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Aporphine alkaloids, clerodane diterpenes, and other constituents from Tinospora cordifolia

Aporphine alkaloids, clerodane diterpenes, and other constituents from Tinospora cordifolia

Fitoterapia 81(6): 485-489

Phytochemical investigation of the methanol extract of Tinospora cordifolia aerial parts led to the isolation of four new and seven known compounds. The structures of two new aporphine alkaloids, N-formylasimilobine 2-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranoside (tinoscorside A, 1) and N-acetylasimilobine 2-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranoside (tinoscorside B, 2), a new clerodane diterpene, tinoscorside C (3), and a new phenylpropanoid, sinapyl 4-O-beta-D-apiofuranosyl-(1-->6)-O-beta-D-glucopyranoside (tinoscorside D, 6) were determined by extensive spectroscopic methods including FTICR-MS and 1D and 2D NMR.

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Accession: 051603389

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PMID: 20080155

DOI: 10.1016/j.fitote.2010.01.005

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