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Genetic comparison of large fragment of the 5'untranslated region among foot-and-mouth disease viruses with special reference to serotype Asia1

, : Genetic comparison of large fragment of the 5'untranslated region among foot-and-mouth disease viruses with special reference to serotype Asia1. Archives of Virology 150(11): 2217-2239

Foot-and-mouth disease (FMD), the most economically important disease of cloven-hoofed animals, is endemic in India. Sequence analysis revealed that phylogenetic grouping of type Asia1 field isolates on the basis of the large fragment of the 5'untranslated region (5'LF-UTR) was quite similar to that based on the sequences of the capsid-coding (VP1) region of the same viruses. The existence of two distinct lineages of type Asia1 suggested by the study on the VP1 region was further supported by the detection of a difference in length and predicted secondary structure of the 5'LF-UTR between the two lineages. Sequence variability between the isolates of the two lineages was also observed within the different domains of the internal ribosome entry site (IRES) around conserved motifs like the GNRA,- RAAA,- and the polypyrimidine tract. Certain group and lineage-specific signature nucleotides pertaining to FMDV type Asia1 in the 5'LF-UTR have been identified. The present study shows that the 5'LF-UTR of FMDV serotype Asia1 field isolates are variable in relation to the length and probable secondary structure of the IRES.

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Accession: 049149305

PMID: 15968474

DOI: 10.1007/s00705-005-0576-z

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Bongioanni, M.; Perazzo, E., 1967: Changes in tissue oncotic capacity in acute hepatic and adrenal insufficiency. Archivio Per le Scienze Mediche 123(1): 33-41

Frederick J.E., 1989: Spatial and temporal variations in uv radiation at the earths surface. Photochemistry & Photobiology 49(SUPPL): 66S

Anonymous, 1978: Nurse's role in psychiatric services. Soins; la Revue de Reference Infirmiere 23(8): 39-55

Musil, V., 1977: How much heating oil does a flue gas valve save daily?. Champignon 189 20-21

Hornnes, P.J., 1999: Cesarean section--who makes the decision?. Ugeskrift for Laeger 161(40): 5517-5517

Gardos, G., 1984: Undiagnosed dystonic reaction secondary to amoxapine. Psychosomatics 25(1): 66, 69-66, 69

Hecht, S.T., 1993: Failure-avoidance analysis: a brief introduction for neuroradiologists. Ajnr. American Journal of Neuroradiology 14(5): 1094-1096

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Comar, C.L.; Nelson, N., 1975: Health effects of fossil fuel combustion products: report of a workshop. Judgemental positions are presented on research priorities in regard to the health effects from stationary sources of fossil fuel combustion products. Hopefully, they can provide guidance for efforts to ensure that national energy needs are met wi...

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