+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Nasal cytology: description of a hyperchromatic supranuclear stria as a possible marker for the anatomical and functional integrity of the ciliated cell



Nasal cytology: description of a hyperchromatic supranuclear stria as a possible marker for the anatomical and functional integrity of the ciliated cell



American Journal of Rhinology 17(5): 263-268



The aim of this study was to describe a particular intracellular hyperchromatic formation located over the nucleus of normal nasal ciliated cells. This finding, never described in literature, very rarely occurs in pathological conditions. A nasal cytological test and mucociliary transport test were performed in a group of 24 subjects with rhinologic diseases and in a control group of 10 healthy subjects. The "hyperchromatic supranuclear stria" (SNS) was observed in a high percentage of normal cells (90.3%); SNS was present in very few pathological subjects (in only 6.26% of pathologic cells). We interpreted SNS as a specific marker for the anatomic and functional integrity of the ciliated cell. Therefore, the absence of SNS is considered an abnormal finding in the nasal mucosa and therefore could be useful as a "prognostic sign" of the disorders themselves and as an indication of the "therapeutic efficacy" of pharmacologic treatments, both topical and systemic.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 049657159

Download citation: RISBibTeXText

PMID: 14599129

DOI: 10.1177/194589240301700503


Related references

Nasal cytobrush cytology: evaluation of the hyperchromatic supranuclear stria. Acta Cytologica 50(4): 430-434, 2006

Supranuclear stria of ciliated cells in allergic rhinitis. Medicina 67(4): 360-362, 2007

MUC8 as a ciliated cell marker in human nasal epithelium. Acta Oto-Laryngologica 125(1): 76-81, 2005

Hyperchromatic crowded cell groups in gynaecological liquid-based cytology samples. British Journal of Biomedical Science 67(3): 154-63; Quiz 165, 2010

Image analysis of hyperchromatic crowded cell groups in SurePath cervical cytology. Cytopathology 24(2): 113-122, 2013

Number and distribution of small, hyperchromatic nuclei in ductal cell clusters in aspiration cytology of the breast. Acta Cytologica 42(2 Suppl. ): 549, March-April, 1998

Intravital functional study of ciliated epithelium cell in diseases of the nasal cavity and paranasal sinuses. Vestnik Otorinolaringologii (6): 55-58, 1987

Functional and anatomical integrity of adrenal cortices not dependent upon the structural integrity of the hypothalamus and midbrain. FED PROC 19(1 Pt 1): 152, 1960

Hyperchromatic crowded groups in cervical cytology--differing appearances and interpretations in conventional and ThinPrep preparations: a study from the College of American Pathologists Interlaboratory Comparison Program in Cervicovaginal Cytology. Archives of Pathology & Laboratory Medicine 130(3): 332-336, 2006

Evaluation of Anatomical Integrity Using Ultrasound Examination, and Functional Integrity Using the Constant & Murley Score, of the Rotator Cuff Following Arthroscopic Repair. Revista Brasileira de Ortopedia 45(2): 174-180, 2010

Nasal cytology: a marker of clinically silent inflammation in patients with obstructive sleep apnea and a predictor of noncompliance with nasal CPAP therapy. Journal of Clinical Sleep Medicine 1(3): 266-270, 2005

Ciliated cell adenocarcinoma of the endometrium diagnosed by endometrial brush cytology and confirmed by hysterectomy: A case report detailing a highly efficient cytology collection and processing technique. Diagnostic Cytopathology 16(1): 78-82, 1997

Anatomical and functional integrity of adrenal cortices not dependent on structural integrity of ventral hypothalamus; retention of eosinopenic response to surgery after ventral hypothalamectomy in the dog. American Journal of Physiology 179(1): 5-14, 1954

Functional activity of ciliated outgrowths from cultured human nasal and tracheal epithelia. Biorheology 27(3-4): 559-565, 1990