+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Introduction of single mutation changes arylmalonate decarboxylase to racemase



Introduction of single mutation changes arylmalonate decarboxylase to racemase



Chemical Communications: 3600-3602



The introduction of only one mutation based on the estimated reaction mechanism endowed arylmalonate decarboxylase with a racemase activity, which catalyses racemisation of alpha-arylpropionates.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 049399446

Download citation: RISBibTeXText

PMID: 17047777

DOI: 10.1039/b607211a


Related references

Engineering the promiscuous racemase activity of an arylmalonate decarboxylase. Chemistry 17(2): 557-563, 2011

Inversion of enantioselectivity of arylmalonate decarboxylase by point mutation. Journal of Molecular Catalysis B Enzymatic 18(1-3): 177-178, 13 September, 2002

Promiscuity of arylmalonate decarboxylase. 2007

Studies on the function of arylmalonate decarboxylase. Journal of Molecular Catalysis B Enzymatic 14(1-3): 60, 12 June, 2001

Purification and characterization of arylmalonate decarboxylase from Achromobacter sp. KU1311. Journal of Bioscience and Bioengineering 104(4): 263-267, 2007

Improvement of the activity of arylmalonate decarboxylase by random mutagenesis. Applied Microbiology and Biotechnology 73(3): 647-653, 2006

Purification and properties of a novel arylmalonate decarboxylase from Alcaligenes bronchisepticus KU 1201. European Journal of Biochemistry 210(2): 475-481, 1992

Arylmalonate decarboxylase-a highly selective bacterial biocatalyst with unknown function. Applied Microbiology and Biotechnology 100(20): 8621-8631, 2016

Crystallization and preliminary X-ray diffraction experiments of arylmalonate decarboxylase from Alcaligenes bronchisepticus. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications 64(Pt 7): 610-613, 2008

Cloning and heterologous expression of a novel arylmalonate decarboxylase gene from Alcaligenes bronchisepticus KU 1201. Applied Microbiology & Biotechnology. 38(2): 234-238, 1992

Conversion of a PLP-dependent racemase into an aldolase by a single active site mutation. Journal of the American Chemical Society 125(34): 10158-9, 2003

Active-site mobility revealed by the crystal structure of arylmalonate decarboxylase from Bordetella bronchiseptica. Journal of Molecular Biology 377(2): 386-394, 2008

Asymmetric decarboxylation of Î -hydroxy- and Î -amino-Î -phenylmalonate catalyzed by arylmalonate decarboxylase from Alcaligenes bronchisepticus. 2008