+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Association between local traffic-generated air pollution and preeclampsia and preterm delivery in the south coast air basin of California



Association between local traffic-generated air pollution and preeclampsia and preterm delivery in the south coast air basin of California



Environmental Health Perspectives 117(11): 1773-1779



Preeclampsia is a major complication of pregnancy that can lead to substantial maternal and perinatal morbidity, mortality, and preterm birth. Increasing evidence suggests that air pollution adversely affects pregnancy outcomes. Yet few studies have examined how local traffic-generated emissions affect preeclampsia in addition to preterm birth. We examined effects of residential exposure to local traffic-generated air pollution on preeclampsia and preterm delivery (PTD). We identified 81,186 singleton birth records from four hospitals (1997-2006) in Los Angeles and Orange Counties, California (USA). We used a line-source dispersion model (CALINE4) to estimate individual exposure to local traffic-generated nitrogen oxides (NO(x)) and particulate matter < 2.5 mum in aerodynamic diameter (PM(2.5)) across the entire pregnancy. We used logistic regression to estimate effects of air pollution exposures on preeclampsia, PTD (gestational age < 37 weeks), moderate PTD (MPTD; gestational age < 35 weeks), and very PTD (VPTD; gestational age < 30 weeks). We observed elevated risks for preeclampsia and preterm birth from maternal exposure to local traffic-generated NO(x) and PM(2.5). The risk of preeclampsia increased 33% [odds ratio (OR) = 1.33; 95% confidence interval (CI), 1.18-1.49] and 42% (OR = 1.42; 95% CI, 1.26-1.59) for the highest NO(x) and PM(2.5) exposure quartiles, respectively. The risk of VPTD increased 128% (OR = 2.28; 95% CI, 2.15-2.42) and 81% (OR = 1.81; 95% CI, 1.71-1.92) for women in the highest NO(x) and PM(2.5) exposure quartiles, respectively. Exposure to local traffic-generated air pollution during pregnancy increases the risk of preeclampsia and preterm birth in Southern California women. These results provide further evidence that air pollution is associated with adverse reproductive outcomes.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 051675237

Download citation: RISBibTeXText

PMID: 20049131

DOI: 10.1289/ehp.0800334


Related references

Association between Local Traffic-Generated Air Pollution and Preeclampsia and Preterm Delivery in the South Coast Air Basin of California. Environmental Health Perspectives 117(11): 1773-1779, 2009

Inhalation intake of ambient air pollution in California's South Coast Air Basin. Atmospheric Environment 40(23): 4381-4392, 2006

Penetration and duration of oxidant air pollution in the South Coast Air Basin of California. Journal of the Air Pollution Control Association 22(11): 882-886, 1972

Some aspects of atmospheric pollution and urbanization in the santa barbara segment of the south coast air basin california. Southwestern And Rocky Mountain Division American Association Fo The Advancement Of Science, And Arizona Academy Of Scienceacts. Rocky Mountain Division American Association For The Advancement Of Science And The Fifteenth Annual Meeting Arizona Academy Of Sceince. April 21-24,: . 30, 1971

The relative impacts of distributed and centralized generation of electricity on local air quality in the South Coast Air Basin of California. Energy Policy 39(9): 4999-5007, 2011

Traffic-related air pollution and risk of preterm birth in the San Joaquin Valley of California. Annals of Epidemiology 24(12): 888-95e4, 2014

Development of Late-Onset Preeclampsia in Association with Road Densities as a Proxy for Traffic-Related Air Pollution. Fetal Diagnosis and Therapy 39(1): 21-27, 2016

Artifact sulfate and nitrate formation at 2 sites in the south coast air basin a collaborative study between the south coast air quality management district and the california usa air resources board. Environmental Science & Technology 15(1): 79-83, 1981

Preeclampsia mediates the association between shorter height and increased risk of preterm delivery. International Journal of Epidemiology 46(5): 1690-1698, 2017

Association of Lipid Profile in Pregnancy with Preeclampsia, Gestational Diabetes Mellitus, and Preterm Delivery. Cureus 9(7): E1420, 2017

The association of ambient air pollution and traffic exposures with selected congenital anomalies in the San Joaquin Valley of California. American Journal of Epidemiology 177(10): 1074-1085, 2013

Tracking Air Pollution in the South Coast Basin. Pages 433-437 1973, 1973

Association between source-specific particulate matter air pollution and hs-CRP: local traffic and industrial emissions. Environmental Health Perspectives 122(7): 703-710, 2014

A study of the atmospheric lead pollution in Seville, Spain. Influence of meteorology and traffic, and relationship with other traffic-generated pollutants. International Journal of Environmental Analytical Chemistry 24(4): 283-295, 1986

Association between PM 2.5 and PM 2.5 Constituents and Preterm Delivery in California, 2000-2006. Paediatric and Perinatal Epidemiology 31(5): 424-434, 2017