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The changing field of vaccine development in the genomics era



The changing field of vaccine development in the genomics era



Pharmacogenomics 5(6): 597-600



An improved understanding of the human immune system and the genetic make-up of pathogens, together with advances in instrumentation and bioinformatics, have provided new insights into the variation of immune responses to vaccines within the human population. Pathogen variation and the diversity of the immune system components within the human population make the design of universal vaccines difficult. New subunit vaccines that target immunologically similar subgroups of the human population and representative pathogen variants are emerging from research that combines immunomics, pathogen genomics, and high-throughput instrumentation.

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Accession: 050583945

Download citation: RISBibTeXText

PMID: 15335280

DOI: 10.1517/14622416.5.6.597


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