EurekaMag
+ Most Popular
Cunninghamia lanceolata plantations in China
Mammalian lairs in paleo ecological studies and palynology
Studies on technological possibilities in utilization of anhydrous milk fat for production of recombined butter-like products
Should right-sided fibroelastomas be operated upon?
Large esophageal lipoma
Apoptosis in the mammalian thymus during normal histogenesis and under various in vitro and in vivo experimental conditions
Poissons characoides nouveaux ou non signales de l'Ilha do Bananal, Bresil
Desensitizing efficacy of Colgate Sensitive Maximum Strength and Fresh Mint Sensodyne dentifrices
Administration of fluid by subcutaneous infusion: revival of a forgotten method
Tundra mosquito control - an impossible dream?
Schizophrenia for primary care providers: how to contribute to the care of a vulnerable patient population
Geochemical pattern analysis; method of describing the Southeastern limestone regional aquifer system
Incidence of low birth weights in a hospital of Mexico City
Tabanidae
Graded management intensity of grassland systems for enhancing floristic diversity
Microbiology and biochemistry of cheese and fermented milk
The ember tetra: a new pygmy characid tetra from the Rio das Mortes, Brazil, Hyphessobrycon amandae sp. n. (Pisces, Characoidei)
Risk factors of contrast-induced nephropathy in patients after coronary artery intervention
Renovation of onsite domestic wastewater in a poorly drained soil
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Systolic blood pressure in a population of infants in the first year of life: the Brompton study
Haematological studies in rats fed with metanil yellow
Studies on pasteurellosis. I. A new species of Pasteurella encountered in chronic fowl cholera
Dormancy breaking and germination of Acacia salicina Lindl. seeds
therapy of lupus nephritis. a two-year prospective study

Role of diffusion-weighted MR imaging in cervical lymphadenopathy


Role of diffusion-weighted MR imaging in cervical lymphadenopathy



European Radiology 16(7): 1468-1477



ISSN/ISBN: 0938-7994

PMID: 16557366

DOI: 10.1007/s00330-005-0133-x

The role of diffusion-weighted magnetic resonance imaging (MRI) for differentiation between various causes of cervical lymphadenopathy was evaluated. In a prospective study, 31 untreated patients (22 males and nine females, aged 5-70 years) with 87 cervical lymph nodes underwent diffusion-weighted MRI before performance of neck dissection (n=14), surgical biopsy (n=9) or core biopsy (n=8). Diffusion-weighted MR images were acquired with a b factor of 0 and 1,000 s/mm2 using single-shot echo-planar sequence. Apparent diffusion coefficient (ADC) maps were reconstructed for all patients. The signal intensity of the lymph nodes was assessed on images obtained at b=0 or 1,000 s/mm2 and from the ADC maps. The ADC value of lymph nodes was also calculated. On the ADC map, malignant nodes showed either low (n=52) or mixed (n=20) signal intensity and benign nodes revealed high (n=13) or low (n=2) signal intensity. The mean ADC value of metastatic (1.09+/-0.11x10(-3) mm2/s) and lymphomatous (0.97+/-0.27x10(-3) mm2/s) lymph nodes was significantly lower than that of benign (1.64+/-0.16x10(-3) mm2/s) cervical lymph nodes (P<0.04). When an ADC value of 1.38x10(-3) mm2/s was used as a threshold value for differentiating malignant from benign lymph nodes, the best results were obtained with an accuracy of 96%, sensitivity of 98%, specificity of 88%, positive predictive value of 98.5% and negative predictive value of 83.7%. The smallest detected lymph node was 0.9 cm. In conclusion, diffusion-weighted MRI with ADC mapping is a new promising technique that can differentiate malignant from benign lymph nodes and delineate the solid viable part of the lymph node for biopsy. This technique provides additional useful physiological and functional information regarding characterization of cervical lymph nodes.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 050232988

Download citation: RISBibTeXText

Related references

Role of diffusion-weighted MR imaging in cervical lymphadenopathy. Clinical Imaging 31(1): 75-0, 2007

Value of diffusion-weighted MR imaging performed with quantitative apparent diffusion coefficient values for cervical lymphadenopathy. Journal of Magnetic Resonance Imaging: Jmri 38(3): 663-670, 2013

Malignant cervical lymphadenopathy: diagnostic accuracy of diffusion-weighted MR imaging. Radiology 245(3): 806-813, 2007

Assessment of parametrial invasion of cervical carcinoma, the role of T2-weighted MRi and diffusion weighted imaging with or without fusion. Clinical Radiology 74(10): 790-796, 2019

Diffusion-weighted magnetic resonance imaging in cervical lymphadenopathy: report of three cases of patients with Bartonella henselae infection mimicking malignant disease. Acta Radiologica 50(8): 914-916, 2009

Diffusion-weighted imaging in patients with acute brain ischemia at 3 T: current possibilities and future perspectives comparing conventional echoplanar diffusion-weighted imaging and fast spin echo diffusion-weighted imaging sequences using BLADE (PROPELLER). Investigative Radiology 44(6): 351-359, 2009

Diffusion-weighted imaging volume and diffusion-weighted imaging volume growth in acute stroke: associations with fluid-attenuated inversion recovery hyperintensities-diffusion-weighted imaging mismatch and functional outcome. Neuroreport 30(13): 875-881, 2019

Diffusion tensor imaging focusing on lower cervical spinal cord using 2D reduced FOV interleaved multislice single-shot diffusion-weighted echo-planar imaging: comparison with conventional single-shot diffusion-weighted echo-planar imaging. Magnetic Resonance Imaging 33(4): 401-406, 2015

Detection of prostate cancer with magnetic resonance imaging: optimization of T1-weighted, T2-weighted, dynamic-enhanced T1-weighted, diffusion-weighted imaging apparent diffusion coefficient mapping sequences and MR spectroscopy, correlated with biopsy and histopathological findings. Journal of Computer Assisted Tomography 36(1): 30-45, 2012

Parametrial invasion in cervical cancer: fused T2-weighted imaging and high-b-value diffusion-weighted imaging with background body signal suppression at 3 T. Radiology 274(3): 734-741, 2015

Diffusion-weighted MR imaging of mediastinal lymphadenopathy. Japanese Journal of Radiology 34(5): 385, 2016

Characterization of mediastinal lymphadenopathy with diffusion-weighted imaging. Magnetic Resonance Imaging 29(2): 167-172, 2011

Diffusion-weighted MR imaging of mediastinal lymphadenopathy in children. Japanese Journal of Radiology 33(8): 449-454, 2015

Diffusion-weighted MR imaging for whole body metastatic disease and lymphadenopathy. Magnetic Resonance Imaging Clinics of North America 17(2): 245-261, 2009

Apparent Diffusion Coefficient of Diffusion-Weighted Imaging in Evaluation of Cervical Intervertebral Disc Degeneration: An Observational Study with 3.0 T Magnetic Resonance Imaging. Biomed Research International 2018: 6843053, 2018