+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Perioperative coronary artery spasm in off-pump coronary artery bypass grafting and its possible relation with perioperative hypomagnesemia



Perioperative coronary artery spasm in off-pump coronary artery bypass grafting and its possible relation with perioperative hypomagnesemia



Annals of Thoracic and Cardiovascular Surgery 12(1): 32-36



We experienced 3 cases of serious perioperative coronary artery spasm in off-pump coronary artery bypass grafting (OPCAB). In consideration of the causes, we directed our attention to hypomagnesemia, one of the triggers of coronary artery spasm. This study was performed to confirm the tendency to hypomagnesemia in OPCAB. First, we report 3 patients having severe coronary artery spasm immediately after OPCAB with consideration of the causes. Second, serial magnesium (Mg) value (xylidyl blue method, normal 1.9-3.1 mg/dl) was measured in 45 consecutive patients with OPCAB between April and October 2002, 1) before starting the operation, and 2) after the patient's entrance into the intensive care unit. Preoperative and postoperative values of Mg (mg/dl) were 2.1+/-0.3, 1.7+/-0.3, respectively (p < 0.01). Postoperative incidence of hypomagnesemia was as high as 89% of the patients (40 out of 45 patients). In this study and thereafter, we corrected hypomagnesemia with magnesium sulfate during and after OPCAB, and no perioperative coronary artery spasm occurred. Hypomagnesemia, one of the triggers of coronary artery spasm, is very common in OPCAB. We strongly recommend the correction of hypomagnesemia during and after OPCAB for the prevention of perioperative coronary artery spasm.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 049892816

Download citation: RISBibTeXText

PMID: 16572072


Related references

Comparison of perioperative myocardial injury between off-pump coronary artery bypass grafting and conventional coronary artery bypass grafting. Zhonghua Wai Ke Za Zhi 40(12): 930-931, 2003

Impact of off-pump coronary bypass grafting on the prevalence of adverse perioperative outcome in women undergoing coronary artery bypass grafting surgery. Annals of Thoracic Surgery 79(3): 807-12; Discussion 812-3, 2005

Importance of cerebral artery risk evaluation before off-pump coronary artery bypass grafting to avoid perioperative stroke. European Journal of Cardio-Thoracic Surgery 38(5): 568-572, 2011

Current Status of Off-pump Coronary Artery Bypass Grafting in Patients with Multiple Coronary Artery Disease Compared with On-pump Coronary Artery Bypass Grafting: The Korean National Cohort Study. Thoracic and Cardiovascular Surgeon 66(6): 470-476, 2018

Perioperative outcomes after on- and off-pump coronary artery bypass grafting. Texas Heart Institute Journal 41(2): 144-151, 2014

Perioperative advantages of off-pump coronary artery bypass grafting. Circulation Journal 66(9): 795-799, 2002

Perioperative multivessel coronary vasospasm as a cause of cardiogenic shock immediately after off-pump coronary artery bypass grafting surgery: a case report. Journal of Cardiology 45(2): 61-68, 2005

Perioperative optic neuropathy following off-pump coronary artery bypass grafting. Journal of Cardiovascular Surgery 47(5): 585-587, 2006

Off-pump coronary artery bypass grafting Perioperative results and 1-year follow-up. European Surgery 35(2): 107-110, 2003

Method of anesthesia and perioperative management for off-pump coronary artery bypass grafting. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 20(4): 207-209, 2008

Perioperative patency of coronary artery bypass grafting is not influenced by off-pump technique. Annals of Thoracic Surgery 80(6): 2132-2140, 2005

Perioperative outcomes in minimally invasive direct coronary artery bypass versus off-pump coronary artery bypass with sternotomy. Wideochirurgia i Inne Techniki Maloinwazyjne 12(3): 285-290, 2017

Coronary artery spasm induced by neuroleptic malignant syndrome during off-pump coronary artery bypass grafting; report of a case. Kyobu Geka. Japanese Journal of Thoracic Surgery 67(3): 247-250, 2015

Successful management of unremitting spasm of the nongrafted right coronary artery after off-pump coronary artery bypass grafting. Journal of Thoracic and Cardiovascular Surgery 133(6): 1649-1650, 2007

Perioperative myocardial infarction in patients undergoing off-pump coronary artery bypass grafting. Japanese Journal of Thoracic and Cardiovascular Surgery 51(8): 393-396, 2003