EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Study of intestinal malabsorption diseases as cause of monosymptomatic short stature



Study of intestinal malabsorption diseases as cause of monosymptomatic short stature



Jornal de Pediatria 74(3): 213-216



OBJECTIVE: This study was carried out in order to evaluate the etiology of monosymptomatic childhood short stature (below the third percentile or with growth rate of less than 5 cm/year) with emphasis on causes due to intestinal malabsorption. METHODS: Each patient was submitted to endocrinological, biochemical and hematological investigation. Determination of serum anti-gliadin antibodies, fecal fat, chloride levels in sweat, jejunal biopsy and bone age was also obtained.RESULTS: A total of 51 children was studied, most of them belonging to the group of normal variants. Four children had abnormally high sweat chloride, compatible with the diagnosis of cystic fibrosis. These children were asymptomatic regarding respiratory and gastrointestinal tract. CONCLUSIONS: We conclude that cystic fibrosis, besides celiac disease, must be included in the differential diagnosis of short stature in childhood.

(PDF emailed within 1 workday: $29.90)

Accession: 050427805

Download citation: RISBibTeXText

PMID: 14685622



Related references

Short stature as the primary manifestation of monosymptomatic celiac disease. Journal of Pediatric Gastroenterology and Nutrition 14(1): 12-16, 1992

The diagnostic value of the gliadin antibody test in the search of monosymptomatic celiac disease in children with short stature. Cocuk Sagligi ve Hastaliklari Dergisi 39(2): 245-251, 1996

A case-comparison study of the characteristics of children with a short stature syndrome induced by stress (Hyperphagic Short Stature) and a consecutive series of unaffected stressed children. Journal of Child Psychology and Psychiatry and Allied Disciplines 40(6): 969-978, 1999

Short stature and Helicobacter pylori infection in italian children: prospective multicentre hospital based case-control study. The Italian Study Group on Short Stature and H pylori. Bmj 317(7157): 514-515, 1998

Short-duration fatty meal loading for the assessment of intestinal malabsorption syndromes in children: preliminary study. Pediatrie 47(2): 141-144, 1992

Short stature and risk for cardiovascular diseases morbidity and mortality The Framingham Heart Study. Circulation 86(4 SUPPL 1): I327, 1992

Lysozyme concentrations in the intestinal mucosa in malabsorption syndromes and chronic inflammatory intestinal diseases. Klinische Padiatrie 196(1): 36-39, 1984

Clinical analysis and genetic diagnosis of short-limb inherited short stature diseases in children. Zhongguo Dang Dai Er Ke Za Zhi 15(11): 932-936, 2014

Deletion of the region containing the short stature homeobox-containing gene in a derived Xp223 translocation patient with short stature by FISH. American Journal of Human Genetics 61(4 SUPPL ): A138, 1997

Short stature and turner skeletal features in an 11-year-old boy with a ring y chromosome missing the short stature homeobox containing gene. Clinical Pediatric Endocrinology 14(2): 45-47, 2005

Short stature homeobox-containing gene deletion screening by fluorescence in situ hybridisation in patients with short stature. European Journal of Pediatrics 160(9): 561-565, September, 2001

Heterozygous mutations in natriuretic peptide receptor-B (NPR2) gene as a cause of short stature in patients initially classified as idiopathic short stature. Journal of Clinical Endocrinology and Metabolism 98(10): E1636-E1644, 2013

Breast hypoplasia and disproportionate short stature in the ear, patella, short stature syndrome: expansion of the phenotype?. Journal of Medical Genetics 37(9): 719-721, 2001

Breast hypoplasia and disproportionate short stature in the ear, patella, short stature syndrome: Expansion of the phenotype?. Journal of Medical Genetics 37(9): 719-721, 2000