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A synthetic receptor for nicotine from a dynamic combinatorial library



A synthetic receptor for nicotine from a dynamic combinatorial library



Organic Letters 14(21): 5404-5407



Designing synthetic receptors that bind biologically relevant guests in an aqueous solution remains a considerable challenge. We now report a new synthetic receptor for nicotine, selected from a dynamic combinatorial library, that binds this guest in water at neutral pH through a combination of hydrophobic and π-π interactions.

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Accession: 051270523

Download citation: RISBibTeXText

PMID: 23067115

DOI: 10.1021/ol302260n


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