+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Recurrent preeclampsia and perinatal outcome: a study of women with recurrent preeclampsia compared with women with preeclampsia who remained normotensive during their prior pregnancies



Recurrent preeclampsia and perinatal outcome: a study of women with recurrent preeclampsia compared with women with preeclampsia who remained normotensive during their prior pregnancies



Acta Obstetricia et Gynecologica Scandinavica 83(11): 1044-1048



To evaluate the impact of preeclampsia recurrence on perinatal outcome. A case-controlled study was performed in multiparous women who developed preeclampsia in index pregnancy (n = 64). Among these, women who had preeclampsia in previous pregnancies (n = 21) were compared to those who remained normotensive during their prior pregnancies (n = 43). Maternal and fetal variables were compared. Multivariate logistic analyses were performed to examine the impact of preeclampsia recurrence on fetal loss, preterm delivery, small for gestational age (SGA) occurrence and respiratory distress syndrome adjusted for confounding variables. No statistical significant difference was observed between the two groups in terms of age, delivery weeks, steroid use and laboratory markers. Fetal loss was higher in women with recurrent preeclampsia (19.0%) than in women with preeclampsia who had a normotensive pregnancy history (4.7%), with adjusted odds ratio (OR) of 5.77 [95% confidence interval (CI) 0.84-39.54]. Women with recurrent preeclampsia had a higher rate of perinatal loss compared to women with preeclampsia who were normotensive in their prior pregnancies.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 050138520

Download citation: RISBibTeXText

PMID: 15488119

DOI: 10.1080/j.0001-6349.2004.00424.x


Related references

Perinatal outcome in women with recurrent preeclampsia compared with women who develop preeclampsia as nulliparas. American Journal of Obstetrics & Gynecology 186(3): 422-426, 2002

Perinatal outcome in women with recurrent preeclampsia compared to those who develop preeclampsia as nullipara. American Journal of Obstetrics & Gynecology 184(1): S67, 2001

PP056. Cardiac adaptation in the preclinical phase of recurrent preeclampsia in women with a history of early preeclampsia. Pregnancy Hypertension 3(2): 87-88, 2013

Perinatal outcomes in women with preeclampsia and superimposed preeclampsia: do they differ?. American Journal of Obstetrics and Gynecology 204(6): 508.E1-7, 2011

Early-pregnancy Changes in Cardiac Diastolic Function in Women With Recurrent Preeclampsia and in Previously Preeclamptic Women Without Recurrent Disease. Obstetric Anesthesia Digest 32(3): 174-175, 2012

Pre-pregnant prediction of recurrent preeclampsia in normotensive thrombophilic formerly preeclamptic women receiving prophylactic antithrombotic medication. Journal of the Society for Gynecologic Investigation 12(2): 112-117, 2005

The Ala-9Val (Mn-SOD) and Arg213Gly (EC-SOD) polymorphisms in the pathogenesis of preeclampsia in Romanian women: association with the severity and outcome of preeclampsia. Journal of Maternal-Fetal and Neonatal Medicine 25(7): 895-900, 2012

Comparing maternal and perinatal outcomes in pregnancies complicated by preeclampsia superimposed chronic hypertension and preeclampsia alone. Clinical and Experimental Obstetrics and Gynecology 43(2): 212-215, 2016

Elevated levels of protein AMBP in cerebrospinal fluid of women with preeclampsia compared to normotensive pregnant women. Proteomics.ClinicalApplications11(1-2):, 2017

Serum leptin measured in early pregnancy is higher in women with preeclampsia compared with normotensive pregnant women. Hypertension 65(3): 594-599, 2015

The severity of preeclampsia and the timing of delivery influences the severity and recurrency rate of preeclampsia among primiparous women with preeclampsia. American Journal of Obstetrics & Gynecology 184(1): S78, 2001

Uterine Doppler velocimetry predicts normotensive preeclampsia in pregnancies with fetal growth retardation Evidences from placental pathology and perinatal outcome. American Journal of Obstetrics & Gynecology 172(1 Part 2): 374, 1995

Ionized calcium levels in umbilical cord blood of women with preeclampsia and normotensive pregnancies. Journal of Maternal-Fetal and Neonatal Medicine 25(2): 203-205, 2012

Persistent Maternal Cardiac Dysfunction After Preeclampsia Identifies Patients at Risk for Recurrent Preeclampsia. Hypertension 67(4): 748-753, 2016

The effect of the D1-C785T polymorphism in the type 1 iodothyronine deiodinase gene on the circulating thyroid hormone levels in Romanian women with preeclampsia. Association with the degree of severity and pregnancy outcome of preeclampsia. Gynecological Endocrinology 28(5): 386-390, 2012