+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Bats, viruses and humans: coronaviruses on the rise?



Bats, viruses and humans: coronaviruses on the rise?



Berliner und Munchener Tierarztliche Wochenschrift 126(11-12): 509-513



The outbreak of the SARS coronavirus in 2002/2003 and the recent disease cases with a new human coronavirus (originally designated EMC-CoV, recently renamed MERS-CoV) have put the focus onto the virus family Coronaviridae. Both viruses appeared to have managed to jump over the species barrier from a bat reservoir to the human population. Bats are considered to serve as a natural reservoir for coronaviruses infecting mammals. An important factor for crossing the species-barrier is the adaptation to a new receptor on cells of the new host species. During evolution coronaviruses have developed a large diversity of binding specificities demonstrating the high flexibility of the coronaviral spike protein, which is responsible for binding to target cells.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 051761990

Download citation: RISBibTeXText

PMID: 24511826


Related references

Molecular survey of RNA viruses in Hungarian bats: discovering novel astroviruses, coronaviruses, and caliciviruses. Vector Borne and Zoonotic Diseases 14(12): 846-855, 2014

Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats. Viruses 7(12): 6279-6290, 2015

Viruses in bats and potential spillover to animals and humans. Current Opinion in Virology 34: 79-89, 2019

Bats and zoonotic viruses: can we confidently link bats with emerging deadly viruses?. Memorias do Instituto Oswaldo Cruz 110(1): 1-22, 2015

Intraspecies diversity of SARS-like coronaviruses in Rhinolophus sinicus and its implications for the origin of SARS coronaviruses in humans. Journal of General Virology 91(Pt 4): 1058-1062, 2010

Bats and their virome: an important source of emerging viruses capable of infecting humans. Current Opinion in Virology 3(1): 84-91, 2013

Immunological Control of Viral Infections in Bats and the Emergence of Viruses Highly Pathogenic to Humans. Frontiers in Immunology 8: 1098, 2017

Differential sensitivity of bat cells to infection by enveloped RNA viruses: coronaviruses, paramyxoviruses, filoviruses, and influenza viruses. Plos one 8(8): E72942, 2013

Bats and Coronaviruses. Viruses 11(1):, 2019

Coronaviruses in bats from Mexico. Journal of General Virology 94(Pt 5): 1028-1038, 2013

Molecular diversity of coronaviruses in bats. Virology 351(1): 180-187, 2006

Coronaviruses in South African bats. Vector Borne and Zoonotic Diseases 13(7): 516-519, 2013

Extensive diversity of coronaviruses in bats from China. Virology 507: 1-10, 2017

Highly diversified coronaviruses in neotropical bats. Journal of General Virology 94(Pt 9): 1984-1994, 2013

Detection of coronaviruses in bats of various species in Italy. Viruses 5(11): 2679-2689, 2013