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Paraneoplastic limbic encephalitis presenting as acute viral encephalitis



Paraneoplastic limbic encephalitis presenting as acute viral encephalitis



Journal of Neuro-Oncology 75(2): 229-232



To describe a case of limbic encephalitis which initially presented as viral limbic encephalitis and during the clinical evaluation a renal carcinoma was diagnosed. Patient with history of peripheral paresis of right facial nerve, 1 month after symptoms appearance and treatment, developed fever, vomiting, grand mal seizure, decreased level of consciousness, confusion, hallucinations and agitation. The patient initially presented a clinical picture of viral LE. which confirmed by CSF. MRI brain showed areas with pathological intensity signal in the region of limbic system unilateral. During the clinical evaluation a renal carcinoma was discovered and a nephrectomy has been performed. Although PLE typically presents as a chronic or subacute disease, it may be fulminant and clinically indistinguishable from an acute HSVE. This association pose the problem of a possible relation between this two syndromes and the correct diagnosis is very important, because there are effective treatments.

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Accession: 049855232

Download citation: RISBibTeXText

PMID: 16283448

DOI: 10.1007/s11060-005-3671-9


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