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Obstructive sleep apnea and head and neck neoplasms



Obstructive sleep apnea and head and neck neoplasms



Otolaryngology--Head and Neck Surgery 132(5): 794-799



To elaborate the relationship between obstructive sleep apnea (OSA) and head and neck neoplasms (HNN). A systematic review of the MEDLINE literature. Thirty of 34 articles indexed under OSA and HNN were about neoplasms that presented first as OSA. Four of the articles were about treatment of HNN causing OSA and gave incidences varying from 8% to 92%. Quality of life surveys confirm that patients with malignant HNN have sleep problems. Xerostomia may contribute to these sleep problems, and the role of salivary mucins deserves consideration. This review of the literature raises several new research questions about the clinical and biological relationships between OSA and HNN.

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Accession: 049738113

Download citation: RISBibTeXText

PMID: 15886637

DOI: 10.1016/j.otohns.2004.12.002


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