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The relationship between lymphangiogenesis and cervical lymph node micrometastasis in oral squamous cell carcinoma



The relationship between lymphangiogenesis and cervical lymph node micrometastasis in oral squamous cell carcinoma



Zhonghua Kou Qiang Yi Xue Za Zhi 39(3): 221-223



To probe the relationship between lymphangiogenesis and cervical lymph node micrometastasis in oral squamous cell carcinoma. The microlymphatic vessel density was detected with enzyme histo-chemical method in 47 cases of oral squamous cell carcinoma and 10 cases of normal oral mucosa; 355 lymphnodes were detected with immunohistochemically using monoantibody AE3. The mean MLVD was 14.04 +/- 6.92 in tumor group, or 5.48 +/- 2.62 in normal group. The difference was (P < 0.001). The percentage of tumor with expression CK was 48.9%. The mean MLVD was 16.94 +/- 5.43 in CK positive group, or 11.26 +/- 5.00 in CK negative group, There was difference significant (P < 0.001). Lymphangiogenesis plays a key role in cervical lymph node micrometastasis of oral squamous cell carcinoma.

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Accession: 050712720

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PMID: 15196391


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