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Type 2 diabetes presenting as diabetic ketoacidosis in adolescence



Type 2 diabetes presenting as diabetic ketoacidosis in adolescence



Diabetic Medicine 20(5): 416-417



We report two black adolescent subjects who presented with diabetic ketoacidosis, but who lacked autoimmune markers and demonstrated clinical and biochemical characteristics more typical of Type 2 diabetes, including obesity, acanthosis nigricans, positive family history for Type 2 diabetes, and Type 2 diabetic dyslipidaemia. Subsequent to acute presentation, insulin was discontinued in both subjects and excellent glycaemic control was achieved with metformin therapy alone. Four months following acute presentation, both had adequate C-peptide responses to intravenous glucagon. Type 2 diabetes can present as diabetic ketoacidosis in obese adolescent subjects.

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Accession: 050874484

Download citation: RISBibTeXText

PMID: 12752492

DOI: 10.1046/j.1464-5491.2003.00942.x


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