFT in RV --> Can (r=0.66, p<0.000) and RV --> SVC + Can (r=0.44, p=0.018). There is a significant correlation between body weight and DFT in swine. This tends to be greater in the two-electrode than in the three-electrode configuration. With these and previous human observations, one may predict a higher DFT in heavy individuals and make appropriate procedural adjustments.

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Accession: 048994963

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PMID: 14697722

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