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Cardiac arrest after intracisternal papaverine instillation during intracranial aneurysm surgery. Case report



Cardiac arrest after intracisternal papaverine instillation during intracranial aneurysm surgery. Case report



Journal of Neurosurgery 113(4): 760-762



Cerebral vasospasm induced by aneurysmal subarachnoid hemorrhage is still a leading cause of morbidity and death. This 50-year-old man underwent surgery for aneurysm clipping. After the aneurysm was clipped, papaverine was instilled into the surgical area. Bradycardia, hypotension, and sinus arrest developed in the first minute after applying the papaverine. Thus, the authors concluded that the application of papaverine to the surgical area can result in fatal bradycardia and hypotension.

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Accession: 051939385

Download citation: RISBibTeXText

PMID: 19961315

DOI: 10.3171/2009.11.JNS09899


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