+ Site Statistics
References:
52,654,530
Abstracts:
29,560,856
PMIDs:
28,072,755
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Oxymorphone: a review



Oxymorphone: a review



Supportive Care in Cancer 14(2): 109-115



Oxymorphone (oxymorphone hydrochloride) (14-hydroxy-dihydromorphinone), a semisynthetic mu-opioid agonist, was first approved by the US Food and Drug Administration in 1959. Oxymorphone is considered a more potent opioid than its parent compound, morphine. Recently, an immediate-release and long-acting oral formulation of this drug was developed that makes oxymorphone a new option in treating moderate to severe pain. This article reviews the pharmacodynamics, pharmacology, and clinical efficacy for this new option in treating moderate to severe pain.

(PDF emailed within 0-6 h: $19.90)

Accession: 049839275

Download citation: RISBibTeXText

PMID: 16317569

DOI: 10.1007/s00520-005-0917-1


Related references

Oxymorphone and oxymorphone extended release: a pharmacotherapeutic review. Journal of Opioid Management 4(3): 131-144, 2008

Cardiovascular effects of epidurally administered oxymorphone and an oxymorphone-bupivacaine combination in halothane-anesthetized dogs. American Journal of Veterinary Research 60(2): 194-200, 1999

End tidal halothane concentration and postoperative analgesia requirements in dogs: a comparison between intravenous oxymorphone and epidural bupivacaine alone and in combination with oxymorphone. Canadian Veterinary Journal 39(6): 361-369, 1998

Simultaneous determination of oxymorphone and its active metabolite 6-OH-oxymorphone in human plasma by high performance liquid chromatography-tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences 902: 116-121, 2012

Comparisons of the analgesic effects of oral and intramuscular oxymorphone and of intramuscular oxymorphone and morphine in patients with cancer. Journal of Clinical Pharmacology 17(4): 186-198, 1977

Evaluation of the analgesic properties of acepromazine maleate, oxymorphone, medetomidine and a combination of acepromazine-oxymorphone. Veterinary Anaesthesia and Analgesia 27(2): 89-96, 2000

Review of oral oxymorphone in the management of pain. Therapeutics and Clinical Risk Management 4(4): 777-787, 2009

Ketorolac, Oxymorphone, Tapentadol, and Tramadol: A Comprehensive Review. Anesthesiology Clinics 35(2): E1-E20, 2017

A systematic review of oxymorphone in the management of chronic pain. Journal of Pain and Symptom Management 39(2): 296-308, 2010

Oxymorphone Extended-Release Tablets (Opana ER) For the Management of Chronic Pain: A Practical Review for Pharmacists. P and T 35(6): 324-357, 2010

A review of Oxymorphone hydrochloride analgesia employed for general surgery; including clinical experience with five hundred and twenty-eight patients. Cleveland Clin Quart 28(4): 262-269, 1961

A review of oxymorphone hydrochloride (Numorphan) analgesia employed for general surgery, including clinical experience with five hundred and twenty-eight patients. Cleveland Clinic Quarterly 28: 262-269, 1961

Bioequivalence of oxymorphone extended release and crush-resistant oxymorphone extended release. Drug Design, Development and Therapy 5: 455-463, 2012

The effects of ethanol on the bioavailability of oxymorphone extended-release tablets and oxymorphone crush-resistant extended-release tablets. Journal of Pain 13(1): 90-99, 2012

Oral oxymorphone #181. Journal of Palliative Medicine 13(1): 78-79, 2010