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A mutation suppressing a sumoylation site in the MITF transcriptional regulator predisposes to melanoma and renal carcinoma


A mutation suppressing a sumoylation site in the MITF transcriptional regulator predisposes to melanoma and renal carcinoma



Bulletin du Cancer 99(2): 119-120



ISSN/ISBN: 0007-4551

PMID: 22423361


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(PDF emailed within 1 workday: $29.90)

Accession: 051170658

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Related references

A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma. Nature 480(7375): 94-98, 2011

A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma. Nature 480(7375): 99-103, 2011

MITF: une clé génétique du mélanome et du carcinome rénal ? - MITF: a genetic key to melanoma and renal cell carcinoma?. Ms. Medecine Sciences 28(3): 258-261, 2012

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A conditional zebrafish MITF mutation reveals MITF levels are critical for melanoma promotion vs. regression in vivo. Journal of Investigative Dermatology 134(1): 133-140, 2014

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Sumoylation modulates transcriptional activity of MITF in a promoter-specific manner. Pigment Cell Research 18(4): 265-277, 2005

MITF: a genetic key to melanoma and renal cell carcinoma?. Medecine Sciences: M/S 28(3): 258-261, 2012

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Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF. Proceedings of the National Academy of Sciences of the United States of America 108(43): E924-E933, 2011