+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Rectosigmoid findings are not associated with proximal colon cancer: analysis of 6 196 consecutive cases undergoing total colonoscopy



Rectosigmoid findings are not associated with proximal colon cancer: analysis of 6 196 consecutive cases undergoing total colonoscopy



World Journal of Gastroenterology 11(15): 2249-2254



To review the risk of proximal colon cancer in patients undergoing colonoscopy. We estimated the risk of advanced proximal adenomas and cancers in 6 196 consecutive patients that underwent colonoscopy (mean age 60 years, 65% males, without prior history of colorectal examination). Neoplasms were classified as diminutive adenoma (5 mm or less), small adenoma (6-9 mm), advanced adenoma (10 mm or more, with villous component or high-grade dysplasia) and cancer (invasive adenocarcinoma). The sites of neoplasms were defined as rectosigmoid (rectum and sigmoid colon) and proximal colon (from cecum to descending colon). The trend of the prevalence of advanced proximal adenoma was to increase with severe rectosigmoid findings, while the prevalence of proximal colon cancer did not increase with severe rectosigmoid findings. Among the 157 patients with proximal colon cancer, 74% had no neoplasm in the rectosigmoid colon. Multivariate logistic-regression analysis revealed that age was the main predictor of proximal colon cancer and existence of rectosigmoid adenoma was not a predictor of proximal colon cancer. Sigmoidoscopy is inadequate for colorectal cancer screening, especially in older populations.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 050136408

Download citation: RISBibTeXText

PMID: 15818734


Related references

Rectosigmoid findings correlate with proximal colon adenoma but not with proximal colon cancer A study of 3285 consecutive cases examined by total colonoscopy. Gastroenterology 120(5 Supplement 1): A 603, April, 2001

Findings in the rectosigmoid in patients with advanced proximal colon neoplasia. Gastroenterology 118(4 Suppl 2 Part 1): A265, April, 2000

The incidence and clinical characteristics of proximal colonic polyps when the polyps are noted on rectosigmoid colon by colonoscopy. Korean Journal of Gastroenterology 62(1): 42-48, 2014

Prevalence of proximal colon serrated polyps in a population at average risk undergoing screening colonoscopy: a multicenter study. Clinics and Research in Hepatology and Gastroenterology 36(6): 604-608, 2013

Update: non-invasive screening test for colon cancer; colonoscopy refined. These new findings may improve accuracy and subsequent treatment for colon cancer; some experts disagree. Dukemedicine Healthnews 17(1): 4-4, 2011

Analysis of 21 cases treated by total laparoscopic rectosigmoid cancer surgery with transanal natural orifice specimen extraction. Zhonghua Yi Xue Za Zhi 93(26): 2082-2084, 2014

Higher prevalence of proximal colon polyps and villous histology in African-Americans undergoing colonoscopy at a single equal access center. Journal of Gastrointestinal Oncology 6(6): 638-643, 2015

Risk of advanced proximal adenoma and cancer according to rectosigmoid findings in the Korean population. Digestive Diseases and Sciences 51(12): 2206-2212, 2006

Cancer of the proximal colon after a "normal" colonoscopy. Bioscience Trends 3(4): 158-160, 2010

Rectosigmoid pathology as a markers of neoplasias in the proximal colon A cost benefit analysis of different diagnostic strategies. Anticancer Research 12(6A): 1841, 1992

Rectosigmoid polyps as a markers of neoplasms in the proximal colon A cost benefit analysis of different diagnostic strategies. Gastroenterology 104(4 SUPPL ): A385, 1993

Improving protection against proximal colon cancer by colonoscopy. Expert Review of Gastroenterology & Hepatology 5(6): 745-754, 2012

Protective association of colonoscopy against proximal and distal colon cancer and patterns in interval cancer. Gastrointestinal Endoscopy 82(3): 529-37.E1, 2016

Systematic review with meta-analysis: faecal occult blood tests show lower colorectal cancer detection rates in the proximal colon in colonoscopy-verified diagnostic studies. Alimentary Pharmacology & Therapeutics 43(7): 755-764, 2016

Two cases of lipoma of transverse colon which were confirmed by total colonoscopy. Journal of the Japan Society of Coloproctology 47(1): 80-85, 1994