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Anti-yo associated paraneoplastic cerebellar degeneration in a man with large cell cancer of the lung



Anti-yo associated paraneoplastic cerebellar degeneration in a man with large cell cancer of the lung



Case Reports in Neurological Medicine 2013: 725936



Purkinje cell cytoplasmic antibody type 1 (PCA-1), or anti-Yo, is the most frequently detected autoantibody in paraneoplastic cerebellar degeneration (PCD). The vast majority of cases of anti-Yo PCD, however, occur in females over 60 years old and are associated with gynecologic tumors. Only 10 cases have been reported in males, and only 2 were associated with cancer of the lung. Here we describe the youngest known case of PCA-1 positive PCD in a male, whose lung tumor was undetectable even on FDG-PET.

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Accession: 051571659

Download citation: RISBibTeXText

PMID: 24167748

DOI: 10.1155/2013/725936


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