Acute hemorrhagic pancreatitis due to the use of valproic acid in a child
Ozaydin, E.; Yükselgüngör, H.; Köse, G.ül.şe.
European Journal of Paediatric Neurology Ejpn Official Journal of the European Paediatric Neurology Society 12(2): 141-143
2008
ISSN/ISBN: 1090-3798
PMID: 17881258
DOI: 10.1016/j.ejpn.2007.07.006
Accession: 051357383
Acute pancreatitis is rarely seen in children, and it is often drug induced. Valproic acid (VPA) is one of the most widely used anticonvulsants for children all over the world. We present 11-year-old boy developing pancreatitis after 6 months of therapy with VPA. The symptoms of pancreatitis subsided within 2 weeks after discontinuation of VPA. It seems that the prognosis of VPA-associated acute pancreatitis depends on early diagnosis, timely withdrawal of the offending agent and the treatment.