+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Unruptured intracranial aneurysms: natural history and clinical management. Update on the international study of unruptured intracranial aneurysms



Unruptured intracranial aneurysms: natural history and clinical management. Update on the international study of unruptured intracranial aneurysms



Neuroimaging Clinics of North America 16(3): 383



In guiding treatment decisions for all patients with unruptured intracranial aneurysms, it is important to compare size-, site-, and group-specific natural history data with size-, site- and age-specific treatment morbidity and mortality data. Because patient age has a major effect on operative morbidity and mortality, but relatively little effect on natural history, surgical treatment of an UIA patient over age 50 and any treatment of UIA patients over age 70 should be considered with particular vigilance. Optimally, patients should be evaluated and treated at high-volume centers in a setting that emphasizes neurovascular teamwork and unbiased presentation and delivery of different therapeutic option, including the option of observation, which is often appropriate for patients with UIAs.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 050890435

Download citation: RISBibTeXText

PMID: 16935706

DOI: 10.1016/j.nic.2006.04.005


Related references

The natural history of unruptured intracranial aneurysms Prospective data from the international study of unruptured intracranial aneurysms. Neurology 58(7 Suppl. 3): A97, 2002

Unruptured Intracranial Aneurysms. A Critical Review of the International Study of Unruptured Intracranial Aneurysms (ISUIA) and of Appropriate Methods to Address the Clinical Problem. Interventional Neuroradiology 14(1): 85-96, 2008

Unruptured intracranial aneurysms in the Familial Intracranial Aneurysm and International Study of Unruptured Intracranial Aneurysms cohorts: differences in multiplicity and location. Journal of Neurosurgery 117(1): 60-64, 2012

Unruptured intracranial aneurysms--risk of rupture and risks of surgical intervention. International Study of Unruptured Intracranial Aneurysms Investigators. New England Journal of Medicine 339(24): 1725-1733, 1998

Simulation of the natural history of cerebral aneurysms based on data from the International Study of Unruptured Intracranial Aneurysms. Journal of Neurosurgery 104(2): 188-194, 2006

Factors related to location of unruptured cerebral aneurysms Report of the International Study of Unruptured Intracranial Aneurysms investigators. Stroke 30(1): 270, 1999

Unruptured intracranial aneurysms: natural history and management decisions. Neurosurgical Focus 17(5): E6, 2004

Prevalence, natural history and management of unruptured intracranial aneurysms. Nihon Rinsho. Japanese Journal of Clinical Medicine 51 Suppl: 322-328, 1993

Unruptured intracranial aneurysms: natural history and management decisions. Neurosurgical Focus 17(5): 1-6, 2004

Natural history and general management of unruptured intracranial aneurysms. Neurosurgical Focus 17(5): E1, 2004

Natural history and general management of unruptured intracranial aneurysms. Neurosurgical Focus 17(5): 1-6, 2004

Interobserver variability in angiographic measurement and morphologic characterization of intracranial aneurysms: a report from the International Study of Unruptured Intracranial Aneurysms. Ajnr. American Journal of Neuroradiology 17(8): 1407-1415, 1996

Unruptured intracranial aneurysms: some questions answered, many questions remain. Re: Pelz D. CURES and the dilemma of unruptured intracranial aneurysms. Can J Neuro Sci. 2011 Mar;38(2):191-2. Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques 38(5): 785-787, 2011

Unruptured intracranial aneurysms in patients over 80 years: natural history and management implications. Acta Neurochirurgica 160(9): 1773-1777, 2018

Unruptured intracranial aneurysms: epidemiology, natural history, management options, and familial screening. Lancet. Neurology 13(4): 393-404, 2014