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Modulated microRNA expression during adult lifespan in Caenorhabditis elegans



Modulated microRNA expression during adult lifespan in Caenorhabditis elegans



Aging Cell 5(3): 235-246



MicroRNAs (miRNAs) are small, abundant transcripts that can bind partially homologous target messages to inhibit their translation in animal cells. miRNAs have been shown to affect a broad spectrum of biological activities, including developmental fate determination, cell signaling and oncogenesis. Little is known, however, of miRNA contributions to aging. We examined the expression of 114 identified Caenorhabditis elegans miRNAs during the adult lifespan and find that 34 miRNAs exhibit changes in expression during adulthood (P

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Accession: 049612165

Download citation: RISBibTeXText

PMID: 16842496

DOI: 10.1111/j.1474-9726.2006.00210.x


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