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Brainstem encephalitis following influenza vaccination: favorable response to steroid treatment

Brainstem encephalitis following influenza vaccination: favorable response to steroid treatment

Vaccine 27(52): 7253-7256

We report a 44-year-old man presenting with left hemiparesis following influenza vaccination. The neuroimaging studies showed a large, contrast-enhancing brainstem lesion and multiple punctate lesions suggesting microhaemorrhages in both cerebral hemispheres. The patient showed a remarkable response to high dose steroid treatment. Detailed diagnostic studies failed to yield any results supporting inflammatory/demyelinating diseases, suggesting that influenza vaccination might have been associated with the clinical findings. Our case implies that vaccination might be related with a wide range of clinical syndromes, including brainstem encephalitis.

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Accession: 051859057

Download citation: RISBibTeXText

PMID: 19748576

DOI: 10.1016/j.vaccine.2009.08.111

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