Initial comfort of lotrafilcon a silicone hydrogel contact lenses versus etafilcon a contact lenses for extended wear

Martin, R.; de Juan, V.; Rodriguez, G.; Martin, S.; Fonseca, S.

Contact Lens and Anterior Eye the Journal of the British Contact Lens Association 30(1): 23-28

2007


ISSN/ISBN: 1367-0484
PMID: 17178252
DOI: 10.1016/j.clae.2006.11.002
Accession: 049361315

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Abstract
To compare the initial comfort afforded by silicone hydrogel lenses (lotrafilcon A) versus the comfort afforded by conventional hydrogel lenses (etafilcon A) in extended wear (EW). Prospective, double-masked and randomized controlled trial. Lotrafilcon A and etafilcon A contact lenses were eye randomly fitted on an EW basis for 7 days and nights in 20 subjects. A forced-choice subject preference questionnaire was made. Subjects were comfort, dryness, red eye and visual quality after night wear and at the end of the day. Subjective scored satisfaction (scale: 1-5) and lens preference were assessed. Lotrafilcon A proved more comfortable after night wear (60%, CI95% 38-82%) and at the end of the day (70%, CI95% 49-90%) than etafilcon A after night wear (10%, CI95% 0-23%, P<0.05) and at the end of the day (20%, CI95% 2-38%, P<0.05). The feeling of dryness was more marked with etafilcon A after night wear (50%, CI95% 27-72%) and at the end of the day (50%, CI95% 27-72%) than it was with lotrafilcon A (15%, CI95% 0%-31%) after night wear (P>0.05) and at the end of the day (25%, CI95% 5%-44%, P<0.05). General satisfaction with the lotrafilcon A lens was 3.65 points (CI95% 3-4.2) and with etafilcon A 2.95 points (CI95% 2.5-3.3, P<0.05). Eighty percent (CI95% 62%-98%) of subjects preferred lotrafilcon A (P<0.05) for EW. In EW, lotrafilcon A contact lenses were more comfortable and led to less dryness after night wear and at the end of the day than etafilcon A contact lenses.