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Alpha asymmetry in infants at risk for autism spectrum disorders



Alpha asymmetry in infants at risk for autism spectrum disorders



Journal of Autism and Developmental Disorders 45(2): 473-480



An emerging focus of research on autism spectrum disorder (ASD) targets the identification of early-developing ASD endophenotypes using infant siblings of affected children. One potential neural endophenotype is resting frontal electroencephalogram (EEG) alpha asymmetry, a metric of hemispheric organization. Here, we examined the development of frontal EEG alpha asymmetry in ASD high-risk and low-risk infant populations. Our findings demonstrate that low and high-risk infants show different patterns of alpha asymmetry at 6 months of age and opposite growth trajectories in asymmetry over the following 12 months. These results support the candidacy of alpha asymmetry as an early neural ASD endophenotype.

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Accession: 051439756

Download citation: RISBibTeXText

PMID: 23989937

DOI: 10.1007/s10803-013-1926-4


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