Section 51
Chapter 50,852

Treatment with infliximab in a patient with ankylosing spondylitis and Crohn's disease

Rednic, S.; Marinescu, C.; Chira, R.; Rogojan, L.; Rednic, N.

Journal of Gastrointestinal and Liver Diseases Jgld 15(4): 379-382


ISSN/ISBN: 1842-1121
PMID: 17205151
Accession: 050851299

The association of Crohn's disease and ankylosing spondylitis is described in up to 30% of cases. Treatment of both conditions is not an easy task. We present the case of a 53 year old woman, diagnosed with colonic Crohn's disease and ankylosing spondilitis, treated initially with increasing doses of sulphasalazine and moderate dose of corticosteroids, with the persistence of severe gastrointestinal and articular symptoms. She underwent therapy with tumor necrosis factor alpha (TNFalpha) inhibitor infliximab, with a spectacular improvement of symptoms, signs and quality of life.

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