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A 7-year follow-up of patients with thyroid cysts and pseudocysts treated with percutaneous ethanol injection: volume change and cost analysis



A 7-year follow-up of patients with thyroid cysts and pseudocysts treated with percutaneous ethanol injection: volume change and cost analysis



Journal of Ultrasound 12(3): 107-111



SommarioLe cisti e le pseudo cisti tiroidee o cisti emorragiche sono una patologia abbastanza frequente tra quelle tiroidee. La terapia d'elezione è sempre stata quella chirurgica, ma prende sempre più piede l'alcolizzazione per via percutanea (PEI). La PEI è una terapia derivata da quella dei noduli epatici. Utilizzata inizialmente per i noduli solidi iperfunzionanti, è oggi utilizzata esclusivamente sulle cisti. Scopo di questo studio è stato quello di valutare l'efficacia della PEI sulla riduzione volumetrica delle cisti tiroidee dopo 12 e 84 mesi e di confrontare il rapporto costo-beneficio con la chirurgia. Sono stati considerati in serie successiva 110 pazienti, tutti trattati mediante alcolizzazione previo studio citologico che escludeva una patologia neoplastica. Tutti i soggetti avevano rifiutato l'intervento chirurgico. Uno dei pazienti è deceduto durante il follow-up per ictus cerebri. Ogni paziente è stato sottoposto in media a 5.3 ± 2.7 sedute. Dopo 12 mesi la riduzione volumetrica è stata del 82.6%; dopo 84 mesi del 93.03%. Gli effetti collaterali come la disfonia con risoluzione spontanea si sono verificati in 2 soli casi. Inoltre, comparando i costi della PEI con l'intervento chirurgico si evince un risparmio (per quanto riguarda i nostri soggetti) di circa 200.000 euro. Quindi la PEI si pone come prima scelta nei confronti della chirurgia sia per l'efficacia, sia per il risparmio economico da parte del SSN.

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Accession: 051057965

Download citation: RISBibTeXText

PMID: 23396632

DOI: 10.1016/j.jus.2009.06.002


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