+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

A simple clinical method for predicting the benefit of prone vs. supine positioning in reducing heart exposure during left breast radiotherapy

A simple clinical method for predicting the benefit of prone vs. supine positioning in reducing heart exposure during left breast radiotherapy

RadioTherapy and Oncology 126(3): 487-492

Label="BACKGROUND AND PURPOSE">The benefit of reduced radiation heart exposure in the prone vs. supine position individually differs. In this prospective cohort study, the goal was to develop a simple method for the operation of a validated model for the prediction of preferable treatment position during left breast radiotherapy.Label="MATERIAL AND METHODS">In 100 cases, a single CT slice was utilized for the collection of the needed patient-specific data (in addition to body mass index, the distance of the LAD from the chest wall and the area of the heart included in the radiation fields at the middle of the heart in the supine position). Outcome was analyzed in relation to the full CT series acquired in both positions and dosimetric data.Label="RESULTS">Great consistency was found between the tested and original method regarding sensitivity and specificity. The prioritization of LAD dose, and the use of heart dose and position-specific dose constraints as safety measures ensure sensitivity and specificity values of 82.8% and 87.3%, respectively. In an additional "routine clinical practice" series of 60 patients the new method seemed feasible in routine clinical practice. External testing on a 28-case series indicated similar accuracy.Label="CONCLUSION">We consider this simple clinical tool appropriate for assisting individual positioning aiming at maximum heart protection during left breast irradiation.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 050094773

Download citation: RISBibTeXText

PMID: 29373194

DOI: 10.1016/j.radonc.2017.12.021

Related references

Prone vs supine positioning for breast cancer radiotherapy. JAMA 308(9): 861-863, 2012

Prone versus supine positioning for whole and partial-breast radiotherapy: A comparison of non-target tissue dosimetry. Breast Diseases: A Year Book Quarterly 22(1): 76-77, 2011

Prone versus supine positioning for whole and partial-breast radiotherapy: a comparison of non-target tissue dosimetry. RadioTherapy and Oncology 96(2): 178-184, 2010

Individual positioning: a comparative study of adjuvant breast radiotherapy in the prone versus supine position. International Journal of Radiation Oncology Biology Physics 75(1): 94, 2009

Improved cone-beam computed tomography in supine and prone breast radiotherapy. Surface reconstruction, radiation exposure, and clinical workflow. Strahlentherapie und Onkologie 189(11): 945-950, 2013

Prospective trial of individual optimal positioning (prone versus supine) for whole breast radiotherapy: results of 194 patients.. 2007

(P007) Cardiac and Left Anterior Descending Artery Sparing for Left Whole-Breast Radiation Therapy in the Prone vs Supine Free Breathing and Deep Inspiration Breath-Hold Positioning: A Single-Institution Experience. Oncology 30(Suppl.): -, 2016

Prone versus supine patient positioning during gated 99mTc-sestamibi SPECT: effect on left ventricular volumes, ejection fraction, and heart rate. Journal of Nuclear Medicine 45(12): 2016-2020, 2004

Patient positioning in prostate radiotherapy: Is prone better than supine?. International Journal of Radiation Oncology Biology Physics 47(2): 365-371, 2000

Feasibility study of individualized optimal positioning selection for left-sided whole breast radiotherapy: DIBH or prone. Journal of Applied Clinical Medical Physics 19(2): 218-229, 2018

Prospective study of postoperative whole breast radiotherapy for Japanese large-breasted women: a clinical and dosimetric comparisons between supine and prone positions and a dose measurement using a breast phantom. Bmc Cancer 16(1): 757, 2016

(P008) Prospective Assessment of Simulated Prone Whole-Breast Radiation Therapy vs Supine Whole-Breast Radiation Therapy With Respiratory Gating: Significant Lung Dose Reduction With Prone Positioning. Oncology 30(Suppl.): -, 2016

Feasibility of Intraoperative Breast MRI and the Role of Prone Versus Supine Positioning in Surgical Planning for Breast-Conserving Surgery. Breast Journal 23(6): 713-717, 2017

Intensity-modulated radiotherapy in patients with cervical cancer. An intra-individual comparison of prone and supine positioning. Radiation Oncology 5: 63, 2010

A randomized trial of supine vs. prone positioning in patients undergoing escalated dose conformal radiotherapy for prostate cancer. RadioTherapy and Oncology 70(1): 37-44, 2004