+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Anatomic versus physiologic assessment of coronary artery disease. Role of coronary flow reserve, fractional flow reserve, and positron emission tomography imaging in revascularization decision-making



Anatomic versus physiologic assessment of coronary artery disease. Role of coronary flow reserve, fractional flow reserve, and positron emission tomography imaging in revascularization decision-making



Journal of the American College of Cardiology 62(18): 1639-1653



Angiographic severity of coronary artery stenosis has historically been the primary guide to revascularization or medical management of coronary artery disease. However, physiologic severity defined by coronary pressure and/or flow has resurged into clinical prominence as a potential, fundamental change from anatomically to physiologically guided management. This review addresses clinical coronary physiology-pressure and flow-as clinical tools for treating patients. We clarify the basic concepts that hold true for whatever technology measures coronary physiology directly and reliably, here focusing on positron emission tomography and its interplay with intracoronary measurements.

(PDF emailed within 0-6 h: $19.90)

Accession: 051538520

Download citation: RISBibTeXText

PMID: 23954338

DOI: 10.1016/j.jacc.2013.07.076


Related references

Fractional flow reserve, absolute and relative coronary blood flow velocity reserve in relation to the results of technetium-99m sestamibi single-photon emission computed tomography in patients with two-vessel coronary artery disease. Journal of the American College of Cardiology 37(5): 1316-1322, 2001

Quantitative magnetic resonance perfusion imaging detects anatomic and physiologic coronary artery disease as measured by coronary angiography and fractional flow reserve. Journal of the American College of Cardiology 50(6): 514-522, 2007

Fractional flow reserve-guided coronary artery bypass grafting: can intraoperative physiologic imaging guide decision making?. Journal of Thoracic and Cardiovascular Surgery 146(4): 824-835.E1, 2013

Rationale and design of the Fractional Flow Reserve versus Angiography for Multivessel Evaluation (FAME) 3 Trial: a comparison of fractional flow reserve-guided percutaneous coronary intervention and coronary artery bypass graft surgery in patients with multivessel coronary artery disease. American Heart Journal 170(4): 619-626.E2, 2015

Coronary flow velocity reserve in three major coronary arteries by transthoracic echocardiography for the functional assessment of coronary artery disease: a comparison with fractional flow reserve. European Heart Journal Cardiovascular Imaging 15(4): 399-408, 2015

Clinical Outcomes and Cost-Effectiveness of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention in Patients With Stable Coronary Artery Disease: Three-Year Follow-Up of the FAME 2 Trial (Fractional Flow Reserve Versus Angiography for Multivessel Evaluation). Circulation 137(5): 480-487, 2017

Comparison of adenosine magnetic resonance perfusion imaging with invasive coronary flow reserve and fractional flow reserve in patients with suspected coronary artery disease. International Journal of Cardiology 147(1): 184-186, 2011

Long-term effect of beta-blockers on myocardial blood flow and coronary flow reserve in coronary artery disease-patients assessed with positron emission tomography. European Heart Journal 22(Abstract Supplement): 573, 2001

Accuracy and usefulness of noninvasive fractional flow reserve from computed tomographic coronary angiography: comparison with myocardial perfusion imaging, echocardiographic coronary flow reserve, and invasive fractional flow reserve. Cardiovascular Intervention and Therapeutics 32(1): 66-71, 2015

Operational utility of fractional flow reserve (FFR) in guiding the decision for coronary revascularization in patients of coronary artery disease in Indian scenario. Indian Heart Journal 66: S113-S114, 2014

Diastolic fractional flow reserve to assess the functional severity of moderate coronary artery stenoses: comparison with fractional flow reserve and coronary flow velocity reserve. Circulation 102(19): 2365-2370, 2000

Impact of Revascularization on Absolute Myocardial Blood Flow as Assessed by Serial [ 15 O]H 2 O Positron Emission Tomography Imaging: A Comparison With Fractional Flow Reserve. Circulation. Cardiovascular Imaging 11(5): E007417, 2018

Fractional flow reserve versus angiography for guiding percutaneous coronary intervention in patients with multivessel coronary artery disease: 2-year follow-up of the FAME (Fractional Flow Reserve Versus Angiography for Multivessel Evaluation) study. Journal of the American College of Cardiology 56(3): 177-184, 2010

Noninvasive Measurement of Coronary Flow Reserve in Patients with Coronary Artery Disease with 015 Water and Positron Emission Tomography (PET). Clinical Science 76(S20): 23p.2-23p, 1989

Meta-Analysis of Diagnostic Performance of Coronary Computed Tomography Angiography, Computed Tomography Perfusion, and Computed Tomography-Fractional Flow Reserve in Functional Myocardial Ischemia Assessment Versus Invasive Fractional Flow Reserve. American Journal of Cardiology 116(9): 1469-1478, 2016