+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Expression of the mouse FGF-1 and FGF-1.A mRNAs during embryonic development and in the aging heart

Expression of the mouse FGF-1 and FGF-1.A mRNAs during embryonic development and in the aging heart

Research Communications in Molecular Pathology and Pharmacology 112(1-4): 139-144

The mouse Fgf-1 gene contains at least four upstream promoters that are alternatively spliced to the first protein coding exon, giving rise to different Fgf-1 mRNA variants (1.A, 1.B, 1.C, and 1.G), each expressed in a tissue specific manner. Only the Fgf-1.A promoter contains TATA and CAAT consensus sequences, and its corresponding mRNA is mainly expressed in the mouse heart. In situ hybridization with an Fgf-1.A-specific cRNA probe showed the 1.A message to be very low in embryonic heart, tongue, spinal cord and smooth muscle of the small intestine. Moderate 1.A mRNA levels were revealed in head mesenchyme, paraxial mesoderm, in the embryonic inferior cunniculus, hyppocampus, and thymus. These results suggest a limited role of the Fgf-1.A mRNA variant during development.

Please choose payment method:

(PDF emailed within 1 workday: $29.90)

Accession: 049045264

Download citation: RISBibTeXText

PMID: 15080504

Related references

Histological development and dynamic expression of Bmp2-6 mRNAs in the embryonic and postnatal mouse cranial base. Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology 288(12): 1250-1258, 2006

Differential expression of muscarinic receptor mRNAs and their subtypes during development of embryonic chick heart and retina. Life Sciences 56(11-12): 1023, 1995

Differential expression of muscarinic acetylcholine receptor mRNAs and their subtypes during development of embryonic chick heart and retina. Society for Neuroscience Abstracts 19(1-3): 1338, 1993

Cloning and characterization of a novel form of mouse fibroblast growth factor-1 (FGF-1) mRNA, FGF-1.G: differential expression of FGF-1 and FGF-1.G mRNAs during embryonic development and in postnatal tissues. Biochimica et Biophysica Acta, Gene Structure and Expression 1521(1/3): 45-58, 2001

Nicotine stimulates branching and expression of SP-A and SP-C mRNAs in embryonic mouse lung culture. American Journal of Physiology 274(1): L165-L170, 1998

Expression of the beta 4 integrin subunit in the mouse heart during embryonic development: retinoic acid advances beta 4 expression. Developmental Dynamics 207(1): 89, 1996

Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development. Proceedings of the National Academy of Sciences of the United States of America 106(17): 7028-7033, 2009

Embryonic and postnatal expression of four gamma-aminobutyric acid transporter mRNAs in the mouse brain and leptomeninges. Journal Of Comparative Neurology. 376(3): 431-446, 1996

Changes in state of adenylation and time course of degradation of maternal mRNAs during oocyte maturation and early embryonic development in the mouse. Developmental Biology 129(2): 304-314, 1988

Embryonic expression of neurotrophic Trk receptor mRNAs within sensory neurons Chicken development as a model. Ibanez, C F , Hoekfelt, T , Fuxe, K , Joernvall, H , Ottoson, D Wenner-Gren International Series, Vol 67; Life and death in the nervous system: Role of neurotrophic factors and their receptors 113-130, 1995

DNA methyltransferase expression in embryonic and extra-embryonic tissues during post-implantation mouse development. Biology of Reproduction 50(Suppl. 1): 154, 1994

Effect of antioxidant of bamboo leaves on gene expression associated with mouse embryonic fibroblast reproduction and embryonic development. Molecular Medicine Reports 16(5): 7490-7496, 2017

Stem-loop binding protein expressed in growing oocytes is required for accumulation of mRNAs encoding histones H3 and H4 and for early embryonic development in the mouse. Developmental Biology 313(1): 347-358, 2008

The expression of the imprinted gene Ipl is restricted to extra-embryonic tissues and embryonic lateral mesoderm during early mouse development. International Journal of Developmental Biology 46(4): 459-466, 2002

Differential expression of Isk mRNAs in mouse tissue during development and pregnancy. American Journal of Physiology 267(3 Pt 1): C700-C705, 1994