+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Acne vulgaris in children and adolescents

Acne vulgaris in children and adolescents

Minerva Pediatrica 63(4): 293-304

Acne vulgaris is a very common inflammatory skin disease originating from the pilosebaceous unit. Peak incidence is at puberty, but acne can affect all age groups. Prepubertal acne is rare, but important to recognize as diagnostic and therapeutic procedures differ from pubertal acne. Acne neonatorum is a mild, self-limiting disease, whereas acne infantum commonly presents with moderate to severe lesions and high risk of scarring thus requiring early intervention. Mid-childhood or prepubertal acne raises the suspicion of hyperandrogenemia, further investigations are indicated to rule out underlying disease. The same applies to any patient with very severe acne, acne not responding to therapy or unusual clinical presentation. Etiopathogenesis of acne is not yet fully understood. Familiy history is the most important risk factor to develop severe acne and scarring. The relevance of life style factors such as smoking or diet is controversial. Lately high carbohydrate diet and dairy products have been implicated as aggravating factors. Mild acne normally responds to topical monotherapy, in moderate disease combination of two synergistically acting substances (e.g. benzoyl peroxid plus antibiotic, benzoyl peroxid plus retinoid, retinoid plus antibiotic, benzoyl peroxid plus azelaic acid) will improve clinical response. Retinoids and/or benzoylperoxid have been shown to be effective in maintenance therapy. In patients with severe disease or high risk of scarring systemic therapy with antibiotics, oral contraceptives with antiandrogenic properties and in particularly isotretinoin as most effective acne treatment should be considered early to avoid physical and emotional scars.

Please choose payment method:

(PDF emailed within 1 workday: $29.90)

Accession: 051334791

Download citation: RISBibTeXText

PMID: 21909065

Related references

The pathophysiology of acne vulgaris in children and adolescents, Part 1. Cutis 74(2): 92-97, 2004

The pathophysiology of acne vulgaris in children and adolescents, part 2: Tailoring treatment. Cutis 74(3): 189-192, 2004

Medication Adherence in Children and Adolescents with Acne Vulgaris in Medicaid: A Retrospective Study Analysis. Pediatric Dermatology 33(1): 49-55, 2016

Dairy Intake and Acne Vulgaris: A Systematic Review and Meta-Analysis of 78,529 Children, Adolescents, and Young Adults. Nutrients 10(8), 2018

Randomized, controlled trial split-faced study of 595-nm pulsed dye laser in the treatment of acne vulgaris and acne erythema in adolescents and early adulthood. International Journal of Dermatology 56(8): 884-888, 2017

Guidelines for the management of acne vulgaris in adolescents. Paediatric Drugs 5(5): 301-313, 2003

Quality-of-life of adolescents with acne vulgaris. Acta Medica Croatica 64(4): 247-251, 2011

On the Question of the Relation Between Sex Hormones and Acne Vulgaris. a Contribution on the Etiology of Acne Vulgaris. Die Medizinische Welt 22: 1223-1226, 1964

Dissatisfaction and acne vulgaris in male adolescents and associated factors. Anais Brasileiros de Dermatologia 89(4): 576-579, 2014

Anxiety, depression, and nature of acne vulgaris in adolescents. International Journal of Dermatology 39(5): 354-357, 2000

Self-esteem and mental health in adolescents with acne vulgaris. European Neuropsychopharmacology 28: S46-S47, 2018

New and emerging drugs for the treatment of acne vulgaris in adolescents. Expert Opinion on PharmacoTherapy 2019: 1-16, 2019

Relationship between acne vulgaris in 187 adolescents and Pityrosporum infection. 2008

Characteristics of Acne Vulgaris In European Adolescents And Patients Perceptions. Value in Health 18(7): A425, 2015

Efficacy and safety of dapsone gel 5% for the treatment of acne vulgaris in adolescents. Cutis 81(2): 171-178, 2008