+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Calcium-dependent protein kinases in plants: evolution, expression and function

Calcium-dependent protein kinases in plants: evolution, expression and function

Plant and Cell Physiology 55(3): 551-569

Calcium-dependent protein kinases (CPKs) are plant proteins that directly bind calcium ions before phosphorylating substrates involved in metabolism, osmosis, hormone response and stress signaling pathways. CPKs are a large multigene family of proteins that are present in all plants studied to date, as well as in protists, oomycetes and green algae, but are not found in animals and fungi. Despite the increasing evidence of the importance of CPKs in developmental and stress responses from various plants, a comprehensive genome-wide analysis of CPKs from algae to higher plants has not been undertaken. This paper describes the evolution of CPKs from green algae to plants using a broadly sampled phylogenetic analysis and demonstrates the functional diversification of CPKs based on expression and functional studies in different plant species. Our findings reveal that CPK sequence diversification into four major groups occurred in parallel with the terrestrial transition of plants. Despite significant expansion of the CPK gene family during evolution from green algae to higher plants, there is a high level of sequence conservation among CPKs in all plant species. This sequence conservation results in very little correlation between CPK evolutionary groupings and functional diversity, making the search for CPK functional orthologs a challenge.

(PDF emailed within 0-6 h: $19.90)

Accession: 051907982

Download citation: RISBibTeXText

PMID: 24363288

DOI: 10.1093/pcp/pct200

Related references

Function of plant calcium-dependent protein kinases in the activation of abiotic and pathogen-related stress responses and potential application in the generation of stress-resistant plants. Floriculture, ornamental and plant biotechnology: 367-372, 2006

Calcium-dependent protein kinases and neuronal function. Trends in Pharmacological Sciences 5: 188-192, 1984

Characterization of two calcium-dependent protein kinases implicated in stimulus-response coupling in plants. Current Topics in Plant Biochemistry and Physiology 9: 129-140, 1990

Role of calcium/calmodulin-dependent protein kinases in expression of Fos protein in the nucleus tractus solitarii after sustained hypertension. Neuroscience 95(1): 155-162, 2000

Phosphorylation of the sodium, potassium-ATPase by calcium, phospholipid-dependent and cAMP-dependent protein kinases: Mapping of the region phosphorylated by calcium, phospholipid-dependent protein kinase. Journal of Bioenergetics & Biomembranes 25(1): 61-66, 1993

Endogenous substrate proteins for calcium calmodulin dependent calcium phospho lipid dependent and cyclic amp dependent protein kinases in mouse pancreatic islets. Biochemical Journal 221(1): 247-254, 1984

Biochemical regulation of in vivo function of plant calcium-dependent protein kinases (CDPK). Biochimica et Biophysica Acta 1833(7): 1582-1589, 2013

Cloning and expression of a rat cDNA with homology to calcium/calmodulin-dependent protein kinases. Pediatric Research 35(4 PART 2): 65A, 1994

cDNA cloning and prokaryotic expression of maize calcium-dependent protein kinases. Biochimica et Biophysica Acta 1350(2): 109-114, 1997

Differential centrifugation analysis of subcellular distribution of substrates of cyclic amp dependent calcium calmodulin dependent and calcium phospholipid dependent protein kinases in rat sertoli cells. Biology of Reproduction 36(SUPPL 1): 143, 1987

Differential expression of genes for cyclin-dependent protein kinases in rice plants. Plant Physiology 119(1): 31-40, 1999

Focal adhesion kinases and calcium/calmodulin-dependent protein kinases regulate protein tyrosine phosphorylation in stallion sperm. Biology of Reproduction 88(6): 138, 2013

Mitogen-activated protein kinases and calcium-dependent protein kinases are involved in wounding-induced ethylene biosynthesis in Arabidopsis thaliana. Plant, Cell and Environment 41(1): 134-147, 2017

Genome-wide expression patterns of calcium-dependent protein kinases in Toxoplasma gondii. Parasites and Vectors 8: 304, 2017

Cross talk among calcium, hydrogen peroxide, and nitric oxide and activation of gene expression involving calmodulins and calcium-dependent protein kinases in Ulva compressa exposed to copper excess. Plant Physiology 158(3): 1451-1462, 2012