+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

The Metabolic Formation of Gamma-(3-Pyridyl)-Gamma-Hydroxybutyric Acid and its Possible Intermediary Role in the Mammalian Metabolism of Nicotine



The Metabolic Formation of Gamma-(3-Pyridyl)-Gamma-Hydroxybutyric Acid and its Possible Intermediary Role in the Mammalian Metabolism of Nicotine



Journal of Biological Chemistry 239: 3981-3989




Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 050545481

Download citation: RISBibTeXText

PMID: 14260867


Related references

The metabolic formation of gamma- -gamma-hydroxybutyric acid and its possible intermediary role in the mammalian metabolism of nicotine. J Biol Chem 239(11): 3981-3989, 1964

Studies on the degradation of the pyrrolidine ring of (--)-nicotine in vivo. Formation of gamma-(3-pyridyl)-gamma-oxobutyric acid. Journal of Biological Chemistry 238: 1807-1812, 1963

Feasibility of D-glucuronate to enhance gamma-hydroxybutyric acid metabolism during gamma-hydroxybutyric acid toxicity: pharmacokinetic and pharmacodynamic studies. Biopharmaceutics and Drug Disposition 28(1): 1-11, 2007

Application of a convenient extraction procedure to analyze gamma-hydroxybutyric acid in fatalities involving gamma-hydroxybutyric acid, gamma-butyrolactone, and 1,4-butanediol. Journal of Analytical Toxicology 25(7): 576-582, 2001

Studies on nicotine metabolism: The formation of gamma- -gamma-methylaminobutyric acid. FED PROC 19(1 Pt 1): 30, 1960

Formation and regional distribution of gamma-hydroxybutyric acid in mammalian brain. Biochemical Pharmacology 19(12): 3013-3019, 1970

The role of monocarboxylate transporter 2 and 4 in the transport of gamma-hydroxybutyric acid in mammalian cells. Drug Metabolism and Disposition: the Biological Fate of Chemicals 35(8): 1393-1399, 2007

Characterization of the discriminative stimulus effects of gamma-hydroxybutyric acid as a means for unraveling the neurochemical basis of gamma-hydroxybutyric acid actions and its similarities to those of ethanol. Alcohol 20(3): 237-245, 2000

Gamma-Hydroxybutyric acid induced spike and wave discharges in rats: relation to high-affinity [3H]gamma-hydroxybutyric acid binding sites in the thalamus and cortex. Neuroscience 56(1): 11-21, 1993

Preliminary Report On The Metabolism Of Gamma-Butyrolactone And Gamma-Hydroxybutyric Acid. Biochemical Pharmacology 14: 177-178, 1965

Novel radioiodinated {gamma}-hydroxybutyric acid analogues for radiolabeling and Photolinking of high-affinity {gamma}-hydroxybutyric acid binding sites. Journal of Pharmacology and Experimental Therapeutics 335(2): 458-464, 2010

Selective gamma-hydroxybutyric acid receptor ligands increase extracellular glutamate in the hippocampus, but fail to activate G protein and to produce the sedative/hypnotic effect of gamma-hydroxybutyric acid. Journal of Neurochemistry 87(3): 722-732, 2003

A process of formation of gamma-aminobutyric acid and gamma-amino-beta-hydroxybutyric acid in the brain. Sogo Igaku. Medicine 19: 386-387, 1962

Effect of intravenous administration of gamma-hydroxybutyric and succinic acids on the metabolism of gamma-aminobutyric acid in the brain. Voprosy Meditsinskoi Khimii 19(4): 401-403, 1973

Chronic gamma-hydroxybutyric-acid use followed by gamma-hydroxybutyric-acid withdrawal mimic schizophrenia: a case report. Cases Journal 2: 7520, 2009